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For: Mottino AD, Catania VA. Hepatic drug transporters and nuclear receptors: Regulation by therapeutic agents. World J Gastroenterol 2008; 14(46): 7068-7074 [PMID: 19084913 DOI: 10.3748/wjg.14.7068]
URL: https://www.wjgnet.com/1007-9327/full/v14/i46/7068.htm
Number Citing Articles
1
Obeid M. Malekshah, Hermann lage, Ahmad Reza Bahrami, Jalil Tavakol Afshari, Javad Behravan. PXR and NF-κB correlate with the inducing effects of IL-1β and TNF-α on ABCG2 expression in breast cancer cell linesEuropean Journal of Pharmaceutical Sciences 2012; 47(2): 474 doi: 10.1016/j.ejps.2012.06.011
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J.A. Bjork, J.L. Butenhoff, K.B. Wallace. Multiplicity of nuclear receptor activation by PFOA and PFOS in primary human and rodent hepatocytesToxicology 2011; 288(1-3): 8 doi: 10.1016/j.tox.2011.06.012
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Jing-Jing Yuan, Xiao-Jing Ma, Zhi-Song Li, Yan-Zi Chang, Wei Zhang, Quan-Cheng Kan, Jun-Kai Hou, Li-Rong Zhang. Effect of Pregnane X Receptor*1B genetic polymorphisms on postoperative analgesia with fentanyl in Chinese patients undergoing gynecological surgeryBMC Medical Genetics 2016; 17(1) doi: 10.1186/s12881-016-0348-5
4
Kenneth W. Dunn, Jennifer C. Ryan. Using quantitative intravital multiphoton microscopy to dissect hepatic transport in ratsMethods 2017; 128: 40 doi: 10.1016/j.ymeth.2017.04.015
5
Ronald PJ Oude Elferink, Ulrich Beuers. Targeting the ABCB4 gene to control cholesterol homeostasisExpert Opinion on Therapeutic Targets 2011; 15(10): 1173 doi: 10.1517/14728222.2011.607163
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Man Li, Wei Wang, Carol J. Soroka, Albert Mennone, Kathy Harry, Edward J. Weinman, James L. Boyer. NHERF-1 Binds to Mrp2 and Regulates Hepatic Mrp2 Expression and FunctionJournal of Biological Chemistry 2010; 285(25): 19299 doi: 10.1074/jbc.M109.096081
7
Mariline Gameiro, Renata Silva, Carolina Rocha-Pereira, Helena Carmo, Félix Carvalho, Maria Bastos, Fernando Remião. Cellular Models and In Vitro Assays for the Screening of modulators of P-gp, MRP1 and BCRPMolecules 2017; 22(4): 600 doi: 10.3390/molecules22040600
8
Congrong Niu, Bill Smith, Yurong Lai. Transporter Gene Regulation in Sandwich Cultured Human Hepatocytes Through the Activation of Constitutive Androstane Receptor (CAR) or Aryl Hydrocarbon Receptor (AhR)Frontiers in Pharmacology 2021; 11 doi: 10.3389/fphar.2020.620197
9
Kentaro Yano, Suzune Mita, Kaori Morimoto, Tamami haraguchi, Hiroshi arakawa, Miyako Yoshida, Fumiyoshi Yamashita, Takahiro Uchida, Takuo Ogihara. Multiple Linear Regression Analysis Indicates Association of P-Glycoprotein Substrate or Inhibitor Character with Bitterness Intensity Measured with a SensorJournal of Pharmaceutical Sciences 2015; 104(9): 2789 doi: 10.1002/jps.24232
10
Obeid M. Malekshah, Ahmad Reza Bahrami, Jalil Tavakol Afshari, Fatemeh Mosaffa, Javad Behravan. Correlation BetweenPXRandABCG2Patterns of mRNA Expression in a MCF7 Breast Carcinoma Cell Derivative upon Induction by Proinflammatory CytokinesDNA and Cell Biology 2011; 30(1): 25 doi: 10.1089/dna.2010.1074
11
Akhil Sharma, Ashi Mannan, Shareen Singh, Thakur Gurjeet Singh. A second act for spironolactone: cognitive benefits in renal dysfunction – a critical reviewMetabolic Brain Disease 2025; 40(5) doi: 10.1007/s11011-025-01623-9
