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For: Minchenko OH, Tsuchihara K, Minchenko DO, Bikfalvi A, Esumi H. Mechanisms of regulation of PFKFB expression in pancreatic and gastric cancer cells. World J Gastroenterol 2014; 20(38): 13705-13717 [PMID: 25320508 DOI: 10.3748/wjg.v20.i38.13705]
URL: https://www.wjgnet.com/1007-9327/full/v20/i38/13705.htm
Number Citing Articles
1
Chao Lu, Pengyun Qiao, Yonghong Sun, Chune Ren, Zhenhai Yu. Positive regulation of PFKFB3 by PIM2 promotes glycolysis and paclitaxel resistance in breast cancerClinical and Translational Medicine 2021; 11(4) doi: 10.1002/ctm2.400
2
Longzhou Zhang, Zengjin Liu, Yang Dong, Lingchang Kong. E2F2 drives glioma progression via PI3K/AKT in a PFKFB4-dependent mannerLife Sciences 2021; 276: 119412 doi: 10.1016/j.lfs.2021.119412
3
Renate Kessler, Michael Fleischer, Christopher Springsguth, Marina Bigl, Jan-Peter Warnke, Klaus Eschrich. Prognostic Value of PFKFB3 to PFKFB4 mRNA Ratio in Patients With Primary Glioblastoma (IDH-Wildtype)Journal of Neuropathology & Experimental Neurology 2019; 78(9): 865 doi: 10.1093/jnen/nlz067
4
Shilpa Harshan, Poulami Dey, Srivatsan Raghunathan. Altered Transcriptional Regulation of Glycolysis in Circulating CD8+ T Cells of Rheumatoid Arthritis PatientsGenes 2022; 13(7): 1216 doi: 10.3390/genes13071216
5
Chang Liu, Ying Jin, Zhimin Fan. The Mechanism of Warburg Effect-Induced Chemoresistance in CancerFrontiers in Oncology 2021; 11 doi: 10.3389/fonc.2021.698023
6
Linlin Shi, Hongming Pan, Zhen Liu, Jiansheng Xie, Weidong Han. Roles of PFKFB3 in cancerSignal Transduction and Targeted Therapy 2017; 2(1) doi: 10.1038/sigtrans.2017.44
7
Krzysztof Kotowski, Jakub Rosik, Filip Machaj, Stanisław Supplitt, Daniel Wiczew, Karolina Jabłońska, Emilia Wiechec, Saeid Ghavami, Piotr Dzięgiel. Role of PFKFB3 and PFKFB4 in Cancer: Genetic Basis, Impact on Disease Development/Progression, and Potential as Therapeutic TargetsCancers 2021; 13(4): 909 doi: 10.3390/cancers13040909
8
Xiaoli Li, Jian Liu, Li Qian, Honggang Ke, Chan Yao, Wei Tian, Yifei Liu, Jianguo Zhang. Expression of PFKFB3 and Ki67 in lung adenocarcinomas and targeting PFKFB3 as a therapeutic strategyMolecular and Cellular Biochemistry 2018; 445(1-2): 123 doi: 10.1007/s11010-017-3258-8
9
Xinyu Gu, Jun Guan, Jia Xu, Qiuxian Zheng, Chao Chen, Qin Yang, Chunhong Huang, Gang Wang, Haibo Zhou, Zhi Chen, Haihong Zhu. Model based on five tumour immune microenvironment-related genes for predicting hepatocellular carcinoma immunotherapy outcomesJournal of Translational Medicine 2021; 19(1) doi: 10.1186/s12967-020-02691-4
10
Ramon Bartrons, Helga Simon-Molas, Ana Rodríguez-García, Esther Castaño, Àurea Navarro-Sabaté, Anna Manzano, Ubaldo E. Martinez-Outschoorn. Fructose 2,6-Bisphosphate in Cancer Cell MetabolismFrontiers in Oncology 2018; 8 doi: 10.3389/fonc.2018.00331
11
