Baishideng Publishing Group

Tang L, Wang YY, Lei HK, Wang CM, Teng Y, Xu QJ, Jiang QM, Chen B, Zeng XH, Guo BQ, Wang EW. Clinical characteristics and prognostic factors in patients with malignant melanoma: A Chinese prospective cohort study. World J Clin Oncol 2025; 16(6): 105813

"We are honored to have our manuscript published in the World Journal of Diabetes (WJD). Throughout the submission and publication ..." [Read more]

"We are honored to have our manuscript published in the World Journal of Diabetes (WJD). Throughout the submission and publication process, we found the journal to demonstrate high academic standards and professional editorial management. The journal has a clear and transparent peer-review system, and the editorial team maintained effective communication with us at every stage. The reviewers provided valuable and constructive feedback that significantly improved the quality of our manuscript. Additionally, the journal adheres to internationally recognized ethical standards, and the publication process was efficient and well-organized. As a journal indexed in reputable databases and focused specifically on the field of diabetes research, WJD provides an important platform for disseminating advances in both clinical and basic research. We appreciate the opportunity to contribute to this journal and look forward to further academic exchanges. " [Collapse]

He BB, Liu ZZ, Xu RY, Fan L, Guo R, Deng C, Xie YT, Zhou ZG, Li X. Glycated hemoglobin is not enough: The role of glycemia risk index for glycemic control assessment in type 1 diabetes. World J Diabetes 2025; 16(6): 104024

"My manuscript was charged teoce for eiditing with no discount on the second time. Otherwise service was good and i intend to submit ..." [Read more]

"My manuscript was charged teoce for eiditing with no discount on the second time. Otherwise service was good and i intend to submit my further articles with the journal in future and to work with the journal for future correspondence. I have other case reports and some larger studies in progress. " [Collapse]

Shah R, Belsha D, Thomas A, Alsweed A. High suspicion unveils Hidden pathology of pediatric gastrointestinal surgical cases misidentified as medical: Three case reports. World J Clin Pediatr 2025; 14(3): 104096

"We have published high-quality papers in World journals for quite some time and have thoroughly enjoyed the whole Publishing process. ..." [Read more]

"We have published high-quality papers in World journals for quite some time and have thoroughly enjoyed the whole Publishing process. BPG Publishing is doing a great service for the scientific community. The staff is very helpful and responsive. It was an unforgettable experience. Our group will be happy to cooperate with BPG Publishing Group in all possible ways. The quality of published articles is superb and at par with other international journals. Many of my friends now prefer to publish their articles in World journals. " [Collapse]

Raza Y, Mubarak M, Memon MY, Alsulaimi MS. Update on molecular pathogenesis of Helicobacter pylori-induced gastric cancer. World J Gastrointest Pathophysiol 2025; 16(2): 107052

"We would like to express our sincere gratitude to the editorial board and reviewers of the World Journal of Diabetes for their valuable ..." [Read more]

"We would like to express our sincere gratitude to the editorial board and reviewers of the World Journal of Diabetes for their valuable time and dedication. With your continued support, we are confident that the journal will further advance scientific knowledge and contribute to better clinical outcomes in diabetes care worldwide. " [Collapse]

Huseynov A, Kuşlu Çicek SN. Trends and predictors of diabetes mellitus after living kidney transplantation: A retrospective study. World J Diabetes 2025; 16(6): 105069

"I am pleased to recount my experience with the World Journal of Clinical Oncology. The peer review process was thorough, constructive, ..." [Read more]

"I am pleased to recount my experience with the World Journal of Clinical Oncology. The peer review process was thorough, constructive, and timely, providing valuable feedback that significantly enhanced the quality of my manuscript. The editorial team was highly professional, ensuring a smooth and efficient publishing process. Overall, I am highly satisfied with the journal's commitment to maintaining high academic standards and supporting authors throughout the publication journey. " [Collapse]

Razaq L, Dhali A, Maity R, Faisal AR, Hafeez AS, Zaman A, Humayun MA, Faizan M, Shahid M, Majeed M, Singh P. Demographic trends in mortality due to ovarian cancer in the United States, 1999-2020. World J Clin Oncol 2025; 16(6): 108393

"Thank you for all the aid during the submission and publication process, which were rapid, and effective. I appreciate the opportunity ..." [Read more]

