For: | Chen Y, Sze J, He ML. HBV cccDNA in patients’ sera as an indicator for HBV reactivation and an early signal of liver damage. World J Gastroenterol 2004; 10(1): 82-85 [PMID: 14695774 DOI: 10.3748/wjg.v10.i1.82] |
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URL: | https://www.wjgnet.com/1007-9327/full/v10/i1/82.htm |
Number | Citing Articles |
1 |
力玲 张. Progress of Hepatitis B Virus Biomarkers and Detection Methods. Medical Diagnosis 2013; 3(04): 57 doi: 10.12677/MD.2013.34013
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2 |
Xiaoling Li, Jinghua Zhao, Quan Yuan, Ningshao Xia. Detection of HBV Covalently Closed Circular DNA. Viruses 2017; 9(6): 139 doi: 10.3390/v9060139
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3 |
Pei-Xue Jiang, Ri-Cheng Mao, Min-Hui Dong, Xue-Ping Yu, Qi Xun, Jin-Yu Wang, Li Jing, Deng Qiang, Ji-Ming Zhang. Exonuclease I and III improve the detection efficacy of hepatitis B virus covalently closed circular DNA. Hepatobiliary & Pancreatic Diseases International 2019; 18(5): 458 doi: 10.1016/j.hbpd.2018.11.003
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4 |
Ju Luan, Jing Yuan, Xiaohe Li, Shengnan Jin, Ling Yu, Mingfeng Liao, Hongmei Zhang, Cheng Xu, Qing He, Bin Wen, Xunhua Zhong, Xinchun Chen, Henry L Y Chan, Joseph J Y Sung, Boping Zhou, Chunming Ding. Multiplex Detection of 60 Hepatitis B Virus Variants by MALDI-TOF Mass Spectrometry. Clinical Chemistry 2009; 55(8): 1503 doi: 10.1373/clinchem.2009.124859
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5 |
Ravinder Singh, Gayatri Ramakrishna, Manoj Kumar Sharma, Rahul Kumar, Ekta Gupta, Archana Rastogi, Pranay Tanwar, Shiv Kumar Sarin, Nirupama Trehanpati. Droplet digital PCR technique is ultrasensitive for the quantification of covalently closed circular DNA in the blood of chronic HBV-infected patients. Clinics and Research in Hepatology and Gastroenterology 2025; 49(3): 102531 doi: 10.1016/j.clinre.2025.102531
|
6 |
Franck Amblard, Sebastien Boucle, Leda Bassit, Bryan Cox, Ozkan Sari, Sijia Tao, Zhe Chen, Tugba Ozturk, Kiran Verma, Olivia Russell, Virgile Rat, Hugues de Rocquigny, Oriane Fiquet, Maud Boussand, James Di Santo, Helene Strick-Marchand, Raymond F. Schinazi.
Novel Hepatitis B Virus Capsid Assembly Modulator Induces Potent Antiviral Responses
In Vitro
and in Humanized Mice
. Antimicrobial Agents and Chemotherapy 2020; 64(2) doi: 10.1128/AAC.01701-19
|
7 |
Guojun Shen, Xihua Fu, Bin Zhou, Junhua Yin, Chunxiu Zhong, Jinjun Chen, Jinlin Hou. Duck HBV Dna Copy Numbers in Isolated Hepatocyte Nuclei Vary Dramatically and Decline during Entecavir Therapy. Antiviral Therapy 2013; 18(8): 987 doi: 10.3851/IMP2653
|
8 |
Sheila F. Lumley, Chris Kent, Daisy Jennings, Haiting Chai, George Airey, Elizabeth Waddilove, Marion Delphin, Amy Trebes, Anna L. McNaughton, Khadija Said Mohammed, Sam A. J. Wilkinson, Yanxia Wu, George MacIntyre-Cockett, Beatrice Kimono, Kwizera Moses Mbonye, Kevin Ojambo, Tongai G. Maponga, Cedric C. S. Tan, Catherine de Lara, Jacqueline Martin, James Campbell, Marije Van Schalkwyk, Dominique Goedhals, Robert Newton, Eleanor Barnes, Nicholas J. Loman, Paolo Piazza, Joshua Quick, M. Azim Ansari, Philippa C. Matthews. Whole genome sequencing of hepatitis B virus using tiled amplicon (HEPTILE) and probe based enrichment on Illumina and Nanopore platforms. Scientific Reports 2025; 15(1) doi: 10.1038/s41598-025-87721-1
|
9 |
Man-Fung Yuen, Danny Ka-Ho Wong, Simon Siu-Man Sum, He-Jun Yuan, John Chi-Hang Yuen, Annie On-On Chan, Benjamin Chun-Yu Wong, Ching-Lung Lai. Effect of Lamivudine Therapy on the Serum Covalently Closed-Circular (ccc) DNA of Chronic Hepatitis B Infection. The American Journal of Gastroenterology 2005; 100(5): 1099 doi: 10.1111/j.1572-0241.2005.41530.x
