For: | Stadlbauer V, Fickert P, Lackner C, Schmerlaib J, Krisper P, Trauner M, Stauber RE. Hepatotoxicity of NONI juice: Report of two cases. World J Gastroenterol 2005; 11(30): 4758-4760 [PMID: 16094725 DOI: 10.3748/wjg.v11.i30.4758] |
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URL: | https://www.wjgnet.com/1007-9327/full/v11/i30/4758.htm |
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Brett J West, C Jarakae Jensen, Johannes Westendorf. Noni juice is not hepatotoxic. World Journal of Gastroenterology 2006; 12(22): 3616-3619 doi: 10.3748/wjg.v12.i22.3616
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Gunda Millonig, Wolfgang Vogel. Reply. European Journal of Gastroenterology & Hepatology 2006; 18(5): 577 doi: 10.1097/00042737-200605000-00026
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Opinion of the Scientific Panel on Dietetic products, nutrition and allergies [NDA] related to the safety of noni juice (juice of the fruits of Morinda citrifolia). EFSA Journal 2006; 4(9) doi: 10.2903/j.efsa.2006.376
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Shixin Deng, Brett J. West, C. Jarakae Jensen, Simla Basar, Johannes Westendorf. Development and validation of an RP-HPLC method for the analysis of anthraquinones in noni fruits and leaves. Food Chemistry 2009; 116(2): 505 doi: 10.1016/j.foodchem.2009.02.070
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J. Hübner, C. Keinki, B. Zomorodbakhsch. Bedrohliche Situationen durch komplementäre und alternative Medizin. Der Onkologe 2020; 26(2): 169 doi: 10.1007/s00761-019-00699-0
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Rolf Teschke, Gaby Danan. Worldwide Use of RUCAM for Causality Assessment in 81,856 Idiosyncratic DILI and 14,029 HILI Cases Published 1993–Mid 2020: A Comprehensive Analysis. Medicines 2020; 7(10): 62 doi: 10.3390/medicines7100062
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James H Lewis, Moustafa Ahmed, Ahmed Shobassy, Caren Palese. Drug-induced liver disease. Current Opinion in Gastroenterology 2006; 22(3): 223 doi: 10.1097/01.mog.0000218958.40441.fd
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Opinion on the safety of Tahitian Noni® ‘Morinda citrifolia (noni) fruit puree and concentrate’ as a novel food ingredient. EFSA Journal 2009; 7(4) doi: 10.2903/j.efsa.2009.998
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11 |
Alisara Arirachakaran, Manusak Boonard, Kornkit Chaijenkij, Kwanchai Pituckanotai, Akom Prommahachai, Jatupon Kongtharvonskul. A systematic review and meta-analysis of diagnostic test of MRA versus MRI for detection superior labrum anterior to posterior lesions type II–VII. Skeletal Radiology 2017; 46(2): 149 doi: 10.1007/s00256-016-2525-1
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Aline Inada, Priscila Figueiredo, Rosângela Santos-Eichler, Karine Freitas, Priscila Hiane, Alinne Castro, Rita Guimarães. Morinda citrifolia Linn. (Noni) and Its Potential in Obesity-Related Metabolic Dysfunction. Nutrients 2017; 9(6): 540 doi: 10.3390/nu9060540
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Rainer W. Bussmann, Lothar Hennig, Athanassios Giannis, Jutta Ortwein, Toni M. Kutchan, Xi Feng. Anthraquinone Content in Noni (Morinda citrifoliaL.). Evidence-Based Complementary and Alternative Medicine 2013; 2013: 1 doi: 10.1155/2013/208378
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Xiaowei Huo, Simian Sun, Kexing Li, Jun Zhang, Yumeng Wang, Hongyu Gao, Zepeng Cao, Xudong Xu, Guoxu Ma, Mengmeng Liu. Constituent analysis, laxative activity, and toxicological evaluation of methanol extract of noni fruit (Morinda citrifolia L., Rubiaceae). Food Chemistry: X 2023; 20: 100925 doi: 10.1016/j.fochx.2023.100925
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Amy Christine Brown. Liver toxicity related to herbs and dietary supplements: Online table of case reports. Part 2 of 5 series. Food and Chemical Toxicology 2017; 107: 472 doi: 10.1016/j.fct.2016.07.001
