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Jul 14, 2016 (publication date) through Nov 25, 2024
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Publication Name
World Journal of Gastroenterology
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1007-9327
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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA
| For: | Vecchione G, Grasselli E, Voci A, Baldini F, Grattagliano I, Wang DQ, Portincasa P, Vergani L. Silybin counteracts lipid excess and oxidative stress in cultured steatotic hepatic cells. World J Gastroenterol 2016; 22(26): 6016-6026 [PMID: 27468193 DOI: 10.3748/wjg.v22.i26.6016] |
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| URL: | https://www.wjgnet.com/1007-9327/full/v22/i26/6016.htm |
| Number | Citing Articles |
| 1 |
Lin Tian, Weimin Li, Tan Wang. Therapeutic effects of silibinin on LPS-induced acute lung injury by inhibiting NLRP3 and NF-κB signaling pathways. Microbial Pathogenesis 2017; 108: 104 doi: 10.1016/j.micpath.2017.05.011
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| 2 |
Elena Grasselli, Francesca Baldini, Giulia Vecchione, Paulo Oliveira, Vilma Sard�o, Adriana Voci, Piero Portincasa, Laura Vergani. Excess fructose and fatty acids trigger a model of non‑alcoholic fatty liver disease progression in vitro: Protective effect of the flavonoid silybin. International Journal of Molecular Medicine 2019; doi: 10.3892/ijmm.2019.4234
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| 3 |
Shuang CUI, Xiao-Jie PAN, Chao-Liang GE, Yi-Tong GUO, Peng-Fei ZHANG, Ting-Ting YAN, Ji-Yu ZHOU, Qing-Xian HE, Long-Hao CHENG, Guang-Ji WANG, Hai-Ping HAO, Hong WANG. Silybin alleviates hepatic lipid accumulation in methionine-choline deficient diet-induced nonalcoholic fatty liver disease in mice via peroxisome proliferator-activated receptor α. Chinese Journal of Natural Medicines 2021; 19(6): 401 doi: 10.1016/S1875-5364(21)60039-0
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| 4 |
Anushna Sen, Sayeepriyadarshini Anakk. Jekyll and Hyde: nuclear receptors ignite and extinguish hepatic oxidative milieu. Trends in Endocrinology & Metabolism 2021; 32(10): 790 doi: 10.1016/j.tem.2021.07.009
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| 5 |
Agostino Di Ciaula, Giuseppe Calamita, Harshitha Shanmugam, Mohamad Khalil, Leonilde Bonfrate, David Q.-H. Wang, Gyorgy Baffy, Piero Portincasa. Mitochondria Matter: Systemic Aspects of Nonalcoholic Fatty Liver Disease (NAFLD) and Diagnostic Assessment of Liver Function by Stable Isotope Dynamic Breath Tests. International Journal of Molecular Sciences 2021; 22(14): 7702 doi: 10.3390/ijms22147702
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| 6 |
Dexin Li, Jingxin Zhang, Yuxin Jin, Yaoxuan Zhu, Xiaoqing Lu, Xinmei Huo, Chunshui Pan, Lijun Zhong, Kai Sun, Li Yan, Lulu Yan, Ping Huang, Quan Li, Jing-Yan Han, Yin Li. Silibinin inhibits PM2.5-induced liver triglyceride accumulation through enhancing the function of mitochondrial Complexes I and II. Frontiers in Pharmacology 2024; 15 doi: 10.3389/fphar.2024.1435230
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| 7 |
Mohamad Khalil, Hala Khalifeh, Francesca Baldini, Annalisa Salis, Gianluca Damonte, Ahmad Daher, Adriana Voci, Laura Vergani. Antisteatotic and antioxidant activities of Thymbra spicata L. extracts in hepatic and endothelial cells as in vitro models of non-alcoholic fatty liver disease. Journal of Ethnopharmacology 2019; 239: 111919 doi: 10.1016/j.jep.2019.111919
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| 8 |
Jia-Yi Cai, Jian Li, Yong-Na Hou, Kai Ma, Guo-Dong Yao, Wei-Wei Liu, Toshihiko Hayashi, Kikuji Itoh, Shin-ichi Tashiro, Satoshi Onodera, Takashi Ikejima. Concentration-dependent dual effects of silibinin on kanamycin-induced cells death in Staphylococcus aureus. Biomedicine & Pharmacotherapy 2018; 102: 782 doi: 10.1016/j.biopha.2018.03.133
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| 9 |
Yujie Bai, Jing Zhang, Jialin Li, Minghui Liao, Yajing Zhang, Yufeng Xia, Zhifeng Wei, Yue Dai. Silibinin, a commonly used therapeutic agent for non‐alcohol fatty liver disease, functions through upregulating intestinal expression of fibroblast growth factor 15/19. British Journal of Pharmacology 2024; 181(19): 3663 doi: 10.1111/bph.16431
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| 10 |