"Thank you for all the aid during the submission and publication process, which were rapid, and effective. I appreciate the opportunity to making progress in Medical Science through quality peer-reviewed papers. Last but not least, I suggest that you track PubMed indexing process/time and inform authors about it. I would publish again with Baishideng Publishing Group, particularly in World Journal of Diabetes. " [Collapse]

Medeiros GA, de Santana JBF, Zajdenverg L, Negrato CA. Is there a role for platelet indices in predicting poor glucoregulation in type 2 diabetes mellitus? World J Diabetes 2025; 16(6): 101173

"The peer review report for our manuscript is fair and objective.We very satisfied with peer review process. This journal deserves ..." [Read more]

"The peer review report for our manuscript is fair and objective.We very satisfied with peer review process. This journal deserves a rave review for its depth. It is a must-read for professionals in this field. We appreciate the time and effort reviewers have spent on our work. The reviewer’s comments are helpful and we have carefully revised the issues. " [Collapse]

Bai JC, Yang HX, Zhan CC, Zhao LQ, Liu JR, Yang W. Hydrogen alleviates right ventricular hypertrophy by inhibiting ferroptosis via restoration of the Nrf2/HO-1 signaling pathway. World J Cardiol 2025; 17(6): 104832

"Publishing with BPG was a positive and efficient experience. The review process was timely, and the feedback provided was concise, ..." [Read more]

"Publishing with BPG was a positive and efficient experience. The review process was timely, and the feedback provided was concise, constructive, and relevant. The open access model enhances visibility, ensuring broader readership and increased citation potential. Overall, it was a smooth and professionally rewarding publishing journey that I would recommend. " [Collapse]

Ilias I, Meristoudis G. Changing paradigms in evaluating adrenal incidentalomas: Bayesian evaluation of [¹⁸F]Fluorodeoxyglucose positron emission tomography use, honed on adrenocortical carcinoma. World J Clin Oncol 2025; 16(6): 106511

"Submission process to the journal is easy. But requesting language editing for every manuscript is cumbersome and costly. It is ..." [Read more]

"Submission process to the journal is easy. But requesting language editing for every manuscript is cumbersome and costly. It is difficult for authors from low income countries. If the journal request this certificate from only those with poor grading for language, it would be helpful. The peer review process took a long time because it was difficulty to find a suitable and willing reviewers. However all 4 peer reviewers did a comprehensive analysis which improved the quality of the article significantly. Publication process if fast and editing the proof several times in word format and PDF format was helpful to eliminate the errors. Allocated issue is in September, but journal published the online article in June. " [Collapse]

Karunanayake A, Rajindrajith S, Kumari MV, Devanarayana NM. Effects of body mass index on gastric motility: Comparing children with functional abdominal pain disorders and healthy controls. World J Clin Pediatr 2025; 14(3): 100306

"Dear editorial staff, hello! I am very grateful to you and thankful for all the work done! Thank you very much! I hope for further ..." [Read more]

"Dear editorial staff, hello! I am very grateful to you and thankful for all the work done! Thank you very much! I hope for further cooperation with you! For us, working with the journal was interesting, you respond very quickly to requests, questions, and are always in touch with the authors! You have a very professional team! I wish the journal of World Gastroenterology prosperity in the future! " [Collapse]

Smirnova OV, Sinyakov A, Kasparov EV. Application of Wuling powder in the treatment of ulcerative colitis complicated by depression as a new therapy principle. World J Gastroenterol 2025; 31(23): 106538

"Overall the peer review report was objective and gave constructive feedback, although there were elements of it that may have missed ..." [Read more]

"Overall the peer review report was objective and gave constructive feedback, although there were elements of it that may have missed the intention of our article. Overall the process went well and was smooth. The time from submission to publication was satisfactory. The editorial staff were responsive and helpful in preparing the manuscript. " [Collapse]

Wu YZ, Kudlak M, Garza M, Grieme A, Liu KS, Kwon JJ, Smith ER, Yatsynovich E, Bushe B. Swallowed topical steroid maintenance therapy for eosinophilic esophagitis: A systematic review and meta-analysis. World J Meta-Anal 2025; 13(2): 107171

"I am very satisfied with the entire publication process of the article. Thank you to all the editors and reviewers. It is much ..." [Read more]