|
10 |
Yong-Hong Sun, Xiao-Yan Lei, Yi-Pa Sai, Jun-Hui Chen, Yuan-Chun Sun, Xia Gao. Relationship between genotypes and clinical manifestation, pathology, and cccDNA in Chinese children with hepatitis B virus-associated glomerulonephritis. World Journal of Pediatrics 2016; 12(3): 347 doi: 10.1007/s12519-016-0015-0
|
11 |
Andreas Laras, Margarita Papatheodoridi, Eleni Panopoulou, George V. Papatheodoridis, Stephanos J. Hadziyannis, Emilia Hadziyannis. Serum hepatitis B virus RNA detectability, composition and clinical significance in patients with ab initio hepatitis B e antigen negative chronic hepatitis B. Virology Journal 2022; 19(1) doi: 10.1186/s12985-022-01749-7
|
12 |
D S Kostyushev, A P Zueva, S A Brezgin, A D Lipatnikov, V N Simirskii, D Glebe, E V Volchkova, G A Shipulin, V P Chulanov. Overexpression of DNA-methyltransferases in persistency of cccDNA pool in chronic hepatitis B. Terapevticheskii arkhiv 2017; 89(11): 21 doi: 10.17116/terarkh2017891121-26
|
13 |
Zhi Yi Goh, Ee Chee Ren, Hui Ling Ko. Intracellular interferon signalling pathways as potential regulators of covalently closed circular DNA in the treatment of chronic hepatitis B. World Journal of Gastroenterology 2021; 27(14): 1369-1391 doi: 10.3748/wjg.v27.i14.1369
|
14 |
R.B. Takkenberg, H.L. Zaaijer, R. Molenkamp, S. Menting, V. Terpstra, C.J. Weegink, M.G.W. Dijkgraaf, P.L.M. Jansen, H.W. Reesink, M.G.H.M. Beld. Validation of a sensitive and specific real‐time PCR for detection and quantitation of hepatitis B virus covalently closed circular DNA in plasma of chronic hepatitis B patients. Journal of Medical Virology 2009; 81(6): 988 doi: 10.1002/jmv.21477
|
15 |
Ananya Pal, Neelakshi Sarkar, Debraj Saha, Subhashish K Guha, Bibhuti Saha, Sekhar Chakrabarti, Runu Chakravarty. High Incidence of Lamivudine-Resistance-Associated Vaccine-Escape HBV Mutants among HIV-Coinfected Patients on Prolonged Antiretroviral Therapy. Antiviral Therapy 2015; 20(5): 545 doi: 10.3851/IMP2942
|
16 |
Edward M. Kennedy, Leda C. Bassit, Henrik Mueller, Anand V.R. Kornepati, Hal P. Bogerd, Ting Nie, Payel Chatterjee, Hassan Javanbakht, Raymond F. Schinazi, Bryan R. Cullen. Suppression of hepatitis B virus DNA accumulation in chronically infected cells using a bacterial CRISPR/Cas RNA-guided DNA endonuclease. Virology 2015; 476: 196 doi: 10.1016/j.virol.2014.12.001
|
17 |
Madina Karimova, Niklas Beschorner, Werner Dammermann, Jan Chemnitz, Daniela Indenbirken, Jan-Hendrik Bockmann, Adam Grundhoff, Stefan Lüth, Frank Buchholz, Julian Schulze zur Wiesch, Joachim Hauber. CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X. Scientific Reports 2015; 5(1) doi: 10.1038/srep13734
|
18 |
Bhupesh Singla, Anuradha Chakraborti, Bal Krishan Sharma, Shweta Kapil, Yogesh K. Chawla, Sunil K. Arora, Ashim Das, Radha K. Dhiman, Ajay Duseja. Levels of hepatitis B virus replicative intermediate in serum samples of chronic hepatitis B patients. Molecular Biology Reports 2014; 41(7): 4689 doi: 10.1007/s11033-014-3339-7
|
19 |
Forough Golsaz Shirazi, Hamed Mohammadi, Mohammad Mehdi Amiri, Katrin Singethan, Yuchen Xia, Ali Ahmad Bayat, Motahareh Bahadori, Hodjatallah Rabbani, Mahmood Jeddi‐Tehrani, Ulrike Protzer, Fazel Shokri. Monoclonal antibodies to various epitopes of hepatitis B surface antigen inhibit hepatitis B virus infection. Journal of Gastroenterology and Hepatology 2014; 29(5): 1083 doi: 10.1111/jgh.12483
|
20 |
Verena Schildgen, Soumaya Khalfaoui, Oliver Schildgen. Human bocavirus. Reviews in Medical Microbiology 2014; 25(4): 113 doi: 10.1097/MRM.0000000000000010