12
Eric A. Benson, Michael T. Eadon, Zeruesenay Desta, Yunlong Liu, Hai Lin, Kimberly S. Burgess, Matthew W. Segar, Andrea Gaedigk, Todd C. Skaar. Rifampin Regulation of Drug Transporters Gene Expression and the Association of MicroRNAs in Human HepatocytesFrontiers in Pharmacology 2016; 7 doi: 10.3389/fphar.2016.00111
13
David E. Amacher. The regulation of human hepatic drug transporter expression by activation of xenobiotic-sensing nuclear receptorsExpert Opinion on Drug Metabolism & Toxicology 2016; 12(12): 1463 doi: 10.1080/17425255.2016.1223626
14
Kentaro Yano, Yumiko Iwase, Takuo Ogihara, Takashi Kuwabara. 【Continuous exposure to therapeutic drugs doxorubicin and vincristine reduces drug efficacy through transcriptional and post-transcriptional regulation of P-glycoprotein in follicular lymphoma】Drug Metabolism and Pharmacokinetics 2025; : 101495 doi: 10.1016/j.dmpk.2025.101495
15
Katrin Zeilinger, Thomas Schreiter, Malin Darnell, Therese Söderdahl, Marc Lübberstedt, Birgitta Dillner, Daniel Knobeloch, Andreas K. Nüssler, Jörg C. Gerlach, Tommy B. Andersson. Scaling Down of a Clinical Three-Dimensional Perfusion Multicompartment Hollow Fiber Liver Bioreactor Developed for Extracorporeal Liver Support to an Analytical Scale Device Useful for Hepatic Pharmacological In Vitro StudiesTissue Engineering Part C: Methods 2011; 17(5): 549 doi: 10.1089/ten.tec.2010.0580
16
Silvina Villanueva, Wei Zhang, Felipe Zecchinati, Aldo Mottino, Mary Vore. ABC Transporters in Extrahepatic Tissues: Pharmacological Regulation in Heart and IntestineCurrent Medicinal Chemistry 2019; 26(7): 1155 doi: 10.2174/0929867325666180327092639
17
Béatrice Marquez, Geneviève Ameye, Coralie M. Vallet, Paul M. Tulkens, Hélène A. Poirel, Françoise Van Bambeke, Hendrik W. van Veen. Characterization of Abcc4 Gene Amplification in Stepwise-Selected Mouse J774 Macrophages Resistant to the Topoisomerase II Inhibitor CiprofloxacinPLoS ONE 2011; 6(12): e28368 doi: 10.1371/journal.pone.0028368
18
Rachida Bouamar, Dennis A Hesselink, Ron H N van Schaik, Willem Weimar, Iain A M MacPhee, Johan W de Fijter, Teun van Gelder. Polymorphisms in CYP3A5, CYP3A4, and ABCB1 are Not Associated With Cyclosporine Pharmacokinetics Nor With Cyclosporine Clinical End Points After Renal TransplantationTherapeutic Drug Monitoring 2011; 33(2): 178 doi: 10.1097/FTD.0b013e31820feb8e
19
Kazumasa Naruhashi, Yuko Kurahashi, Yukari Fujita, Eri Kawakita, Yuna Yamasaki, Kana Hattori, Asako Nishimura, Nobuhito Shibata. Comparison of the Expression and Function of ATP Binding Cassette Transporters in Caco-2 and T84 cells on Stimulation by Selected Endogenous Compounds and XenobioticsDrug Metabolism and Pharmacokinetics 2011; 26(2): 145 doi: 10.2133/dmpk.DMPK-10-RG-075
20
J.-F. Ghersi-Egea, K.S. Mönkkönen, C. Schmitt, J. Honnorat, M. Fèvre-Montange, N. Strazielle. Blood–brain interfaces and cerebral drug bioavailabilityRevue Neurologique 2009; 165(12): 1029 doi: 10.1016/j.neurol.2009.09.011
21
C. W. Rivero, N. Rosso, E. Gentile, M. Cuestas, C. Tiribelli, J. R. Oubiña, V. L. Mathet. Dissimilar expression of multidrug resistance mdr1 and bcrp by the replication of hepatitis C virus: role of the nonstructural 5A proteinJournal of Viral Hepatitis 2013; 20(4) doi: 10.1111/jvh.12028
22
