For: | Han KQ, Huang G, Gu W, Su YH, Huang XQ, Ling CQ. Anti-tumor activities and apoptosis-regulated mechanisms of bufalin on the orthotopic transplantation tumor model of human hepatocellular carcinoma in nude mice. World J Gastroenterol 2007; 13(24): 3374-3379 [PMID: 17659679 DOI: 10.3748/wjg.v13.i24.3374] |
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URL: | https://www.wjgnet.com/1007-9327/full/v13/i24/3374.htm |
Number | Citing Articles |
1 |
Yu‑Long Lan, Jia‑Cheng Lou, Xue‑Wen Jiang, Xun Wang, Jin‑Shan Xing, Shao Li, Bo Zhang. A research update on the anticancer effects of bufalin and its derivatives (Review). Oncology Letters 2019; doi: 10.3892/ol.2019.10062
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2 |
Jorge A. R. Salvador, João F. S. Carvalho, Marco A. C. Neves, Samuel M. Silvestre, Alcino J. Leitão, M. Manuel C. Silva, M. Luisa Sá e Melo. Anticancer steroids: linking natural and semi-synthetic compounds. Nat. Prod. Rep. 2013; 30(2): 324 doi: 10.1039/C2NP20082A
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3 |
En-Yun Su, Yung-Lin Chu, Fu-Shin Chueh, Yi-Shih Ma, Shu-Fen Peng, Wen-Wen Huang, Ching-Lung Liao, An-Cheng Huang, Jing-Gung Chung. Bufalin Induces Apoptotic Cell Death in Human Nasopharyngeal Carcinoma Cells through Mitochondrial ROS and TRAIL Pathways. The American Journal of Chinese Medicine 2019; 47(01): 237 doi: 10.1142/S0192415X19500125
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4 |
Lívia Queiroz de Sousa, Kátia da Conceição Machado, Samara Ferreira de Carvalho Oliveira, Lidiane da Silva Araújo, Evaldo dos Santos Monção-Filho, Ana Amélia de Carvalho Melo-Cavalcante, Gerardo Magela Vieira-Júnior, Paulo Michel Pinheiro Ferreira. Bufadienolides from amphibians: A promising source of anticancer prototypes for radical innovation, apoptosis triggering and Na+/K+-ATPase inhibition. Toxicon 2017; 127: 63 doi: 10.1016/j.toxicon.2017.01.004
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5 |
Laura Soumoy, Ghanem E. Ghanem, Sven Saussez, Fabrice Journe. Bufalin for an innovative therapeutic approach against cancer. Pharmacological Research 2022; 184: 106442 doi: 10.1016/j.phrs.2022.106442
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6 |
Hsin-Yu Ho, Mu-Kuan Chen, Chia-Chieh Lin, Yu-Sheng Lo, Yi-Ching Chuang, Ming-Ju Hsieh. Arenobufagin induces cell apoptosis by modulating the cell cycle regulator claspin and the JNK pathway in nasopharyngeal carcinoma cells. Expert Opinion on Therapeutic Targets 2024; 28(5): 461 doi: 10.1080/14728222.2024.2348014
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7 |
Fang‐Jie Li, Jing‐Hong Hu, Xin Ren, Cheng‐Mei Zhou, Qian Liu, Yong‐Qing Zhang. Toad venom: A comprehensive review of chemical constituents, anticancer activities, and mechanisms. Archiv der Pharmazie 2021; 354(7) doi: 10.1002/ardp.202100060
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8 |
Xia Sheng, Xiaoting Sun, Kang Sun, Hua Sui, Jianmin Qin, Qi Li. Inhibitory effect of bufalin combined with Hedgehog signaling pathway inhibitors on proliferation and invasion and metastasis of liver cancer cells. International Journal of Oncology 2016; 49(4): 1513 doi: 10.3892/ijo.2016.3667
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9 |
Waqas Alam, Imad Ahmad, Michael Aschner, Haroon Khan. Phytonutrients in the Treatment of Gastrointestinal Cancer. 2023; : 109 doi: 10.2174/9789815049633123010008