Lulu Lv, Ruo han Huang, Jiale Li, Jing Xu, Wen Gao. Impact of NSCLC metabolic remodeling on immunotherapy effectivenessBiomarker Research 2022; 10(1) doi: 10.1186/s40364-022-00412-1
12
Astrid A. Glück, Eleonora Orlando, Dominic Leiser, Michaela Poliaková, Lluís Nisa, Aurélie Quintin, Jacopo Gavini, Deborah M. Stroka, Sabina Berezowska, Lukas Bubendorf, Andree Blaukat, Daniel M. Aebersold, Michaela Medová, Yitzhak Zimmer. Identification of a MET-eIF4G1 translational regulation axis that controls HIF-1α levels under hypoxiaOncogene 2018; 37(30): 4181 doi: 10.1038/s41388-018-0256-6
13
Wei Wang, Bin Wang. KDM3A-mediated SP1 activates PFKFB4 transcription to promote aerobic glycolysis in osteosarcoma and augment tumor developmentBMC Cancer 2022; 22(1) doi: 10.1186/s12885-022-09636-8
14
Tugba H. Altunok, Robertino J. Muchut, Alberto A. Iglesias, Abdullah Yalcin. Transforming growth factor β1 upregulates 6‐phosphofructo‐2‐kinase/fructose 2,6‐bisphosphatase‐4 expression in A549 and MCF‐10A cellsCell Biochemistry and Function 2023; 41(8): 1220 doi: 10.1002/cbf.3856
15
Xiaojing Deng, Dapeng Li, Xiquan Ke, Qizhi Wang, Shanjun Yan, Yongju Xue, Qiangwu Wang, Hailun Zheng. Mir‐488 alleviates chemoresistance and glycolysis of colorectal cancer by targeting PFKFB3Journal of Clinical Laboratory Analysis 2021; 35(1) doi: 10.1002/jcla.23578
16
Ran Duan, Xiao Liang, Bangda Chai, Yiwen Zhou, Hengyu Du, Yingjun Suo, Zhaohuan Chen, Qingfeng Li, Xiaolu Huang. Isorhamnetin Induces Melanoma Cell Apoptosis via the PI3K/Akt and NF-κB PathwaysBioMed Research International 2020; 2020: 1 doi: 10.1155/2020/1057943
17
Fang Peng, Qiang Li, Jia-Yuan Sun, Ying Luo, Ming Chen, Yong Bao. PFKFB3 is involved in breast cancer proliferation, migration, invasion and angiogenesisInternational Journal of Oncology 2018;  doi: 10.3892/ijo.2018.4257
18
Selahattin C. Ozcan, Aybike Sarioglu, Tugba H. Altunok, Ahmet Akkoc, Saime Guzel, Sabire Guler, Yoannis Imbert-Fernandez, Robertino J. Muchut, Alberto A. Iglesias, Yunus Gurpinar, Amy L. Clem, Jason A. Chesney, Abdullah Yalcin. PFKFB2 regulates glycolysis and proliferation in pancreatic cancer cellsMolecular and Cellular Biochemistry 2020; 470(1-2): 115 doi: 10.1007/s11010-020-03751-5
19
Matias Estaras, Antonio Gonzalez. Modulation of cell physiology under hypoxia in pancreatic cancerWorld Journal of Gastroenterology 2021; 27(28): 4582-4602 doi: 10.3748/wjg.v27.i28.4582
20
Melissa Campos, Lauren V. Albrecht. Hitting the Sweet Spot: How Glucose Metabolism Is Orchestrated in Space and Time by Phosphofructokinase-1Cancers 2023; 16(1): 16 doi: 10.3390/cancers16010016
21
Brandon C. Jones, Paula R. Pohlmann, Robert Clarke, Surojeet Sengupta. Treatment against glucose-dependent cancers through metabolic PFKFB3 targeting of glycolytic fluxCancer and Metastasis Reviews 2022; 41(2): 447 doi: 10.1007/s10555-022-10027-5
22