Guo‑Rong He, Xiao‑Kun Lin, Yong‑Biao Wang, Cong‑De Chen. Dexmedetomidine impairs P‑glycoprotein‑mediated efflux function in L02 cells via the adenosine 5'‑monophosphate‑activated protein kinase/nuclear factor‑κB pathwayMolecular Medicine Reports 2018;  doi: 10.3892/mmr.2018.8549
23
J.B. Watkins, C.D. Klaassen. Comprehensive Toxicology2010; : 77 doi: 10.1016/B978-0-08-046884-6.00847-2
24
Lizi Zhao, Gisèle Pickering. Paracetamol metabolism and related genetic differencesDrug Metabolism Reviews 2011; 43(1): 41 doi: 10.3109/03602532.2010.527984
25
Paul Jennings, Michael Schwarz, Brigitte Landesmann, Silvia Maggioni, Marina Goumenou, David Bower, Martin O. Leonard, Jeffrey S. Wiseman. SEURAT-1 liver gold reference compounds: a mechanism-based reviewArchives of Toxicology 2014; 88(12): 2099 doi: 10.1007/s00204-014-1410-8
26
Bettina Gerner, Oliver Scherf-Clavel. Physiologically Based Pharmacokinetic Modelling of Cabozantinib to Simulate Enterohepatic Recirculation, Drug–Drug Interaction with Rifampin and Liver ImpairmentPharmaceutics 2021; 13(6): 778 doi: 10.3390/pharmaceutics13060778
27
Carolina I. Ghanem, Agostina Arias, Analia Novak, Griselda Delli Carpini, Silvina Villanueva, Alba G. Blazquez, Jose J.G. Marin, Aldo D. Mottino, Modesto C. Rubio. Acetaminophen-induced stimulation of MDR1 expression and activity in rat intestine and in LS 174T human intestinal cell lineBiochemical Pharmacology 2011; 81(2): 244 doi: 10.1016/j.bcp.2010.10.006
28
Malin C. Celander. Cocktail effects on biomarker responses in fishAquatic Toxicology 2011; 105(3-4): 72 doi: 10.1016/j.aquatox.2011.06.002
29
Sarah Shugarts, Leslie Z. Benet. The Role of Transporters in the Pharmacokinetics of Orally Administered DrugsPharmaceutical Research 2009; 26(9): 2039 doi: 10.1007/s11095-009-9924-0
30
Xieyi Zhang, Wangyang Liu, Kazue Edaki, Yuta Nakazawa, Hiroki Kamioka, Atsushi Fujita, Ryoichi Onozato, Misa Iijima, Shigeru Tsuchida, Takahiro Arai, Yukiyoshi Fujita, Kenta Mizoi, Takuo Ogihara, Mohd Adnan. Correlations of mRNA Levels among Efflux Transporters, Transcriptional Regulators, and Scaffold Proteins in Non-Small-Cell Lung CancerCanadian Journal of Infectious Diseases and Medical Microbiology 2021; 2021: 1 doi: 10.1155/2021/4005327
31
Renli Teng, Patrick Mitchell, Kathleen Butler. Effect of age and gender on pharmacokinetics and pharmacodynamics of a single ticagrelor dose in healthy individualsEuropean Journal of Clinical Pharmacology 2012; 68(8): 1175 doi: 10.1007/s00228-012-1227-4
32
Clifford M. Babbey, Jennifer C. Ryan, Erin M. Gill, Marwan S. Ghabril, Courtney R. Burch, April Paulman, Kenneth W. Dunn. Quantitative intravital microscopy of hepatic transportIntraVital 2012; 1(1): 44 doi: 10.4161/intv.21296
33
Bruno Stieger, Gerd A. Kullak-Ublick. Drug-Induced Liver Disease2013; : 123 doi: 10.1016/B978-0-12-387817-5.00007-8
34
Raúl Ortíz, Francisco Quiñonero, Beatriz García-Pinel, Marco Fuel, Cristina Mesas, Laura Cabeza, Consolación Melguizo, Jose Prados. Nanomedicine to Overcome Multidrug Resistance Mechanisms in Colon and Pancreatic Cancer: Recent ProgressCancers 2021; 13(9): 2058 doi: 10.3390/cancers13092058
35
Jianmei Sun, He Bao, Yajie Peng, Haimin Zhang, Ya Sun, Jiajun Qi, Hailong Zhang, Yang Gao. Improvement of intestinal transport, absorption and anti-diabetic efficacy of berberine by using Gelucire44/14: In vitro, in situ and in vivo studiesInternational Journal of Pharmaceutics 2018; 544(1): 46 doi: 10.1016/j.ijpharm.2018.04.014
36