"I am very satisfied with the entire publication process of the article. Thank you to all the editors and reviewers. It is much appreciated that teachers took time from their busy schedules to edit, review, and revise my article. I am extremely grateful for everyone's help throughout the process. I am satisfied with all the editors and evaluators of the entire article. Thank you all for your help. " [Collapse]

Shao LL, Li X, Wang LF. Role of neutrophil-to-lymphocyte, platelet-to-lymphocyte, and monocyte-to-lymphocyte ratios in rectal cancer prognosis. World J Gastrointest Surg 2025; 17(6): 106813

"The entire process of manuscript submission, peer review process is swift and easy to follow. The editorial and reviewers comments ..." [Read more]

"The entire process of manuscript submission, peer review process is swift and easy to follow. The editorial and reviewers comments were very helpful in improving the overall quality of the manuscript. The editorial team kept us communicating with us at every step of the peer review. The post production process was also very helpful and modern. We thank all the concerned persons for making this possible. " [Collapse]

Malakar S, Rungta S, Samanta A, Shamsul Hoda U, Mishra P, Pande G, Roy A, Giri S, Rai P, Mohindra S, Ghoshal UC. Understanding acute kidney injury in cirrhosis: Current perspective. World J Hepatol 2025; 17(5): 104724

"The whole process including submission, external peer review was superb. The expert comments by the editor and the reviewers helped ..." [Read more]

"The whole process including submission, external peer review was superb. The expert comments by the editor and the reviewers helped us to improve the scientific quality of our manuscript. The post-production process was also immaculate. The editorial team helped us in no time whenever we reached out to them for any issues. We thank all the persons involved for making this possible. " [Collapse]

Samanta A, Ray G. Hepatic glycogen storage disease: Deciphering the genotype-phenotype conundrum. World J Clin Pediatr 2025; 14(3): 103415

"The review process was swift and smooth. The valuable comments by the reviewers definitely helped in improving the overall quality ..." [Read more]

"The review process was swift and smooth. The valuable comments by the reviewers definitely helped in improving the overall quality of the manuscript. The communication by the editorial team was on time and very helpful. We had some difficulty in editing the figures of our manuscript regarding which we reached out to the editorial team. The team very gracefully helped us in solving the problems, which we felt is very commendable. " [Collapse]

Ghosh U, Samanta A. Monogenic inflammatory bowel disease: An unfolding enigma. World J Clin Pediatr 2025; 14(3): 107165

"We sincerely thank the editorial team and the journal for their prompt, professional, and thoughtful support throughout the peer-review ..." [Read more]

"We sincerely thank the editorial team and the journal for their prompt, professional, and thoughtful support throughout the peer-review and revision process. The clear guidance, constructive feedback, and timely communication were truly appreciated. We would be honored to collaborate with your esteemed journal again in the future and contribute further to the scientific community. " [Collapse]

Luong TV, Hoang TA, Pham NN, Nguyen STM, Tran QB, Nguyen HM, Doan TC, Ho BA, Dang HNN. Eosinophilic myocarditis due to parasitic infection: A case-based minireview. World J Cardiol 2025; 17(6): 107729

"The online submission system is overly complicated, with certain requirements being particularly bewildering. For instance, it is ..." [Read more]

"The online submission system is overly complicated, with certain requirements being particularly bewildering. For instance, it is necessary to provide a variety of supporting documents, such as documents indicating the unit's agreement to publish articles and documents suitable for statistical analysis. Some of the requirements for supporting documents are excessively burdensome and lack relevance. " [Collapse]

Wang B, Ge JY, Wu JN, Xu JH, Cao XH, Chang N, Zhou X, Jing PB, Liu XJ, Wu Y. Endothelin A receptor in nociceptors is essential for persistent mechanical pain in a chronic pancreatitis of mouse model. World J Gastroenterol 2025; 31(23): 103848

"The entire process from submission to review is truly exceptional and seamless. We are especially thankful to the Editorial Assistant ..." [Read more]

"The entire process from submission to review is truly exceptional and seamless. We are especially thankful to the Editorial Assistant for their remarkable dedication, tirelessly editing the proof multiple times to ensure perfection. Their professionalism, attention to detail, and prompt communication made the experience outstanding. The editorial team’s commitment to quality, coupled with their supportive and collaborative approach, greatly enhanced our work. We deeply appreciate the thorough feedback, timely responses, and unwavering support throughout. Thank you for your outstanding efforts! " [Collapse]