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10 |
Jude I. Ayogu, Amaechi S. Odoh. Prospects and Therapeutic Applications of Cardiac Glycosides in Cancer Remediation. ACS Combinatorial Science 2020; 22(11): 543 doi: 10.1021/acscombsci.0c00082
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11 |
Gang Pan, Yi-jie Bao, Jie Xu, Tao Liu, Cheng Liu, Yan-yan Qiu, Xiao-jing Shi, Hui Yu, Ting-ting Jia, Xia Yuan, Ze-ting Yuan, Pei-hao Yin, Yi-jun Cao. Esterase-responsive polymeric prodrug-based tumor targeting nanoparticles for improved anti-tumor performance against colon cancer. RSC Advances 2016; 6(48): 42109 doi: 10.1039/C6RA05236C
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12 |
Ailiang Chen, Jian Yu, Liang Zhang, Yimin Sun, Yan Zhang, Hongyan Guo, Yuxiang Zhou, Keith Mitchelson, Jing Cheng. Microarray and biochemical analysis of bufalin-induced apoptosis of HL-60 Cells. Biotechnology Letters 2009; 31(4): 487 doi: 10.1007/s10529-008-9888-x
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13 |
Xiao-feng Zhai, Fan-fu Fang, Qun Liu, Yong-bin Meng, Yu-yu Guo, Zhe Chen. MiR-181a contributes to bufalin-induced apoptosis in PC-3 prostate cancer cells. BMC Complementary and Alternative Medicine 2013; 13(1) doi: 10.1186/1472-6882-13-325
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14 |
Dongdong Yang, Ping Gao, Chao Tian, Yang Sheng. Gompertz tracking of the growth trajectories of the human-liver-cancer xenograft-tumors in nude mice. Computer Methods and Programs in Biomedicine 2020; 191: 105412 doi: 10.1016/j.cmpb.2020.105412
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15 |
Chien-shan Cheng, Jiaqiang Wang, Jie Chen, Kuei Ting Kuo, Jian Tang, Huifeng Gao, Lianyu Chen, Zhen Chen, Zhiqiang Meng. New therapeutic aspects of steroidal cardiac glycosides: the anticancer properties of Huachansu and its main active constituent Bufalin. Cancer Cell International 2019; 19(1) doi: 10.1186/s12935-019-0806-1
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16 |
He Huang, Yang Cao, Wei Wei, Wei Liu, Shao-Yong Lu, Yu-Bao Chen, Yan Wang, Hua Yan, Ying-Li Wu, Ferenc Gallyas. Targeting Poly (ADP-Ribose) Polymerase Partially Contributes to Bufalin-Induced Cell Death in Multiple Myeloma Cells. PLoS ONE 2013; 8(6): e66130 doi: 10.1371/journal.pone.0066130
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17 |
Min-ji Choi, Ka-na Kim, Jae-Eun Lee, Jin-Woo Suh, Sung- Chul Kim, Ki Rok Kwon, Seung-Hun Cho. Effects of Sumsu (Bufonis venenum) Pharmacopuncture Treatment on Depression in Mice. Journal of Pharmacopuncture 2014; 17(2): 27 doi: 10.3831/KPI.2014.17.013
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18 |
Tatjana Mijatovic, Laurent Ingrassia, Vincenzo Facchini, Robert Kiss. Na+/K+-ATPase α subunits as new targets in anticancer therapy. Expert Opinion on Therapeutic Targets 2008; 12(11): 1403 doi: 10.1517/14728222.12.11.1403
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19 |
Ching‐Han Yu, Shu‐Fen Kan, Hsiao‐Fung Pu, Eileen Jea Chien, Paulus S. Wang. Apoptotic signaling in bufalin‐ and cinobufagin‐treated androgen‐dependent and ‐independent human prostate cancer cells. Cancer Science 2008; 99(12): 2467 doi: 10.1111/j.1349-7006.2008.00966.x
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20 |