|
21 |
A.A. Mazet-Wagner, M.C. Baclet, V. Loustaud-Ratti, F. Denis, S. Alain. Real-time PCR quantitation of hepatitis B virus total DNA and covalently closed circular DNA in peripheral blood mononuclear cells from hepatitis B virus-infected patients. Journal of Virological Methods 2006; 138(1-2): 70 doi: 10.1016/j.jviromet.2006.07.019
|
22 |
Anastasiya Kostyusheva, Dmitry Kostyushev, Sergey Brezgin, Elena Volchkova, Vladimir Chulanov. Clinical Implications of Hepatitis B Virus RNA and Covalently Closed Circular DNA in Monitoring Patients with Chronic Hepatitis B Today with a Gaze into the Future: The Field Is Unprepared for a Sterilizing Cure. Genes 2018; 9(10): 483 doi: 10.3390/genes9100483
|
23 |
Ee Chee Ren, Nicole Ziyi Zhuo, Zhi Yi Goh, Isabelle Bonne, Benoît Malleret, Hui Ling Ko. cccDNA-Targeted Drug Screen Reveals a Class of Antihistamines as Suppressors of HBV Genome Levels. Biomolecules 2023; 13(10): 1438 doi: 10.3390/biom13101438
|
24 |
R. Bart Takkenberg, Hans L. Zaaijer, Sandra Menting, Christine J. Weegink, Valeska Terpstra, Marion Cornelissen, Marcel G.W. Dijkgraaf, Peter L.M. Jansen, Hendrik W. Reesink, Marcel G.H.M. Beld. Detection of hepatitis B virus covalently closed circular DNA in paraffin-embedded and cryo-preserved liver biopsies of chronic hepatitis B patients. European Journal of Gastroenterology & Hepatology 2010; 22(8): 952 doi: 10.1097/MEG.0b013e3283376a63
|
25 |
Xiaohong Cao, Minghui Zhou, Songxue Wang, Chunling Wang, Lihua Hou, Yiqing Luo, Linye Chen. Inhibition on hepatitis B virus in vitro of lectin from Musca domestica pupa via the activation of NF-κB. Virus Research 2012; 170(1-2): 53 doi: 10.1016/j.virusres.2012.08.012
|
26 |
Hung-Wen Tsai, Yih-Jyh Lin, Han-Chieh Wu, Ting-Tsung Chang, I-Chin Wu, Pin-Nan Cheng, Chia-Jui Yen, Shih-Huang Chan, Wenya Huang, Ih-Jen Su. Resistance of ground glass hepatocytes to oral antivirals in chronic hepatitis B patients and implication for the development of hepatocellular carcinoma. Oncotarget 2016; 7(19): 27724 doi: 10.18632/oncotarget.8388
|
27 |
Shuai Zhen, Rong Qiang, Jiaojiao Lu, Xiaoqian Tuo, Xiling Yang, Xu Li. Enhanced antiviral benefit of combination therapy with anti-HBV and anti-PD1 gRNA/cas9 produces a synergistic antiviral effect in HBV infection. Molecular Immunology 2021; 130: 7 doi: 10.1016/j.molimm.2020.12.004
|
28 |
Wei Feng Low, Yun Fong Ngeow, Jack Bee Chook, Kok Keng Tee, Seng-Kai Ong, Suat Cheng Peh, Jan Jin Bong, Rosmawati Mohamed. Hepatitis B virus DNA methylation and its potential role in chronic hepatitis B. Expert Reviews in Molecular Medicine 2023; 25 doi: 10.1017/erm.2022.38
|
29 |
Yanwei Zhong, Jiaqi Han, Zhengsheng Zou, Shuhong Liu, Bo Tang, Xiaoqiang Ren, Xiaodong Li, Yulai Zhao, Yan Liu, Dongqing Zhou, Weijie Li, Jingmin Zhao, Dongping Xu. Quantitation of HBV covalently closed circular DNA in micro formalin fixed paraffin-embedded liver tissue using rolling circle amplification in combination with real-time PCR. Clinica Chimica Acta 2011; 412(21-22): 1905 doi: 10.1016/j.cca.2011.06.031
|
30 |
Heba A. Osman, Helal F. Hetta, Ahmad M. El-Adly, Ahmad K. Meshaal, Mohamed A. Mekky. Detectability of Hepatitis B Virus in Peripheral Blood Mononuclear Cells Among Naive Chronic Hepatitis B Patients With Negative Viremia. Infectious Diseases in Clinical Practice 2022; 30(5) doi: 10.1097/IPC.0000000000001153
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31 |
|
32 |
Naveen Kumar, Shalini Sharma, Ram Kumar, Bhupendra N. Tripathi, Sanjay Barua, Hinh Ly, Barry T. Rouse. Host-Directed Antiviral Therapy. Clinical Microbiology Reviews 2020; 33(3) doi: 10.1128/CMR.00168-19