Jiguang Meng, Xuxin Chen, Zhihai Han. PFKFB4 promotes lung adenocarcinoma progression via phosphorylating and activating transcriptional coactivator SRC-2BMC Pulmonary Medicine 2021; 21(1) doi: 10.1186/s12890-021-01420-x
23
Mahdi Bagheri, Safieh Aghaabdollahian, Milad Asghardoust Rezaei, Ali Mehdi Gholian Kholerdi, Mehdi Raei, Mohammad Keyvanloo Shahrestanaki. Overexpression of Long Non-coding RNAs MCM3AP-AS1 and LINC00092 Predict Poor Prognosis in Patients with Gastric AdenocarcinomaAdvanced Biomedical Research 2024; 13(1) doi: 10.4103/abr.abr_308_23
24
ZiYang Wang, ZhangCheng Ding, Qin-Han Xu, Jing-Xia Liu. Metabolism responses to silver nanoparticles stresses during zebrafish embryogenesisChemosphere 2019; 222: 991 doi: 10.1016/j.chemosphere.2019.01.177
25
Peiyu Liu, Dandan Sun, Shuchang Zhang, Shimei Chen, Xiaoqian Wang, Huiming Li, Fang Wei. PFKFB3 in neovascular eye disease: unraveling mechanisms and exploring therapeutic strategiesCell & Bioscience 2024; 14(1) doi: 10.1186/s13578-024-01205-9
26
Yinrui Lei, Tao Chen, Yeyi Li, Man Shang, Yan Zhang, Yuepeng Jin, Qiujing Yu, Fang Guo, Ting Wang. O-GlcNAcylation of PFKFB3 is required for tumor cell proliferation under hypoxiaOncogenesis 2020; 9(2) doi: 10.1038/s41389-020-0208-1
27
A. Marcell Szász, András Lánczky, Ádám Nagy, Susann Förster, Kim Hark, Jeffrey E. Green, Alex Boussioutas, Rita Busuttil, András Szabó, Balázs Győrffy. Cross-validation of survival associated biomarkers in gastric cancer using transcriptomic data of 1,065 patientsOncotarget 2016; 7(31): 49322 doi: 10.18632/oncotarget.10337
28
Hao Wu, Mengdi Fu, Mengwei Wu, Zhen Cao, Qiyao Zhang, Ziwen Liu. Emerging mechanisms and promising approaches in pancreatic cancer metabolismCell Death & Disease 2024; 15(8) doi: 10.1038/s41419-024-06930-0
29
Lidong Cao, Jiacheng Wu, Xianzhi Qu, Jiyao Sheng, Mengying Cui, Shui Liu, Xu Huang, Yien Xiang, Bingjin Li, Xuewen Zhang, Ranji Cui. Glycometabolic rearrangements--aerobic glycolysis in pancreatic cancer: causes, characteristics and clinical applicationsJournal of Experimental & Clinical Cancer Research 2020; 39(1) doi: 10.1186/s13046-020-01765-x
30
Yuwares Malila, Krittaporn Thanatsang, Sopacha Arayamethakorn, Tanaporn Uengwetwanit, Yanee Srimarut, Massimiliano Petracci, Gale M. Strasburg, Wanilada Rungrassamee, Wonnop Visessanguan, Stefan Wölfl. Absolute expressions of hypoxia-inducible factor-1 alpha (HIF1A) transcript and the associated genes in chicken skeletal muscle with white striping and wooden breast myopathiesPLOS ONE 2019; 14(8): e0220904 doi: 10.1371/journal.pone.0220904
31
Pei Du, Ren Guo, Keqin Gao, Shuang Yang, Baige Yao, Haobo Cui, Ming Zhao, Sujie Jia. Identification of differentially expressed genes and the role of PDK4 in CD14+ monocytes of coronary artery diseaseBioscience Reports 2021; 41(4) doi: 10.1042/BSR20204124
32
Jiao Feng, Jingjing Li, Liwei Wu, Qiang Yu, Jie Ji, Jianye Wu, Weiqi Dai, Chuanyong Guo. Emerging roles and the regulation of aerobic glycolysis in hepatocellular carcinomaJournal of Experimental & Clinical Cancer Research 2020; 39(1) doi: 10.1186/s13046-020-01629-4