Katharina Schimmel, Mira Jung, Ariana Foinquinos, Gorka San José, Javier Beaumont, Katharina Bock, Lea Grote-Levi, Ke Xiao, Christian Bär, Angelika Pfanne, Annette Just, Karina Zimmer, Soeun Ngoy, Begoña López, Susana Ravassa, Sabine Samolovac, Heike Janssen-Peters, Janet Remke, Kristian Scherf, Seema Dangwal, Maria-Teresa Piccoli, Felix Kleemiss, Fabian Philipp Kreutzer, Franziska Kenneweg, Julia Leonardy, Lisa Hobuß, Laura Santer, Quoc-Tuan Do, Robert Geffers, Jan Hinrich Braesen, Jessica Schmitz, Christina Brandenberger, Dominik N. Müller, Nicola Wilck, Volkhard Kaever, Heike Bähre, Sandor Batkai, Jan Fiedler, Kevin M. Alexander, Bradley M. Wertheim, Sudeshna Fisch, Ronglih Liao, Javier Diez, Arantxa González, Thomas Thum. Natural Compound Library Screening Identifies New Molecules for the Treatment of Cardiac Fibrosis and Diastolic Dysfunction. Circulation 2020; 141(9): 751 doi: 10.1161/CIRCULATIONAHA.119.042559
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21 |
Yu-Ping Hsiao, Chun-Shu Yu, Chien-Chih Yu, Jai-Sing Yang, Jo-Hua Chiang, Chi-Cheng Lu, Hui-Ying Huang, Nou-Ying Tang, Jen-Hung Yang, An-Cheng Huang, Jing-Gung Chung. Triggering Apoptotic Death of Human Malignant Melanoma A375.S2 Cells by Bufalin: Involvement of Caspase Cascade-Dependent and Independent Mitochondrial Signaling Pathways. Evidence-Based Complementary and Alternative Medicine 2012; 2012: 1 doi: 10.1155/2012/591241
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22 |
Wanlu Zhao, Guihuan Li, Qianbing Zhang, Meixuan Chen, Lijun He, Zhicong Wu, Yihe Zhang, Mingming Fan, Yanling Liang, Wenlong Zhang, Fangyin Zeng, Fan Deng. Cardiac glycoside neriifolin exerts anti-cancer activity in prostate cancer cells by attenuating DNA damage repair through endoplasmic reticulum stress. Biochemical Pharmacology 2023; 209: 115453 doi: 10.1016/j.bcp.2023.115453
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23 |
Li-pei Wang, Yan-na Zhao, Xin Sun, Rui-lan Gao. Effects of bufalin on up-regulating methylation of Wilm’s tumor 1 gene in human erythroid leukemic cells. Chinese Journal of Integrative Medicine 2017; 23(4): 288 doi: 10.1007/s11655-017-2404-1
|
24 |
Yinhui Dong, Shutao Yin, Jinghua Li, Cheng Jiang, Min Ye, Hongbo Hu. Bufadienolide compounds sensitize human breast cancer cells to TRAIL-induced apoptosis via inhibition of STAT3/Mcl-1 pathway. Apoptosis 2011; 16(4): 394 doi: 10.1007/s10495-011-0573-5
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25 |
Angellica Fernandes de OLIVEIRA, Lindsey CASTOLDI, Gerardo Magela VIEIRA JUNIOR, Evaldo dos Santos MONÇÃO FILHO, Mariana Helena CHAVES, Domingos de Jesus RODRIGUES, Marina Mariko SUGUI. Evaluation of antimutagenic and cytotoxic activity of skin secretion extract of Rhinella marina and Rhaebo guttatus (Anura, Bufonidae). Acta Amazonica 2019; 49(2): 145 doi: 10.1590/1809-4392201801751
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26 |
Xin Tian, Shundong Dai, Jing Sun, Shenyi Jiang, Chengguang Sui, Fandong Meng, Yan Li, Liye Fu, Tao Jiang, Yang Wang, Jia Su, Youhong Jiang. Bufalin Induces Mitochondria-Dependent Apoptosis in Pancreatic and Oral Cancer Cells by Downregulating hTERT Expression via Activation of the JNK/p38 Pathway. Evidence-Based Complementary and Alternative Medicine 2015; 2015: 1 doi: 10.1155/2015/546210
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27 |