Man Li, Carol J. Soroka, Kathy Harry, James L. Boyer. CFTR-associated ligand is a negative regulator of Mrp2 expressionAmerican Journal of Physiology-Cell Physiology 2017; 312(1): C40 doi: 10.1152/ajpcell.00100.2016
37
Bettina Ebert, Michael Kisiela, Petra Malátková, Yasser El-Hawari, Edmund Maser. Regulation of Human Carbonyl Reductase 3 (CBR3; SDR21C2) Expression by Nrf2 in Cultured Cancer CellsBiochemistry 2010; 49(39): 8499 doi: 10.1021/bi100814d
38
Kentaro Yano, Saori Shimizu, Takumi Tomono, Takuo Ogihara. Gastrointestinal Hormone Cholecystokinin Increases P-Glycoprotein Membrane Localization and Transport Activity in Caco-2 CellsJournal of Pharmaceutical Sciences 2017; 106(9): 2650 doi: 10.1016/j.xphs.2017.04.003
39
Charles Awortwe, Meike Kaehler, Bernd Rosenkranz, Ingolf Cascorbi, Henrike Bruckmueller. MicroRNA-655-3p regulates Echinacea purpurea mediated activation of ABCG2Xenobiotica 2018; 48(10): 1050 doi: 10.1080/00498254.2017.1390624
40
Jyrki J. Eloranta, Bruno Stieger, Gerd A. Kullak‐Ublick. Drug Transporters2014; : 127 doi: 10.1002/9781118705308.ch8
41
Radim Vrzal, Aneta Doricakova, Aneta Novotna, Petr Bachleda, Michal Bitman, Petr Pavek, Zdenek Dvorak. Valproic acid augments vitamin D receptor-mediated induction of CYP24 by vitamin D3: A possible cause of valproic acid-induced osteomalacia?Toxicology Letters 2011; 200(3): 146 doi: 10.1016/j.toxlet.2010.11.008
42
J.B. Watkins, C.D. Klaassen. Comprehensive Toxicology2018; : 99 doi: 10.1016/B978-0-12-801238-3.02122-X
43
Alba G. Blazquez, Oscar Briz, Ester Gonzalez-Sanchez, Maria J. Perez, Carolina I. Ghanem, Jose J.G. Marin. The effect of acetaminophen on the expression of BCRP in trophoblast cells impairs the placental barrier to bile acids during maternal cholestasisToxicology and Applied Pharmacology 2014; 277(1): 77 doi: 10.1016/j.taap.2014.02.019
44
Takuo Ogihara, Kenta Mizoi, Hiroki Kamioka, Kentaro Yano. Physiological Roles of ERM Proteins and Transcriptional Regulators in Supporting Membrane Expression of Efflux Transporters as Factors of Drug Resistance in CancerCancers 2020; 12(11): 3352 doi: 10.3390/cancers12113352
45
Congrong Niu, Yujin Wang, Xiaofeng Zhao, Sam Tep, Eisuke Murakami, Raju Subramanian, Bill Smith, Yurong Lai. Organic Anion-Transporting Polypeptide Genes Are Not Induced by the Pregnane X Receptor Activator Rifampin: Studies in Hepatocytes In Vitro and in Monkeys In VivoDrug Metabolism and Disposition 2019; 47(12): 1433 doi: 10.1124/dmd.119.088922
46
Zhaosha Li, J. Kar Kruijt, Ronald J. van der Sluis, Theo J. C. Van Berkel, Menno Hoekstra. Nuclear receptor atlas of female mouse liver parenchymal, endothelial, and Kupffer cellsPhysiological Genomics 2013; 45(7): 268 doi: 10.1152/physiolgenomics.00151.2012
47
Xieyi Zhang, Wangyang Liu, Kazue Edaki, Yuta Nakazawa, Saori Takahashi, Hiroki Sunakawa, Kenta Mizoi, Takuo Ogihara. Slug Mediates MRP2 Expression in Non-Small Cell Lung Cancer CellsBiomolecules 2022; 12(6): 806 doi: 10.3390/biom12060806
48
Bruno Stieger, Peter J Meier. Pharmacogenetics of Drug Transporters in the Enterohepatic CirculationPharmacogenomics 2011; 12(5): 611 doi: 10.2217/pgs.11.53
49
Nagendra Kumar Chaturvedi, Sanjay Kumar, Seema Negi, Rakesh K. Tyagi. Endocrine disruptors provoke differential modulatory responses on androgen receptor and pregnane and xenobiotic receptor: potential implications in metabolic disordersMolecular and Cellular Biochemistry 2010; 345(1-2): 291 doi: 10.1007/s11010-010-0583-6