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Alison D Pawlus, A Douglas Kinghorn. Review of the ethnobotany, chemistry, biological activity and safety of the botanical dietary supplement Morinda citrifolia (noni). Journal of Pharmacy and Pharmacology 2007; 59(12): 1587 doi: 10.1211/jpp.59.12.0001
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Genario Santos, Jessica Gasca, Raymundo Parana, Vinicius Nunes, Maria Schinnoni, Inmaculada Medina‐Caliz, Maria Rosario Cabello, Maria Isabel Lucena, Raul J. Andrade. Profile of herbal and dietary supplements induced liver injury in Latin America: A systematic review of published reports. Phytotherapy Research 2021; 35(1): 6 doi: 10.1002/ptr.6746
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Jasmina Dimitrova-Shumkovska, Leo Veenman, Trpe Ristoski, Svetlana Leschiner, Moshe Gavish. Decreases in Binding Capacity of the Mitochondrial 18 kDa Translocator Protein Accompany Oxidative Stress and Pathological Signs in Rat Liver After DMBA Exposure. Toxicologic Pathology 2010; 38(6): 957 doi: 10.1177/0192623310379137
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Sibylle Rademacher, Michael Oppert, Achim Jörres. Artificial extracorporeal liver support therapy in patients with severe liver failure. Expert Review of Gastroenterology & Hepatology 2011; 5(5): 591 doi: 10.1586/egh.11.59
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Madhukar Lohani, Mohammed Majrashi, Manoj Govindarajulu, Mansi Patel, Sindhu Ramesh, Dwipayan Bhattacharya, Sneha Joshi, Maali Fadan, Rishi Nadar, Benjamin Darien, Denzil V. Maurice, Barbara Kemppainen, Muralikrishnan Dhanasekaran. Immunomodulatory actions of a Polynesian herb Noni (Morinda citrifolia) and its clinical applications. Complementary Therapies in Medicine 2019; 47: 102206 doi: 10.1016/j.ctim.2019.102206
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23 |
Débora de Oliveira Fernandes, Fernanda Gracia César, Bruno Pereira Melo, Jéssica da Silva Faria Brandão, Kelvin Jaques dos Santos, Marcelo Teixeira de Andrade, Marisa Cristina da Fonseca Casteluber, Moisés Vieira de Carvalho, Luiz Alexandre Medrado de Barcellos, Danusa Dias Soares, Juliana Bohnen Guimarães. Chronic supplementation of noni in diabetic type 1-STZ rats: effects on glycemic levels, kidney toxicity and exercise performance. Diabetology & Metabolic Syndrome 2023; 15(1) doi: 10.1186/s13098-023-01171-1
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24 |
Hemahwathy Chanthira Kumar, Xin Yi Lim, Farah Huda Mohkiar, Shazlan Noor Suhaimi, Nurmaziah Mohammad Shafie, Terence Yew Chin Tan. Efficacy and Safety of Morinda citrifolia L. (Noni) as a Potential Anticancer Agent. Integrative Cancer Therapies 2022; 21 doi: 10.1177/15347354221132848
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25 |
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26 |
Christian Frenzel, Rolf Teschke. Herbal Hepatotoxicity: Clinical Characteristics and Listing Compilation. International Journal of Molecular Sciences 2016; 17(5): 588 doi: 10.3390/ijms17050588
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Karl-Heinz Engel. Biofunktionalität der Lebensmittelinhaltsstoffe. Springer-Lehrbuch 2013; : 289 doi: 10.1007/978-3-642-29374-0_22
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Chit Shing Jackson Woo, Hani El-Nezami. Toxicology of Herbal Products. 2017; : 271 doi: 10.1007/978-3-319-43806-1_12
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Zoran Kovacevic, Goran Davidovic, Jelena Vuckovic-Filipovic, Mirjana A. Janicijevic-Petrovic, Katarina Janicijevic, Andrijana Popovic. A Toxic Hepatitis Caused the Kombucha Tea – Case Report. Open Access Macedonian Journal of Medical Sciences 2014; 2(1): 128 doi: 10.3889/oamjms.2014.023
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30 |