Guangli Li, Tianyue An, Yu Li, Jinyang Yue, Ruoshi Huang, Jia Huang, Jincai Liang, Wei Yao, Liufang Huang, Yidu Chen, Rongrong Zhang, Aijia Ji, Lixin Duan. Transcriptome Analysis and Identification of the Cholesterol Side Chain Cleavage Enzyme BbgCYP11A1 From Bufo bufo gargarizans. Frontiers in Genetics 2022; 13 doi: 10.3389/fgene.2022.828877
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28 |
Shin‐Hwar Wu, Da‐Tian Bau, Yung‐Ting Hsiao, Kung‐Wen Lu, Te‐Chun Hsia, Jin‐Cherng Lien, Yang‐Ching Ko, Wu‐Huei Hsu, Su‐Tso Yang, Yi‐Ping Huang, Jing‐Gung Chung. Bufalin induces apoptosis in vitro and has Antitumor activity against human lung cancer xenografts in vivo. Environmental Toxicology 2017; 32(4): 1305 doi: 10.1002/tox.22325
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29 |
Xia Sheng, Pengfei Zhu, Yi Zhao, Jinwei Zhang, Haijia Li, Huan Zhao, Jianmin Qin. Effect of PI3K/AKT/mTOR Signaling Pathway on Regulating and Controlling the Anti-Invasion and Metastasis of Hepatoma Cells by Bufalin. Recent Patents on Anti-Cancer Drug Discovery 2021; 16(1): 54 doi: 10.2174/1574892816666210201120324
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30 |
Ji Qi, Abu Hasanat Md Zulfiker, Chun Li, David Good, Ming Q. Wei. The Development of Toad Toxins as Potential Therapeutic Agents. Toxins 2018; 10(8): 336 doi: 10.3390/toxins10080336
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31 |
Chuang-xin Lu, Wen-yu Wang, Ning Ma, Yao Cui, Xiao-yan Li, Yun Zhou. Anticancer peptide from Chinese toad (Bufo Bufo Gargarizans) skin enhanced sensitivity to 5-Fu in hepatocarcinoma cells (HepG2). Clinical Oncology and Cancer Research 2011; 8(3): 149 doi: 10.1007/s11805-011-0574-8
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32 |
Ya-Yin Chen, Hsu-Feng Lu, Shu-Chun Hsu, Chao-Lin Kuo, Shu-Jen Chang, Jen-Jyh Lin, Ping-Ping Wu, Jia-You Liu, Ching-Hsiao Lee, Jing-Gung Chung, Jin-Biou Chang. Bufalin inhibits migration and invasion in human hepatocellular carcinoma SK-Hep1 cells through the inhibitions of NF-kB and matrix metalloproteinase-2/-9-signaling pathways. Environmental Toxicology 2015; 30(1): 74 doi: 10.1002/tox.21896
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33 |
Yi-Ze Zhang, Xi Chen, Xing-Xing Fan, Jian-Xing He, Jun Huang, Da-Kai Xiao, Yan-Ling Zhou, Sen-You Zheng, Jia-Hui Xu, Xiao-Jun Yao, Liang Liu, Elaine Leung. Compound Library Screening Identified Cardiac Glycoside Digitoxin as an Effective Growth Inhibitor of Gefitinib-Resistant Non-Small Cell Lung Cancer via Downregulation of α-Tubulin and Inhibition of Microtubule Formation. Molecules 2016; 21(3): 374 doi: 10.3390/molecules21030374
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34 |
Hosam A Elbaz, Todd A Stueckle, William Tse, Yon Rojanasakul, Cerasela Zoica Dinu. Digitoxin and its analogs as novel cancer therapeutics. Experimental Hematology & Oncology 2012; 1(1) doi: 10.1186/2162-3619-1-4
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35 |
Yong Pan, Patrea Rhea, Lin Tan, Carrie Cartwright, Ho-Jeong Lee, Murali K. Ravoori, Crandell Addington, Mihai Gagea, Vikas Kundra, Sun-Jin Kim, Robert A. Newman, Peiying Yang. PBI-05204, a supercritical CO2 extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway. Investigational New Drugs 2015; 33(2): 271 doi: 10.1007/s10637-014-0190-6
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36 |