33
Wanyuan Chen, Xiaolin Ye, Yun Chen, Tongwei Zhao, Hongying Zhou. M6A methylation of FKFB3 reduced pyroptosis of gastric cancer by NLRP3Anti-Cancer Drugs 2024; 35(4): 344 doi: 10.1097/CAD.0000000000001574
34
Pegah Farhadi, Reza Yarani, Sadat Dokaneheifard, Kamran Mansouri. The emerging role of targeting cancer metabolism for cancer therapyTumor Biology 2020; 42(10): 101042832096528 doi: 10.1177/1010428320965284
35
Javad Alizadeh, Mahboubeh Kavoosi, Navjit Singh, Shahrokh Lorzadeh, Amir Ravandi, Biniam Kidane, Naseer Ahmed, Fatima Mraiche, Michael R. Mowat, Saeid Ghavami. Regulation of Autophagy via Carbohydrate and Lipid Metabolism in CancerCancers 2023; 15(8): 2195 doi: 10.3390/cancers15082195
36
N. S. Shevchenko, N. V. Krutenko, T. V. Zimnytska, K. V. Voloshyn. The role of hypoxia-inducible factors in the development of chronic pathologyThe Ukrainian Biochemical Journal 2021; 93(4): 18 doi: 10.15407/ubj93.04.018
37
Jinshou Yang, Bo Ren, Gang Yang, Huanyu Wang, Guangyu Chen, Lei You, Taiping Zhang, Yupei Zhao. The enhancement of glycolysis regulates pancreatic cancer metastasisCellular and Molecular Life Sciences 2020; 77(2): 305 doi: 10.1007/s00018-019-03278-z
38
Akanksha Kashyap, Sheikh Mohammad Umar, Arundhathi Dev J. R., Sandeep R. Mathur, Ajay Gogia, Atul Batra, S. V. S. Deo, Chandra Prakash Prasad. Combination of 3PO analog PFK15 and siPFKL efficiently suppresses the migration, colony formation ability, and PFK‐1 activity of triple‐negative breast cancers by reducing the glycolysisJournal of Cellular Biochemistry 2023; 124(9): 1259 doi: 10.1002/jcb.30443
39
Yangdong Wu, Qingyan Kou, Lin Sun, Xiao Hu. Effects of anoxic prognostic model on immune microenvironment in pancreatic cancerScientific Reports 2023; 13(1) doi: 10.1038/s41598-023-36413-9
40
Lingmin Zhao, Di Ma, LiJuan Wang, XingQi Su, LiangShu Feng, LiChong Zhu, Ying Chen, YuLei Hao, XinYu Wang, JiaChun Feng. Metabolic changes with the occurrence of atherosclerotic plaques and the effects of statinsFrontiers in Immunology 2023; 14 doi: 10.3389/fimmu.2023.1301051
41
Zhong Zhang, Hai-Jun Zhang. Glycometabolic rearrangements–aerobic glycolysis in pancreatic ductal adenocarcinoma (PDAC): roles, regulatory networks, and therapeutic potentialExpert Opinion on Therapeutic Targets 2021; 25(12): 1077 doi: 10.1080/14728222.2021.2015321
42
Qiong Chen, Yang Liu, Yunxuan Zhu, Ziyan Zhu, Jueyao Zou, Yanhong Pan, Yin Lu, Wenxing Chen. Cryptotanshinone inhibits PFK-mediated aerobic glycolysis by activating AMPK pathway leading to blockade of cutaneous melanomaChinese Medicine 2024; 19(1) doi: 10.1186/s13020-024-00913-1
43
Prabhu Thirusangu, Upasana Ray, Sayantani Sarkar Bhattacharya, Derek B. Oien, Ling Jin, Julie Staub, Nagarajan Kannan, Julian R. Molina, Viji Shridhar. PFKFB3 regulates cancer stemness through the hippo pathway in small cell lung carcinomaOncogene 2022; 41(33): 4003 doi: 10.1038/s41388-022-02391-x