Tsuchida Akiyasu, Bishnuhari Paudyal, Pramila Paudyal, Matsumoto Kumiko, Ueki Kazue, Naruse Takuji, Kuroiwa Takashi, Nojima Yoshihisa, Komai Minoru. A Case Report of Acute Renal Failure Associated With Bee Pollen Contained in Nutritional Supplements. Therapeutic Apheresis and Dialysis 2010; 14(1): 93 doi: 10.1111/j.1744-9987.2009.00707.x
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C. Bunchorntavakul, K. R. Reddy. Review article: herbal and dietary supplement hepatotoxicity. Alimentary Pharmacology & Therapeutics 2013; 37(1): 3 doi: 10.1111/apt.12109
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32 |
William P. Clafshenkel, Tracy L. King, Mary P. Kotlarczyk, J. Mark Cline, Warren G. Foster, Vicki L. Davis, Paula A. Witt-Enderby. Morinda citrifolia(Noni) Juice Augments Mammary Gland Differentiation and Reduces Mammary Tumor Growth in Mice Expressing the Unactivated c-erbB2 Transgene. Evidence-Based Complementary and Alternative Medicine 2012; 2012: 1 doi: 10.1155/2012/487423
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33 |
Elizabeth Zheng, Víctor Navarro. Daño hepático debido al uso de suplementos nutricionales y de herbolario: revisión de componentes individuales. Clinical Liver Disease 2016; 8(S1): S30 doi: 10.1002/cld.597
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34 |
Peter Krisper, Rudolf E Stauber. Technology Insight: artificial extracorporeal liver support—how does Prometheus® compare with MARS®?. Nature Clinical Practice Nephrology 2007; 3(5): 267 doi: 10.1038/ncpneph0466
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35 |
Elizabeth Zheng, Victor Navarro. Liver injury due to herbal and dietary supplements: A review of individual ingredients. Clinical Liver Disease 2016; 7(4): 80 doi: 10.1002/cld.541
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36 |
Xiaoze Liu, Xue Lin, Xiaoping Hu, Congfa Li, Lu Wang, Tao Fei. Noni (Morinda citrifolia) fruit and by-products: A comprehensive review of its chemical compositions, health-promoting effects, safety assessment and industrial applications. Trends in Food Science & Technology 2024; 153: 104690 doi: 10.1016/j.tifs.2024.104690
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37 |
Thomas E. Marler, Jian Yang. Risk of Aluminum Exposure from Noni (Morinda citrifolia L.) Leaf Products1. Economic Botany 2013; 67(3): 203 doi: 10.1007/s12231-013-9236-5
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38 |
A. M. Mahfoudh, Norhayati Ismail, Sabariah Ismail, A. H. Hussin. In vitro ex vivoassessment ofMorinda citrifoliaon drug metabolizing enzymes in spontaneously hypertensive rats. Pharmaceutical Biology 2009; 47(12): 1108 doi: 10.3109/13880200903008658
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39 |
Elizabeth A. Hausner, Robert H. Poppenga. Small Animal Toxicology. 2013; : 335 doi: 10.1016/B978-1-4557-0717-1.00026-0
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40 |
Shivakumar Chitturi, Geoffrey C Farrell. Hepatotoxic slimming aids and other herbal hepatotoxins. Journal of Gastroenterology and Hepatology 2008; 23(3): 366 doi: 10.1111/j.1440-1746.2008.05310.x
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Dyély C.O. Campos, Andrea S. Costa, Amanda D.R. Lima, Fredy D.A. Silva, Marina D.P. Lobo, Ana Cristina O. Monteiro-Moreira, Renato A. Moreira, Luzia K.A.M. Leal, Diogo Miron, Ilka M. Vasconcelos, Hermógenes D. Oliveira. First isolation and antinociceptive activity of a lipid transfer protein from noni ( Morinda citrifolia ) seeds. International Journal of Biological Macromolecules 2016; 86: 71 doi: 10.1016/j.ijbiomac.2016.01.029
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42 |
Doris B. Strader, Victor J. Navarro, Leonard B. Seeff. Zakim and Boyer's Hepatology. 2012; : 462 doi: 10.1016/B978-1-4377-0881-3.00026-7
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43 |
Afa K. Palu, Anne Hirazumi Kim, Brett J. West, Shixin Deng, Jarakae Jensen, Leland White. The effects of Morinda citrifolia L. (noni) on the immune system: Its molecular mechanisms of action. Journal of Ethnopharmacology 2008; 115(3): 502 doi: 10.1016/j.jep.2007.10.023