Yaohan Wang, Li Feng, Bingkui Piao, Peitong Zhang, Shuang-En Chuang. Review on Research about Traditional Chinese Medicine in Cancer Stem Cell. Evidence-Based Complementary and Alternative Medicine 2017; 2017(1) doi: 10.1155/2017/4505194
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37 |
Han-Yu Chou, Fu-Shin Chueh, Yi-Shih Ma, Rick Sai-Chuen Wu, Ching-Lung Liao, Yung-Lin Chu, Ming-Jen Fan, Wen-Wen Huang, Jing-Gung Chung. Bufalin induced apoptosis in SCC-4 human tongue cancer cells by decreasing Bcl-2 and increasing Bax expression via the mitochondria-dependent pathway. Molecular Medicine Reports 2017; 16(6): 7959 doi: 10.3892/mmr.2017.7651
|
38 |
Huang Houbao, Zhang Wei. Bufalin induced apoptosis of bladder carcinoma cells through the inactivation of Na+K+‑ATPase. Oncology Letters 2018; doi: 10.3892/ol.2018.9142
|
39 |
Shin-Hwar Wu, Tzu-Yun Wu, Yung-Ting Hsiao, Ju-Hwa Lin, Shu-Chun Hsu, Te-Chun Hsia, Su-Tso Yang, Wu-Huei Hsu, Jing-Gung Chung. Bufalin Induces Cell Death in Human Lung Cancer Cells through Disruption of DNA Damage Response Pathways. The American Journal of Chinese Medicine 2014; 42(03): 729 doi: 10.1142/S0192415X14500475
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40 |
Yun-Rong Zhu, Yong Xu, Jian-Feng Fang, Feng Zhou, Xiong-Wei Deng, Yun-Qing Zhang. Bufotalin-induced apoptosis in osteoblastoma cells is associated with endoplasmic reticulum stress activation. Biochemical and Biophysical Research Communications 2014; 451(1): 112 doi: 10.1016/j.bbrc.2014.07.077
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41 |
Laetitia Moreno Y. Banuls, Ernst Urban, Michel Gelbcke, François Dufrasne, Brigitte Kopp, Robert Kiss, Martin Zehl. Structure–Activity Relationship Analysis of Bufadienolide-Induced in Vitro Growth Inhibitory Effects on Mouse and Human Cancer Cells. Journal of Natural Products 2013; 76(6): 1078 doi: 10.1021/np400034d
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42 |
Hesham R. El-Seedi, Nermeen Yosri, Bishoy El-Aarag, Shaymaa H. Mahmoud, Ahmed Zayed, Ming Du, Aamer Saeed, Syed G. Musharraf, Islam M. El-Garawani, Mohamed R. Habib, Haroon Elrasheid Tahir, Momtaz M. Hegab, Xiaobo Zou, Zhiming Guo, Thomas Efferth, Shaden A. M. Khalifa. Chemistry and the Potential Antiviral, Anticancer, and Anti-Inflammatory Activities of Cardiotonic Steroids Derived from Toads. Molecules 2022; 27(19): 6586 doi: 10.3390/molecules27196586
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43 |
Ioannis Prassas, Eleftherios P. Diamandis. Novel therapeutic applications of cardiac glycosides. Nature Reviews Drug Discovery 2008; 7(11): 926 doi: 10.1038/nrd2682
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44 |
Shin-Hwar Wu, Yung-Ting Hsiao, Jaw-Chyum Chen, Ju-Hwa Lin, Shu-Chun Hsu, Te-Chun Hsia, Su-Tso Yang, Wu-Huei Hsu, Jing-Gung Chung. Bufalin Alters Gene Expressions Associated DNA Damage, Cell Cycle, and Apoptosis in Human Lung Cancer NCI-H460 Cells in Vitro. Molecules 2014; 19(5): 6047 doi: 10.3390/molecules19056047
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45 |
T. O. Veklich, R. D. Labyntseva, O. A. Shkrabak, O. V. Tsymbalyuk, R. V. Rodik, V. I. Kalchenko, S. O. Kosterin. Inhibition of Na(+),K(+)-ATPase and activation of myosin ATPase by calix[4]arene C-107 cause stimulation of isolated smooth muscle contractile activity. The Ukrainian Biochemical Journal 2020; 92(1): 21 doi: 10.15407/ubj92.01.021
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46 |