Das BB, Aggarwal V, Deshpande SR. Navigating women with congenital heart disease during pregnancy: Management strategies and future directions. World J Cardiol 2025; 17(6): 106295

18923 items Read more >>

Article Quality Tracking-Peer-Review

"The study investigates phenotypic attributes and survival in mismatch repair deficient/microsatellite instability-high ..." [Read more]

"The study investigates phenotypic attributes and survival in mismatch repair deficient/microsatellite instability-high (MMR-deficient/MSI-H) colorectal carcinomas, a clinically relevant topic with clear translational implications. The retrospective design and focus on survival outcomes align with established research frameworks in oncology. This study provides valuable insights into MMR-deficient/MSI-H colorectal cancer, but enhancements in ethical documentation, statistical rigor, and methodological transparency are needed to strengthen its credibility. Addressing these gaps will not only improve the manuscript’s scientific quality but also position the findings to influence clinical practice. The authors are encouraged to prioritize multivariable analysis, standardized reporting, and contemporary literature integration to maximize the study’s impact." [Collapse]

Mehta A, Bansal D, Tripathi R, Anoop V. Phenotypic attributes and survival in mismatch repair deficient/microsatellite instability-high colorectal carcinomas. World J Clin Oncol 2025; 16(6): 104243

"This is a very nice case that illustrates the Worldwide Problem that Medicine has with Bariatric Surgery when it is not properly ..." [Read more]

"This is a very nice case that illustrates the Worldwide Problem that Medicine has with Bariatric Surgery when it is not properly indicated. The problem with obesity is that it has been tried to be solved with bariatric surgery alone. Obesity and overweight has caused a lot of health problems but most importantly are gastrointestinal symptomatology which is mostly attributed to a higher BMI. The solution to obesity is not surgery." [Collapse]

Cass K, Leggett A, Gibson DG. Diagnostic dilemma of avoidant/restrictive food intake disorder after bariatric surgery: A case report and review of literature. World J Clin Cases 2025; 13(24): 106941

"This study comparatively analyzed cancer incidence data between China and the global context in 2022, aiming to reveal disparities ..." [Read more]

"This study comparatively analyzed cancer incidence data between China and the global context in 2022, aiming to reveal disparities in cancer burden through multidimensional analysis of factors including gender, geographic distribution, and economic levels, while exploring risk factors associated with high-incidence cancer types. These findings provide a foundation for formulating targeted prevention and control strategies." [Collapse]

Hu D, Yu J, Feng J, Liu P, Chen JM, Zhang HL. Comparison and trend analysis of cancer incidence in China and globally in 2022. World J Clin Oncol 2025; 16(6): 107016

"(1) The study adopted a retrospective cohort design with a sample size of 102 adult AML patients, which meets statistical requirements. ..." [Read more]

"(1) The study adopted a retrospective cohort design with a sample size of 102 adult AML patients, which meets statistical requirements. However, the sample size may be insufficient for subgroup analyses (e.g., FAB-M2 subtype had only 44 cases) . (2) While the study clearly reported negative results (e.g., no significant association between SOX11 expression and CR, OS/DFS), it lacked biological justification for the SOX11 high/low expression grouping criteria . (3) Statistical analyses appropriately used Mann-Whitney tests and Kaplan-Meier survival methods for nonparametric data characteristics, but failed to implement multiple testing corrections (e.g., Bonferroni adjustment) . (4) This work validated SOX11's association with FLT3-ITD mutations and FAB-M2 subtype in AML, proposing its potential as a stratification marker for high-risk patients. However, functional experiments (e.g., CRISPR knockout/overexpression) are required to verify SOX11's oncogenicity and synergistic effects with FLT3-ITD in AML pathogenesis . Methodologically, the study demonstrated good standardization and result transparency, but was limited by sample size constraints and insufficient mechanistic exploration depth ." [Collapse]

Abdel Aziz RS, Radwan EM, Fouad AM, Abdellateif MS, Elfishawi S. Clinical significance of the transcription factor (SOX11) expression in the bone marrow of acute myeloid leukemia patients. World J Clin Oncol 2025; 16(6): 107271