Ignazio Grattagliano, Agostino Di Ciaula, Jacek Baj, Emilio Molina-Molina, Harshitha Shanmugam, Gabriella Garruti, David Q. -H. Wang, Piero Portincasa. Mitochondrial Regulation. Methods in Molecular Biology 2021; 2310: 201 doi: 10.1007/978-1-0716-1433-4_12
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| 11 |
Agostino Di Ciaula, David Q.-H. Wang, Emilio Molina-Molina, Raquel Lunardi Baccetto, Giuseppe Calamita, Vincenzo O. Palmieri, Piero Portincasa. Bile Acids and Cancer: Direct and Environmental-Dependent Effects. Annals of Hepatology 2017; 16: S87 doi: 10.5604/01.3001.0010.5501
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| 12 |
Qiang Ou, Yuanyuan Weng, Siwei Wang, Yajuan Zhao, Feng Zhang, Jianhua Zhou, Xiaolin Wu. Silybin Alleviates Hepatic Steatosis and Fibrosis in NASH Mice by Inhibiting Oxidative Stress and Involvement with the Nf-κB Pathway. Digestive Diseases and Sciences 2018; 63(12): 3398 doi: 10.1007/s10620-018-5268-0
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| 13 |
Youwei Zheng, Shiting Wang, Jialiang Wu, Yong Wang. Mitochondrial metabolic dysfunction and non-alcoholic fatty liver disease: new insights from pathogenic mechanisms to clinically targeted therapy. Journal of Translational Medicine 2023; 21(1) doi: 10.1186/s12967-023-04367-1
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| 14 |
Devaraj Ezhilarasan, Kulanthaivel Langeswaran. Hepatocellular Interactions of Potential Nutraceuticals in the Management of Inflammatory NAFLD. Cell Biochemistry and Function 2024; 42(7) doi: 10.1002/cbf.4112
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| 15 |
Gabriela Svobodová, Martin Horní, Eva Velecká, Iva Boušová. Metabolic dysfunction-associated steatotic liver disease-induced changes in the antioxidant system: a review. Archives of Toxicology 2024; doi: 10.1007/s00204-024-03889-x
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| 16 |
Mariangela Centrone, Patrizia Gena, Marianna Ranieri, Annarita Di Mise, Mariagrazia D’Agostino, Maria Mastrodonato, Maria Venneri, Davide De Angelis, Stefano Pavan, Antonella Pasqualone, Carmine Summo, Valentina Fanelli, Giovanna Valenti, Giuseppe Calamita, Grazia Tamma. In Vitro and In Vivo Nutraceutical Characterization of Two Chickpea Accessions: Differential Effects on Hepatic Lipid Over-Accumulation. Antioxidants 2020; 9(3): 268 doi: 10.3390/antiox9030268
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| 17 |
Xiao-juan Rao, Yu-min Wu, Yan Wang, Shuang-wei Shi. WITHDRAWN: JIP3 deficiency protects mice from high fat diet-induced liver injury. Biochemical and Biophysical Research Communications 2017; doi: 10.1016/j.bbrc.2017.09.109
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| 18 |
Sheng Zhong, Yuxiang Fan, Qi Yan, Xingyu Fan, Bo Wu, Yujuan Han, Ying Zhang, Yong Chen, Huimao Zhang, Junqi Niu. The therapeutic effect of silymarin in the treatment of nonalcoholic fatty disease. Medicine 2017; 96(49): e9061 doi: 10.1097/MD.0000000000009061
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| 19 |
Saumya Srivastava, Anjana Pandey. Anticancer Plants: Clinical Trials and Nanotechnology. 2017; : 181 doi: 10.1007/978-981-10-8216-0_6
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| 20 |
Caio Mateus Silva, Gustavo Duarte Ferrari, Luciane Carla Alberici, Osmar Malaspina, Karen C. M. Moraes. Cellular and molecular effects of silymarin on the transdifferentiation processes of LX-2 cells and its connection with lipid metabolism. Molecular and Cellular Biochemistry 2020; 468(1-2): 129 doi: 10.1007/s11010-020-03717-7
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| 21 |
Agostino Di Ciaula, Salvatore Passarella, Harshitha Shanmugam, Marica Noviello, Leonilde Bonfrate, David Q.-H. Wang, Piero Portincasa. Nonalcoholic Fatty Liver Disease (NAFLD). Mitochondria as Players and Targets of Therapies?. International Journal of Molecular Sciences 2021; 22(10): 5375 doi: 10.3390/ijms22105375
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| 22 |
Andrea Amaroli, Silvia Ravera, Francesca Baldini, Stefano Benedicenti, Isabella Panfoli, Laura Vergani. Photobiomodulation with 808-nm diode laser light promotes wound healing of human endothelial cells through increased reactive oxygen species production stimulating mitochondrial oxidative phosphorylation. Lasers in Medical Science 2019; 34(3): 495 doi: 10.1007/s10103-018-2623-5
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| 23 |
Chuanwei Yao, Wenxing Huang, Yongtao Liu, Zhaoyang Yin, Ning Xu, Yuliang He, Xiongfei Wu, Kangsen Mai, Qinghui Ai.