Lina Gao, Lei Zhang, Fengjun He, Jing Chen, Meng Zhao, Simin Li, Hao Wu, Yumeng Liu, Yinan Zhang, Qineng Ping, Lihong Hu, Hongzhi Qiao. Surfactant Assisted Rapid-Release Liposomal Strategies Enhance the Antitumor Efficiency of Bufalin Derivative and Reduce Cardiotoxicity. International Journal of Nanomedicine 2021; : 3581 doi: 10.2147/IJN.S313153
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47 |
Rui Xue, Na Han, Chun Ye, Lihui Wang, Jingyu Yang, Yu Wang, Jun Yin. The cytotoxic activities of cardiac glycosides from Streptocaulon juventas and the structure–activity relationships. Fitoterapia 2014; 98: 228 doi: 10.1016/j.fitote.2014.08.008
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48 |
Fan Yang, Luo Zhuo, Sunnassee Ananda, Tingyi Sun, Shangxun Li, Liang Liu. Role of reactive oxygen species in triptolide-induced apoptosis of renal tubular cells and renal injury in rats. Journal of Huazhong University of Science and Technology [Medical Sciences] 2011; 31(3): 335 doi: 10.1007/s11596-011-0377-4
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49 |
Wei Gu, Fan-Fu Fang, Bai Li, Bin-Bin Cheng, Chang-Quan Ling. Characterization and Resistance Mechanisms of A 5-fluorouracil-resistant Hepatocellular Carcinoma Cell Line. Asian Pacific Journal of Cancer Prevention 2012; 13(9): 4807 doi: 10.7314/APJCP.2012.13.9.4807
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50 |
Hui-Chi Huang, Wen-Te Chang, Meng-Shiou Lee, Hsing-Yu Chen, Yu-Hua Chen, Chi-Chen Lin, Ming-Kuem Lin. Three bufadienolides induce cell death in the human lung cancer cell line CL1‐5 mainly through autophagy. Bioorganic & Medicinal Chemistry Letters 2021; 31: 127715 doi: 10.1016/j.bmcl.2020.127715
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51 |
Yuewen Chang, Yongfang Zhao, Hongsheng Zhan, Xiaoen Wei, Tianjin Liu, Bo Zheng. Bufalin inhibits the differentiation and proliferation of human osteosarcoma cell line hMG63-derived cancer stem cells. Tumor Biology 2014; 35(2): 1075 doi: 10.1007/s13277-013-1143-y
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52 |
Fan Yang, Liang Ren, Luo Zhuo, Sunnassee Ananda, Liang Liu. Involvement of oxidative stress in the mechanism of triptolide-induced acute nephrotoxicity in rats. Experimental and Toxicologic Pathology 2012; 64(7-8): 905 doi: 10.1016/j.etp.2011.03.013
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53 |
Noriyuki Takai, Naoko Kira, Terukazu Ishii, Toshie Yoshida, Masakazu Nishida, Yoshihiro Nishida, Kaei Nasu, Hisashi Narahara. Bufalin, a Traditional Oriental Medicine, Induces Apoptosis in Human Cancer Cells. Asian Pacific Journal of Cancer Prevention 2012; 13(1): 399 doi: 10.7314/APJCP.2012.13.1.399
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54 |
SHIH-CHANG TSAI, CHI-CHENG LU, CHAO-YING LEE, YUNG-CHANG LIN, JING-GUNG CHUNG, SHENG-CHU KUO, SAKAE AMAGAYA, FEI-NA CHEN, MICHAEL YUANCHIEN CHEN, SHIH-FENG CHAN, JAI-SING YANG. AKT serine/threonine protein kinase modulates bufalin-triggered intrinsic pathway of apoptosis in CAL 27 human oral cancer cells. International Journal of Oncology 2012; 41(5): 1683 doi: 10.3892/ijo.2012.1605
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55 |
Lei Sun, Tongsheng Chen, Xiaoping Wang, Yun Chen, Xunbin Wei. Bufalin Induces Reactive Oxygen Species Dependent Bax Translocation and Apoptosis in ASTC‐a‐1 Cells. Evidence-Based Complementary and Alternative Medicine 2011; 2011(1) doi: 10.1093/ecam/nep082