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44 |
Eun Soo Kim, Chung Hyun Tae, Sung-Ae Jung, Dong Il Park, Jong Pil Im, Chang Soo Eun, Hyuk Yoon, Byung Ik Jang, Haruhiko Ogata, Kayoko Fukuhara, Fumihito Hirai, Kazuo Ohtsuka, Jing Liu, Qian Cao. Perspectives of East Asian patients and physicians on complementary and alternative medicine use for inflammatory bowel disease: results of a cross-sectional, multinational study. Intestinal Research 2022; 20(2): 192 doi: 10.5217/ir.2020.00150
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Fernando Almeida-Souza, Flávia de Oliveira Cardoso, Bruno Vinicius da Conceição Souza, Tânia Zaverucha do Valle, Joicy Cortez de Sá, Iara dos Santos da Silva Oliveira, Celeste da Silva Freitas de Souza, Carla Junqueira Moragas Tellis, Maria do Socorro dos Santos Chagas, Maria Dutra Behrens, Ana Lúcia Abreu-Silva, Kátia da Silva Calabrese, Peter C. Melby. Morinda citrifolia Linn. Reduces Parasite Load and Modulates Cytokines and Extracellular Matrix Proteins in C57BL/6 Mice Infected with Leishmania (Leishmania) amazonensis. PLOS Neglected Tropical Diseases 2016; 10(8): e0004900 doi: 10.1371/journal.pntd.0004900
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Anna Mrzljak, Iva Kosuta, Anita Skrtic, Tajana Filipec Kanizaj, Radovan Vrhovac. Drug-Induced Liver Injury Associated with Noni (Morinda citrifolia) Juice and Phenobarbital. Case Reports in Gastroenterology 2013; 7(1): 19 doi: 10.1159/000343651
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Keith Martin, Lacey Burrell, Jennifer Bopp. Tart cherry juice consumed daily for 4 weeks does not impair or exacerbate biomarkers of metabolic function in at‑risk overweight and obese subjects: A randomized, crossover pilot study. International Journal of Functional Nutrition 2020; 2(1) doi: 10.3892/ijfn.2020.12
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Johannes Westendorf, Katharina Effenberger, Hassan Iznaguen, Simla Basar. Toxicological and Analytical Investigations of Noni (Morinda citrifolia) Fruit Juice. Journal of Agricultural and Food Chemistry 2007; 55(2): 529 doi: 10.1021/jf062130i
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49 |
A. Douglas Kinghorn, Hee-byung Chai, Chung Ki Sung, William J. Keller. The classical drug discovery approach to defining bioactive constituents of botanicals. Fitoterapia 2011; 82(1): 71 doi: 10.1016/j.fitote.2010.08.015
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50 |
Esther Jiménez-Encarnación, Grissel Ríos, Angel Muñoz-Mirabal, Luis M Vilá. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Reports 2012; : bcr2012006907 doi: 10.1136/bcr-2012-006907
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51 |
Gabriela Mazzanti, Antonella Di Sotto, Annabella Vitalone. Hepatotoxicity of green tea: an update. Archives of Toxicology 2015; 89(8): 1175 doi: 10.1007/s00204-015-1521-x
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52 |
Herbal Does Not At All Mean Innocuous: The Sixth Case of Hepatotoxicity Associated With Morinda Citrifolia (Noni). The American Journal of Gastroenterology 2008; 103(9): 2406 doi: 10.1111/j.1572-0241.2008.02010_8.x
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Rolf Teschke, Albrecht Wolff, Christian Frenzel, Johannes Schulze, Axel Eickhoff. Herbal hepatotoxicity: a tabular compilation of reported cases. Liver International 2012; 32(10): 1543 doi: 10.1111/j.1478-3231.2012.02864.x
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Jasmina Dimitrova-Shumkovska, Leo Veenman, Trpe Ristoski, Svetlana Leschiner, Moshe Gavish. Chronic high fat, high cholesterol supplementation decreases 18kDa Translocator Protein binding capacity in association with increased oxidative stress in rat liver and aorta. Food and Chemical Toxicology 2010; 48(3): 910 doi: 10.1016/j.fct.2009.12.032