"(1) Objectivity and Credibility: The research design is rigorous and the data supports the conclusions, but confounding factor ..." [Read more]

"(1) Objectivity and Credibility: The research design is rigorous and the data supports the conclusions, but confounding factor correction analysis needs to be added. (2) Scientific Value: For the first time, a systematic comparison of the lymph node characteristics and survival associations of MMR-D/MSI-H and MMR-P/MSS CRC was made, providing new basis for immunotherapy stratification. (3) Priority for Improvement: The results need to be verified through prospective cohort studies, and the clinical transformation pathways of LNY/LNR as prognostic markers need to be explored." [Collapse]

Mehta A, Bansal D, Tripathi R, Anoop V. Phenotypic attributes and survival in mismatch repair deficient/microsatellite instability-high colorectal carcinomas. World J Clin Oncol 2025; 16(6): 104243

"Objectivity: Moderate. The topic discussed in this study is actually a legacy topic, so the publication bias is obvious. Credibility ..." [Read more]

"Objectivity: Moderate. The topic discussed in this study is actually a legacy topic, so the publication bias is obvious. Credibility & Scientific quality: There are 2 papers included in this manuscript were reported on Pubpeer. Actually, there is one big problem for every meta-analysis article: There are too many fake papers published and indexed in various SciDatabases. " [Collapse]

Zheng XD, Li HY, Gao SY, Wang Q, Liu JB. High hypoxia inducible factor-1α expression is associated with reduced survival in patients with breast cancer: A meta-analysis. World J Clin Oncol 2025; 16(6): 105691

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

Younus A, Liu Y, Connor EE, Wu ZY, Lee H, Fu ZY. Segmental atrophy of the liver: Review of a rare pseudotumor. World J Clin Cases 2025; 13(24): 107825

"The ethical approval meets requirements. The study obtained approval (CE24431B) from Taichung Veterans General Hospital. The methods ..." [Read more]

"The ethical approval meets requirements. The study obtained approval (CE24431B) from Taichung Veterans General Hospital. The methods are effective and can be repeated by fellow researchers. They conducted a robust retrospective cohort using the TriNetX database, which harmonizes EHR data across 80 U.S. healthcare organizations. Besides, the inclusion and exclusion criteria are clear. The results of this study are authentic, reliable and validate the initial hypothesis. The tables, graphs, and figures were constructed and annotated well. But one mistake was presented in Table 3. Gestational hypertension HR typo ("HR: 1.936(1.844,0.033)" – "0.033" likely should be "2.033"). The biostatistics data was generally right. However, more details of PSM and some sensitivity analyses (e.g., competing risks for mortality) are suggested to be added. Authors have cited key references to support the pathophysiological mechanisms and prior epidemiological relationship, as well as some recent references. I suggest adding recent reviews on PIH-related metabolic dysfunction. The language is generally clear, concise, and logically structed." [Collapse]

Shih YH, Yang CY, Lung CC. Long-term risk of diabetes following hypertensive disorders of pregnancy: A retrospective cohort study. World J Diabetes 2025; 16(6): 105080

"This was prospective study investigating factors that could potentially influence mesalamine adherence in patients with ulcerative ..." [Read more]