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56 |
EKEM T. EFUET, XIAO-PING DING, CARRIE CARTWRIGHT, YONG PAN, LORENZO COHEN, PEIYING YANG. Huachansu mediates cell death in non-Hodgkin’s lymphoma by induction of caspase-3 and inhibition of MAP kinase. International Journal of Oncology 2015; 47(2): 592 doi: 10.3892/ijo.2015.3044
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57 |
Lin Jiang, Ming-Ning Zhao, Tian-Yu Liu, Xiang-Song Wu, Hao Weng, Qian Ding, Yi-Jun Shu, Run-Fa Bao, Mao-Lan Li, Jia-Sheng Mu, Wen-Guang Wu, Qi-Chen Ding, Yang Cao, Yun-Ping Hu, Bai-Yong Shen, Zhu-Jun Tan, Ying-Bin Liu. Bufalin induces cell cycle arrest and apoptosis in gallbladder carcinoma cells. Tumor Biology 2014; 35(11): 10931 doi: 10.1007/s13277-014-1911-3
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58 |
Zhe Pan, Yunpeng Xie, Jie Bai, Qiuyue Lin, Xiaonan Cui, Ningning Zhang. Bufalin suppresses colorectal cancer cell growth through promoting autophagyin vivoandin vitro. RSC Advances 2018; 8(68): 38910 doi: 10.1039/C8RA06566G
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59 |
CHIN-MU HSU, YUHSIN TSAI, LEI WAN, FUU-JEN TSAI. Bufalin induces G2/M phase arrest and triggers autophagy via the TNF, JNK, BECN-1 and ATG8 pathway in human hepatoma cells. International Journal of Oncology 2013; 43(1): 338 doi: 10.3892/ijo.2013.1942
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60 |
Israel José Pereira Garcia, Gisele Capanema de Oliveira, Jéssica Martins de Moura Valadares, Felipe Finger Banfi, Silmara Nunes Andrade, Túlio Resende Freitas, Evaldo dos Santos Monção Filho, Hérica de Lima Santos, Gerardo Magela Vieira Júnior, Mariana Helena Chaves, Domingos de Jesus Rodrigues, Bruno Antonio Marinho Sanchez, Fernando P. Varotti, Leandro Augusto Barbosa. New bufadienolides extracted from Rhinella marina inhibit Na,K-ATPase and induce apoptosis by activating caspases 3 and 9 in human breast and ovarian cancer cells. Steroids 2019; 152: 108490 doi: 10.1016/j.steroids.2019.108490
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61 |
Laura Soumoy, Aline Genbauffe, Lena Mouchart, Alexandra Sperone, Anne Trelcat, Léa Mukeba-Harchies, Mathilde Wells, Bertrand Blankert, Ahmad Najem, Ghanem Ghanem, Sven Saussez, Fabrice Journe. ATP1A1 is a promising new target for melanoma treatment and can be inhibited by its physiological ligand bufalin to restore targeted therapy efficacy. Cancer Cell International 2024; 24(1) doi: 10.1186/s12935-023-03196-y
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62 |
Li-Juan Deng, Li-Ping Hu, Qun-Long Peng, Xiao-Lin Yang, Liang-Liang Bai, Anita Yiu, Yong Li, Hai-Yan Tian, Wen-Cai Ye, Dong-Mei Zhang. Hellebrigenin induces cell cycle arrest and apoptosis in human hepatocellular carcinoma HepG2 cells through inhibition of Akt. Chemico-Biological Interactions 2014; 219: 184 doi: 10.1016/j.cbi.2014.06.003
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63 |
Rong-Ping Zhou, Gang Chen, Zhi-Li Shen, Li-Qun Pan. Cinobufacin Suppresses Cell Proliferation via miR-494 in BGC-823 Gastric Cancer Cells. Asian Pacific Journal of Cancer Prevention 2014; 15(3): 1241 doi: 10.7314/APJCP.2014.15.3.1241
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64 |