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33 |
Yingshan Chen, Yongxuan Yao, Kaitao Zhao, Canyu Liu, Yifei Yuan, Hao Sun, Dan Huang, Yi Zheng, Yuan Zhou, Jizheng Chen, Yun Wang, Chunchen Wu, Bixiang Zhang, Yujuan Guan, Feng Li, Rongjuan Pei, Xinwen Chen, J.-H. James Ou. DNA Repair Factor Poly(ADP-Ribose) Polymerase 1 Is a Proviral Factor in Hepatitis B Virus Covalently Closed Circular DNA Formation. Journal of Virology 2022; 96(13) doi: 10.1128/jvi.00585-22
|
34 |
Ming Shi, Wan-Li Sun, Yan-Yan Hua, Bo Han, Long Shi, James Fung. Effects of Entecavir on Hepatitis B Virus Covalently Closed Circular DNA in Hepatitis B e Antigen-Positive Patients with Hepatitis B. PLOS ONE 2015; 10(2): e0117741 doi: 10.1371/journal.pone.0117741
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35 |
Verena Schildgen, Monika Malecki, Ramona-Liza Tillmann, Michael Brockmann, Oliver Schildgen, Amit Kapoor. The Human Bocavirus Is Associated with Some Lung and Colorectal Cancers and Persists in Solid Tumors. PLoS ONE 2013; 8(6): e68020 doi: 10.1371/journal.pone.0068020
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36 |
Z. Liu, L. Jiang, G. Liang, E. Song, W. Jiang, Y. Zheng, C. Gong. Hepatitis B virus reactivation in breast cancer patients undergoing chemotherapy: A review and meta‐analysis of prophylaxis management. Journal of Viral Hepatitis 2017; 24(7): 561 doi: 10.1111/jvh.12672
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37 |
Xiao-Hong Shi, Bo Wang, Shu-Ying Feng, Zhen Guo, Jian Guo, Xue-Fei Wang, Shu-Zhen Li, Yong-Liang Feng, Su-Ping Wang. Influential Factors of Hepatitis B Virus cccDNA in Peripheral Blood Mononuclear Cells Among HBsAg-Positive Pregnant Females Neonates. Hepatitis Monthly 2018; (In Press) doi: 10.5812/hepatmon.55064
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38 |
Nora Martel, Selma A. Gomes, Isabelle Chemin, Christian Trépo, Alan Kay. Improved rolling circle amplification (RCA) of hepatitis B virus (HBV) relaxed-circular serum DNA (RC-DNA). Journal of Virological Methods 2013; 193(2): 653 doi: 10.1016/j.jviromet.2013.07.045
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39 |
Yongcan Guo, Shangchun Sheng, Bin Nie, Zhiguang Tu. Development of Magnetic Capture Hybridization and Quantitative Polymerase Chain Reaction for Hepatitis B Virus Covalently Closed Circular DNA. Hepatitis Monthly 2015; 15(1) doi: 10.5812/hepatmon.23729
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40 |
Ying-Tang Gao, Tao Han, Ying Li, Bin Yang, Yi-Jun Wang, Feng-mei Wang, Xiang Jing, Zhi Du. Enhanced specificity of real-time PCR for measurement of hepatitis B virus cccDNA using restriction endonuclease and plasmid-safe ATP-dependent DNase and selective primers. Journal of Virological Methods 2010; 169(1): 181 doi: 10.1016/j.jviromet.2010.07.031
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41 |
Zahra Tajik, Hossein Keyvani, Farah Bokharaei-Salim, Mohammad Reza Zolfaghari, Shahin Fakhim, Maryam Keshvari, Seyed Moayed Alavian. Detection of Hepatitis B Virus Covalently Closed Circular DNA in the Plasma of Iranian HBeAg-Negative Patients With Chronic Hepatitis B. Hepatitis Monthly 2015; 15(9) doi: 10.5812/hepatmon.30790
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42 |
M. M. YU, X. J GU, Y. XIA, G. J. WANG, N. Y. KAN, H. X. JIANG, K. H. WU, Y. JI, L. L. JU. Relationship between HBV cccDNA expression in the human ovary and vertical transmission of HBV. Epidemiology and Infection 2012; 140(8): 1454 doi: 10.1017/S0950268811002068
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