Effects of dietary silymarin (SM) supplementation on growth performance, digestive enzyme activities, antioxidant capacity and lipid metabolism gene expression in large yellow croaker (
Larimichthys crocea
) larvae
. Aquaculture Nutrition 2020; 26(6): 2225 doi: 10.1111/anu.13159
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| 24 |
Daniel Figueiredo Vanzan, Ester Puna Goma, Fernanda Resende Locatelli, Thiago da Silva Honorio, Priscila de Souza Furtado, Carlos Rangel Rodrigues, Valeria Pereira de Sousa, Hilton Antônio Mata dos Santos, Flávia Almada do Carmo, Alice Simon, Alexandre dos Santos Pyrrho, António José Ribeiro, Lucio Mendes Cabral. Evaluation of Silybin Nanoparticles against Liver Damage in Murine Schistosomiasis mansoni Infection. Pharmaceutics 2024; 16(5): 618 doi: 10.3390/pharmaceutics16050618
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| 25 |
Farah Diab, Hawraa Zbeeb, Lama Zeaiter, Francesca Baldini, Aldo Pagano, Velia Minicozzi, Laura Vergani. Unraveling the metabolic activities of bioactive compounds on cellular models of hepatosteatosis and adipogenesis through docking analysis with PPARs. Scientific Reports 2024; 14(1) doi: 10.1038/s41598-024-78374-7
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| 26 |
Emilio Molina-Molina, Harshitha Shanmugam, Domenica Di Palo, Ignazio Grattagliano, Piero Portincasa. Mitochondrial Regulation. Methods in Molecular Biology 2021; 2310: 179 doi: 10.1007/978-1-0716-1433-4_11
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| 27 |
Chunqiu Fang, Jingzhou Zhang, Jiajun Han, Yuting Lei, Zhanhong Cao, Jianheng Pan, Zhi Pan, Zhong Zhang, Ning Qu, Haoming Luo, Yan Ma, Dong Han. Tiaogan Jiejiu Tongluo Formula attenuated alcohol-induced chronic liver injury by regulating lipid metabolism in rats. Journal of Ethnopharmacology 2023; 317: 116838 doi: 10.1016/j.jep.2023.116838
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| 28 |
Meng-yi Chi, Hong Zhang, Ya-xian Wang, Xi-peng Sun, Quan-jun Yang, Cheng Guo, Kunihiro Sakuma. Silibinin Alleviates Muscle Atrophy Caused by Oxidative Stress Induced by Cisplatin through ERK/FoxO and JNK/FoxO Pathways. Oxidative Medicine and Cellular Longevity 2022; 2022: 1 doi: 10.1155/2022/5694223
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| 29 |
Kyung-Hoon Sun, Min-Young Lee, Young-Jin Jeon. Inhibition of Phagocytosis by Silibinin in Mouse Macrophages. Current Issues in Molecular Biology 2023; 45(10): 8126 doi: 10.3390/cimb45100513
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| 30 |
Ignazio Grattagliano, Ornella de Bari, Domenica Di Palo, Fabrizio Montecucco, Federico Carbone, Paulo J. Oliveira, David Q.-H. Wang, Piero Portincasa. Mitochondrial Biology and Experimental Therapeutics. 2018; : 91 doi: 10.1007/978-3-319-73344-9_7
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| 31 |
Xinyu Wu, Jiawei Chen, Kaixin Ping, Yan Xia, Mengxin Li, Yannan Xiang, Huimao Feng, Jingquan Dong. Silybin mitigated liver and brain damage after difenoconazole exposure: Crosstalk between oxidative stress, inflammation, ferroptosis and apoptosis. Pesticide Biochemistry and Physiology 2024; 202: 105942 doi: 10.1016/j.pestbp.2024.105942
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| 32 |
Xiao-jun Ma, Hai-zhou Xing, Gao-fei Ren, Xiao-juan Rao, Zhi-zhen Li. JIP3 knockout protects mice against high fat diet-induced liver injury. Biochemical and Biophysical Research Communications 2018; 497(3): 819 doi: 10.1016/j.bbrc.2018.01.178
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| 33 |