Paulus S. Wang, Jiun-Yih Yeh, Ching-Han Yu, Shyi-Wu Wang. Evidence-based Anticancer Materia Medica. Evidence-based Anticancer Complementary and Alternative Medicine 2011; : 389 doi: 10.1007/978-94-007-0526-5_18
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65 |
Donghao Tang, Yuejiao Feng, Jiahao Lu, Linlin Jia, Dongxiao Shen, Jing Shang, Teng Chen, Peihao Yin, Jinbao Chen, Jie Wang. Global trends in bufalin application research for cancer from 2003 to 2022: A bibliometric and visualised analysis. Heliyon 2024; 10(2): e24395 doi: 10.1016/j.heliyon.2024.e24395
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66 |
Ying Liu, Pengfei Wang, Chen Sun, Nianping Feng, Wuxiong Zhou, Yang Yang, Rong Tan, Zhiqiang Chen, Shan Wu, Jihui Zhao. Wheat germ agglutinin-grafted lipid nanoparticles: Preparation and in vitro evaluation of the association with Caco-2 monolayers. International Journal of Pharmaceutics 2010; 397(1-2): 155 doi: 10.1016/j.ijpharm.2010.06.030
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67 |
Qian Wang, Ce Li, Zhitu Zhu, Yuee Teng, Xiaofang Che, Yan Wang, Yanju Ma, Yiding Wang, Huachuan Zheng, Yunpeng Liu, Xiujuan Qu. miR-155-5p antagonizes the apoptotic effect of bufalin in triple-negative breast cancer cells. Anti-Cancer Drugs 2016; 27(1): 9 doi: 10.1097/CAD.0000000000000296
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68 |
Wenpan Peng, Yong Xu, Fanchao Feng, Cheng Gu, Zhichao Wang, Di Han, Xianmei Zhou, Hailang He, Juntra Karbwang. Meta-Analysis of Therapy of Cinobufacini Capsule Adjunct with First-Line Platinum-Based Chemotherapy for the Treatment of Advanced NSCLC. Evidence-Based Complementary and Alternative Medicine 2021; 2021: 1 doi: 10.1155/2021/5596415
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69 |
Pei-Hao Yin, Xuan Liu, Yan-Yan Qiu, Jian-Feng Cai, Jian-Min Qin, Hui-Rong Zhu, Qi Li. Anti-tumor Activity and Apoptosis-regulation Mechanisms of Bufalin in Various Cancers: New Hope for Cancer Patients. Asian Pacific Journal of Cancer Prevention 2012; 13(11): 5339 doi: 10.7314/APJCP.2012.13.11.5339
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70 |
Hsiao-Ting Chen, David Sun, Yen-Chun Peng, Pu-Hong Kao, Yuh-Lin Wu. Novel augmentation by bufalin of protein kinase C-induced cyclooxygenase-2 and IL-8 production in human breast cancer cells. Innate Immunity 2017; 23(1): 54 doi: 10.1177/1753425916676347
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71 |
Ranjith Kumavath, Sayan Paul, Honey Pavithran, Manash K. Paul, Preetam Ghosh, Debmalya Barh, Vasco Azevedo. Emergence of Cardiac Glycosides as Potential Drugs: Current and Future Scope for Cancer Therapeutics. Biomolecules 2021; 11(9): 1275 doi: 10.3390/biom11091275
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72 |
Paulo Michel Pinheiro Ferreira, Lívia Queiroz de Sousa, Rayran Walter Ramos de Sousa, Domingos de Jesus Rodrigues, Evaldo dos Santos Monção Filho, Mariana Helena Chaves, Gerardo Magela Vieira Júnior, Márcia dos Santos Rizzo, Lívia Alves Filgueiras, Anderson Nogueira Mendes, Daisy Jereissati Barbosa Lima, Cláudia Pessoa, João Marcelo de Castro e Sousa, Ana Carolina Borges da Cruz Rodrigues, Milena Botelho Pereira Soares, Daniel Pereira Bezerra. Toxic profile of marinobufagin from poisonous Amazon toads and antitumoral effects on human colorectal carcinomas. Journal of Ethnopharmacology 2023; 310: 116406 doi: 10.1016/j.jep.2023.116406
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