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Ui Joung Youn, Eun-Jung Park, Tamara P. Kondratyuk, Mayuramas Sang-Ngern, Marisa M. Wall, Yanzhang Wei, John M. Pezzuto, Leng Chee Chang. Anti-inflammatory and Quinone Reductase Inducing Compounds from Fermented Noni (Morinda citrifolia) Juice Exudates. Journal of Natural Products 2016; 79(6): 1508 doi: 10.1021/acs.jnatprod.5b00970
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Alison D. Pawlus, Bao-Ning Su, William J. Keller, A. Douglas Kinghorn. An Anthraquinone with Potent Quinone Reductase-Inducing Activity and Other Constituents of the Fruits of Morinda citrifolia (Noni). Journal of Natural Products 2005; 68(12): 1720 doi: 10.1021/np050383k
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Annelie Lindberg, Britt Ebbeskog, Per Karlen, Lena Oxelmark. Inflammatory bowel disease professionals’ attitudes to and experiences of complementary and alternative medicine. BMC Complementary and Alternative Medicine 2013; 13(1) doi: 10.1186/1472-6882-13-349
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Annelie Lindberg, Bjöörn Fossum, Per Karlen, Lena Oxelmark. Experiences of complementary and alternative medicine in patients with inflammatory bowel disease – a qualitative study. BMC Complementary and Alternative Medicine 2014; 14(1) doi: 10.1186/1472-6882-14-407
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B.J. West, C.J. Jensen, J. Westendorf, L.D. White. A Safety Review of Noni Fruit Juice. Journal of Food Science 2006; 71(8) doi: 10.1111/j.1750-3841.2006.00164.x
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Jing Dai, Ruyi Sha, Zhenzhen Wang, Yanli Cui, Sheng Fang, Jianwei Mao. Edible plant Jiaosu: manufacturing, bioactive compounds, potential health benefits, and safety aspects. Journal of the Science of Food and Agriculture 2020; 100(15): 5313 doi: 10.1002/jsfa.10518
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Ryanghyok IM, Hiroshi MANO, Sachie NAKATANI, Jun SHIMIZU, Masahiro WADA. Safety Evaluation of the Aqueous Extract Kothala Himbutu (Salacia reticulata) Stem in the Hepatic Gene Expression Profile of Normal Mice Using DNA Microarrays. Bioscience, Biotechnology, and Biochemistry 2008; 72(12): 3075 doi: 10.1271/bbb.70745
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Jason Phua, Kang Hoe Lee. Liver support devices. Current Opinion in Critical Care 2008; 14(2): 208 doi: 10.1097/MCC.0b013e3282f70057
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Bharat Singh, Ram A. Sharma. Indian Morinda species: A review. Phytotherapy Research 2020; 34(5): 924 doi: 10.1002/ptr.6579
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Nelson Fernando Quallio Marques, Ana Paula Bombonatto Mariano Marques, Ana Lívia Iwano, Munisa Golin, Rosangela Ribeiro De-Carvalho, Francisco José Roma Paumgartten, Paulo Roberto Dalsenter. Delayed ossification in Wistar rats induced by Morinda citrifolia L. exposure during pregnancy. Journal of Ethnopharmacology 2010; 128(1): 85 doi: 10.1016/j.jep.2009.12.029
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Amy C. Brown. Anticancer Activity of Morinda citrifolia (Noni) Fruit: A Review. Phytotherapy Research 2012; 26(10): 1427 doi: 10.1002/ptr.4595
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Thaís Leal-Silva, Maysa Rocha Souza, Larissa Lopes Cruz, Rafaianne Queiroz Moraes-Souza, Verônyca Gonçalves Paula, Thaigra Sousa Soares, Vanessa Dela Justina, Fernanda Regina Giachini, Débora Cristina Damasceno, Madileine Francely Américo, Gustavo Tadeu Volpato. Toxicological effects of the Morinda citrifolia L. fruit extract on maternal reproduction and fetal development in rats. Drug and Chemical Toxicology 2023; 46(3): 609 doi: 10.1080/01480545.2022.2070197
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Jacques Raymond Bernuau, François Durand. Herbal medicines in acute viral hepatitis: a ticket for more trouble. European Journal of Gastroenterology & Hepatology 2008; 20(3): 161 doi: 10.1097/MEG.0b013e3282f2bbf7