44
Wei Wang, Lijiang Zhou, Zheng Li, Guanhong Lin. Circ_0014130 is involved in the drug sensitivity of colorectal cancer through miR‐197‐3p/PFKFB3 axisJournal of Gastroenterology and Hepatology 2022; 37(5): 908 doi: 10.1111/jgh.15829
45
Ana Sara Gomes, Helena Ramos, Joana Soares, Lucília Saraiva. p53 and glucose metabolism: an orchestra to be directed in cancer therapyPharmacological Research 2018; 131: 75 doi: 10.1016/j.phrs.2018.03.015
46
Qiangqiang Zhao, Jian Li, Bin Wu, Yinghui Shang, Xueyuan Huang, Hang Dong, Haiting Liu, Wansong Chen, Rong Gui, Xinmin Nie. Smart Biomimetic Nanocomposites Mediate Mitochondrial Outcome through Aerobic Glycolysis Reprogramming: A Promising Treatment for LymphomaACS Applied Materials & Interfaces 2020; 12(20): 22687 doi: 10.1021/acsami.0c05763
47
Qian Long, Xuejing Zou, Yang Song, Zhijiao Duan, Li Liu. PFKFB3/HIF-1α feedback loop modulates sorafenib resistance in hepatocellular carcinoma cellsBiochemical and Biophysical Research Communications 2019; 513(3): 642 doi: 10.1016/j.bbrc.2019.03.109
48
Min-Chieh Hsin, Yi-Hsien Hsieh, Yi-Hsuan Hsiao, Pei-Ni Chen, Po-Hui Wang, Shun-Fa Yang. Carbonic Anhydrase IX Promotes Human Cervical Cancer Cell Motility by Regulating PFKFB4 ExpressionCancers 2021; 13(5): 1174 doi: 10.3390/cancers13051174
49
Liying Sha, Zhiqiang Lv, Yujun Liu, Yun Zhang, Xin Sui, Teng Wang, Hui Zhang. Shikonin inhibits the Warburg effect, cell proliferation, invasion and migration by downregulating PFKFB2 expression in lung cancerMolecular Medicine Reports 2021; 24(2) doi: 10.3892/mmr.2021.12199
50
Jiahua Xing, Ziqi Jia, Yichi Xu, Muzi Chen, Zheng Yang, Youbai Chen, Yan Han. KLF9 (Kruppel Like Factor 9) induced PFKFB3 (6-Phosphofructo-2-Kinase/Fructose-2, 6-Biphosphatase 3) downregulation inhibits the proliferation, metastasis and aerobic glycolysis of cutaneous squamous cell carcinoma cellsBioengineered 2021; 12(1): 7563 doi: 10.1080/21655979.2021.1980644
51
Erika Zodda, Olga Tura-Ceide, Nicholas L Mills, Josep Tarragó-Celada, Marina Carini, Timothy M Thomson, Marta Cascante. Autonomous metabolic reprogramming and oxidative stress characterize endothelial dysfunction in acute myocardial infarctioneLife 2023; 12 doi: 10.7554/eLife.86260
52
Méghane Sittewelle, Vincent Kappès, Chenxi Zhou, Déborah Lécuyer, Anne H Monsoro-Burq. PFKFB4 interacts with ICMT and activates RAS/AKT signaling-dependent cell migration in melanomaLife Science Alliance 2022; 5(12): e202201377 doi: 10.26508/lsa.202201377
53
Wei Zhu, Liang Ye, Jianzhao Zhang, Pengfei Yu, Hongbo Wang, Zuguang Ye, Jingwei Tian, Irina V Lebedeva. PFK15, a Small Molecule Inhibitor of PFKFB3, Induces Cell Cycle Arrest, Apoptosis and Inhibits Invasion in Gastric CancerPLOS ONE 2016; 11(9): e0163768 doi: 10.1371/journal.pone.0163768