Carlotta Giorgi, Saverio Marchi, Ines C.M. Simoes, Ziyu Ren, Giampaolo Morciano, Mariasole Perrone, Paulina Patalas-Krawczyk, Sabine Borchard, Paulina Jędrak, Karolina Pierzynowska, Jędrzej Szymański, David Q. Wang, Piero Portincasa, Grzegorz Węgrzyn, Hans Zischka, Pawel Dobrzyn, Massimo Bonora, Jerzy Duszynski, Alessandro Rimessi, Agnieszka Karkucinska-Wieckowska, Agnieszka Dobrzyn, Gyorgy Szabadkai, Barbara Zavan, Paulo J. Oliveira, Vilma A. Sardao, Paolo Pinton, Mariusz R. Wieckowski. Mitochondria and Longevity. International Review of Cell and Molecular Biology 2018; 340: 209 doi: 10.1016/bs.ircmb.2018.05.006
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| 34 |
Runbin Sun, Dan Xu, Qingli Wei, Bangling Zhang, Jiye Aa, Guangji Wang, Yuan Xie. Silybin ameliorates hepatic lipid accumulation and modulates global metabolism in an NAFLD mouse model. Biomedicine & Pharmacotherapy 2020; 123: 109721 doi: 10.1016/j.biopha.2019.109721
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| 35 |
Karla MacDonald-Ramos, Adriana Monroy, Mariana Bobadilla-Bravo, Marco Cerbón. Silymarin Reduced Insulin Resistance in Non-Diabetic Women with Obesity. International Journal of Molecular Sciences 2024; 25(4): 2050 doi: 10.3390/ijms25042050
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| 36 |
Alejandra Butanda-Nuñez, Octavio Rodríguez-Cortés, Espiridión Ramos-Martínez, Marco Antonio Cerbón, Galileo Escobedo, Anahí Chavarría. Silybin restores glucose uptake after tumour necrosis factor-alpha and lipopolysaccharide stimulation in 3T3-L1 adipocytes. Adipocyte 2024; 13(1) doi: 10.1080/21623945.2024.2374062
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Ignazio Grattagliano, Liliana P. Montezinho, Paulo J. Oliveira, Gema Frühbeck, Javier Gómez-Ambrosi, Fabrizio Montecucco, Federico Carbone, Mariusz R. Wieckowski, David Q.-H. Wang, Piero Portincasa. Targeting mitochondria to oppose the progression of nonalcoholic fatty liver disease. Biochemical Pharmacology 2019; 160: 34 doi: 10.1016/j.bcp.2018.11.020
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Salvatore Nesci, Anna Spagnoletta, Francesca Oppedisano. Inflammation, Mitochondria and Natural Compounds Together in the Circle of Trust. International Journal of Molecular Sciences 2023; 24(7): 6106 doi: 10.3390/ijms24076106
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| 39 |
Han Zhang, Guangdong Qi, Kexin Wang, Jiawen Yang, Yuntian Shen, Xiaoming Yang, Xin Chen, Xinlei Yao, Xiaosong Gu, Lei Qi, Chun Zhou, Hualin Sun. Oxidative stress: Roles in skeletal muscle atrophy. Biochemical Pharmacology 2023; 214: 115664 doi: 10.1016/j.bcp.2023.115664
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| 40 |
Hawraa Zbeeb, Hala Khalifeh, Giulio Lupidi, Francesca Baldini, Lama Zeaiter, Mohamad Khalil, Annalisa Salis, Gianluca Damonte, Laura Vergani. Polyphenol-enriched extracts of Sarcopoterium spinosum fruits for counteracting lipid accumulation and oxidative stress in an in vitro model of hepatic steatosis. Fitoterapia 2024; 172: 105743 doi: 10.1016/j.fitote.2023.105743
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| 41 |
Ziyue Zhang, Bozhi Shi, Xueze Lv, Yingchao Dong, Lei Li, Zhaofei Xia. Effects of silybin supplementation on growth performance, serum indexes and liver transcriptome of Peking ducks. Frontiers in Veterinary Science 2024; 10 doi: 10.3389/fvets.2023.1325115
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| 42 |
Chun-Xue Cui, Jing-Na Deng, Li Yan, Yu-Ying Liu, Jing-Yu Fan, Hong-Na Mu, Hao-Yu Sun, Ying-Hong Wang, Jing-Yan Han. Silibinin Capsules improves high fat diet-induced nonalcoholic fatty liver disease in hamsters through modifying hepatic de novo lipogenesis and fatty acid oxidation. Journal of Ethnopharmacology 2017; 208: 24 doi: 10.1016/j.jep.2017.06.030
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| 43 |
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