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Aline Carla Inada, Gabriela Torres Silva, Laleska Pâmela Rodrigues da Silva, Flávio Macedo Alves, Wander Fernando de Oliveira Filiú, Marcel Arakaki Asato, Wilson Hino Kato Junior, Joaquim Corsino, Patrícia de Oliveira Figueiredo, Fernanda Rodrigues Garcez, Walmir Silva Garcez, Renée de Nazaré Oliveira da Silva, Rosangela Aparecida dos Santos-Eichler, Rita de Cássia Avellaneda Guimarães, Karine de Cássia Freitas, Priscila Aiko Hiane. Therapeutic Effects of Morinda citrifolia Linn. (Noni) Aqueous Fruit Extract on the Glucose and Lipid Metabolism in High-Fat/High-Fructose-Fed Swiss Mice. Nutrients 2020; 12(11): 3439 doi: 10.3390/nu12113439
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Cyriac Abby Philips, Rizwan Ahamed, Sasidharan Rajesh, Tom George, Meera Mohanan, Philip Augustine. Comprehensive review of hepatotoxicity associated with traditional Indian Ayurvedic herbs. World Journal of Hepatology 2020; 12(9): 574-595 doi: 10.4254/wjh.v12.i9.574
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Pratibha Nerurkar, Phoebe Hwang, Erik Saksa. Anti-Diabetic Potential of Noni: The Yin and the Yang. Molecules 2015; 20(10): 17684 doi: 10.3390/molecules201017684
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Dipita Bhakta-Guha, Thomas Efferth. Medicinal Plants - Recent Advances in Research and Development. 2016; : 469 doi: 10.1007/978-981-10-1085-9_20
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Kavalipurapu Venkata Teja, Sindhu Ramesh, Karthik Ganesh, Kaligotla Apoorva Vasundhara. Evaluation of Morinda Citrifolia Ethanolic Extract Versus Morinda Citrifolia Fresh Fruit Juice for Tissue Response and Systemic Toxicity in Animal Model. Indian Journal of Dental Research 2021; 32(4): 423 doi: 10.4103/ijdr.IJDR_436_19
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Sangeeta D. Sule, Michelle Petri. Nutrition and Rheumatic Disease. Nutrition and Health 2008; : 159 doi: 10.1007/978-1-59745-403-2_9
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A. Carrillo-López, E.M. Yahia. Postharvest Biology and Technology of Tropical and Subtropical Fruits. 2011; : 51 doi: 10.1533/9780857092618.51
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Lena Oxelmark, Annelie Lindberg, Robert Löfberg, Berit Sternby, Anders Eriksson, Sven Almer, Ragnar Befrits, Bjöörn Fossum, Per Karlén, Olle Broström, Curt Tysk. Use of complementary and alternative medicine in Swedish patients with inflammatory bowel disease: a controlled study. European Journal of Gastroenterology & Hepatology 2016; 28(11): 1320 doi: 10.1097/MEG.0000000000000710
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Elizabeth L Yu, Mamata Sivagnanam, Linda Ellis, Jeannie S Huang. Acute Hepatotoxicity After Ingestion of Morinda citrifolia (Noni Berry) Juice in a 14‐year‐old Boy. Journal of Pediatric Gastroenterology and Nutrition 2011; 52(2): 222 doi: 10.1097/MPG.0b013e3181eb69f0
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Victor J. Navarro, Leonard B. Seeff. Liver Injury Induced by Herbal Complementary and Alternative Medicine. Clinics in Liver Disease 2013; 17(4): 715 doi: 10.1016/j.cld.2013.07.006
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Rui Ramos, Joana Mascarenhas, Patrícia Duarte, Célia Vicente, Carlos Casteleiro. Conjugated Linoleic Acid-Induced Toxic Hepatitis: First Case Report. Digestive Diseases and Sciences 2009; 54(5): 1141 doi: 10.1007/s10620-008-0461-1
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Amy C. Brown, Noelani Apau-Ludlum. Complementary and Alternative Therapies and the Aging Population. 2009; : 299 doi: 10.1016/B978-0-12-374228-5.00014-7
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Kent Sheridan, Christopher Kreulen, Sunny Kim, Walter Mak, Kirk Lewis, Richard Marder. Accuracy of magnetic resonance imaging to diagnose superior labrum anterior–posterior tears. Knee Surgery, Sports Traumatology, Arthroscopy 2015; 23(9): 2645 doi: 10.1007/s00167-014-3109-z
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