"This was prospective study investigating factors that could potentially influence mesalamine adherence in patients with ulcerative colitis (UC), highlighting the impact of shared-decision-making on treatment outcomes. Basically, the results of the study indicate that when patients are involved in choosing their medication formulation, particularly granules, their adherence significantly improves, leading to better disease activity control. While acknowledging some limitations, such as reliance on self-reported adherence and potential participant dropout, the findings emphasize the importance of patient-centered care and accommodating individual preferences in long-term UC management. Ultimately, the study suggests that integrating shared-decision-making into routine gastroenterology practice might enhance adherence and overall outcomes. Regarding specific aspects: The ethical approval process appears to meet standard requirements based on the information provided. The study was reviewed and approved by the Ethics Committee of the North Rhine Chamber of Physicians, and registered on ClinicalTrials.gov. All study participants provided signed informed consent before study enrollment. Patient data were entered into an online electronic database using the double data entry method. The experimental method is described with sufficient detail to assess its effectiveness and potential for reproducibility. Basically, this was a 12-month, prospective, multicenter, non-interventional cohort study conducted at 113 specialty gastroenterology practices in Germany. The study design allowed for the collection of real-world data without formal interventions, which is highlighted as a strength. Eligibility criteria were clearly defined, and the inclusion of patients initiating or re-initiating mesalamine treatment in routine practice across Germany enhances the real-world applicability of findings. Decisions about diagnostic procedures and treatment were made by the treating physician according to patients’ clinical needs and independently of the study, ensuring routine clinical practice was observed. Disease activity was assessed using the partial Mayo score, with scores ranging from 0 to 9. Patient knowledge of UC was assessed using a self-developed, patient-administered questionnaire with two parts: self-rating and nine yes/no questions grouped into poor, moderate, or good/very good categories. Adherence was assessed using a self-developed, patient-administered questionnaire with a visual analogue scale (VAS). The reliance on a self-developed, self-reported VAS for adherence is noted as a potential limitation as it tends to overestimate adherence, though it is considered a simple and realistic measurement often used in practice. Patient involvement in treatment decision-making was not directly measured but inferred as a "proxy": instances where patients received their preferred mesalamine formulation were considered cases of shared decision-making. This is explicitly stated as an oversimplification and a limitation of the study. The authors provide information on the biostatistical methods used and present numerical results. The description of biostatistical methods and reported results appears to be correctly conducted. The results are presented clearly, supporting the study's aims and partially validating its hypothesis. However, the authors acknowledge that if all lost-to-follow-up patients are assumed to have suboptimal adherence, the rates drop dramatically at Visit 3, aligning more with previous literature. This demonstrates authenticity in acknowledging potential biases. Patient knowledge of UC (self-estimated or objectively measured) showed no significant association with adherence. Patients reporting good adherence experienced significant improvements in disease activity over 12 months. Patients who received their preferred formulation experienced continuous improvement in pMayo scores over 12 months. The figures, tables, and the diagram are clear and provide important information. The references provided suggest a reasonable approach to literature review on the subject., presenting relevant sources. There is no direct evidence to suggest self-citation, omission, mis-citation, or over-citation. The language used in the article is generally clear, concise, and grammatically correct. The study explicitly details its limitations in the "Strengths and limitations of the study" section. " [Collapse]

Kruis W, Jessen P, Morgenstern J, Reimers B, Müller-Grage N, Bokemeyer B. Shared decision-making improves adherence to mesalamine in ulcerative colitis: A prospective, multicenter, non-interventional cohort study in Germany. World J Gastroenterol 2025; 31(22): 101915

"Authors studied a clinically important yet underexplored aspect of young-onset type 2 diabetes mellitus (T2DM): the association between ..." [Read more]

"Authors studied a clinically important yet underexplored aspect of young-onset type 2 diabetes mellitus (T2DM): the association between vitamin D (VitD) status and apolipoprotein A1 (apoA1); a major component of HDL cholesterol with established cardioprotective properties. The study is one of the first to evaluate the relationship between VitD and apoA1 specifically in young-onset T2DM, a population at heightened risk for early cardiovascular morbidity and mortality. Since apoA1 plays a critical role in reverse cholesterol transport and HDL function, its association with VitD status provides a potential mechanistic link between VitD deficiency and increased cardiovascular risk in young-onset T2DM patients. However, the thresholds for “severe” VitD deficiency and the proportion of individuals in each deficiency category could be more clearly reported for better clinical applicability." [Collapse]

Hu Y, Shao LN, Zheng J, Zhang XM, Song YX, Xing YB. Vitamin D deficiency is associated with apolipoprotein A1 levels in patients with young-onset type 2 diabetes mellitus. World J Diabetes 2025; 16(6): 105558

"Li et al's work is a narrative review article focusing on the emerging role of ferroptosis in the pathogenesis of diabetic ..." [Read more]

"Li et al's work is a narrative review article focusing on the emerging role of ferroptosis in the pathogenesis of diabetic cardiomyopathy (DCM) and its potential as a therapeutic target. Ferroptosis inhibitors (e.g., ferrostatin-1, liproxstatin-1, and iron chelators) have demonstrated protection against lipid ROS accumulation and reduction of cardiac injury and fibrosis in preclinical models. Ferroptosis is a cutting-edge area of research with growing relevance in diabetic complications. The review links molecular pathways (GPX4, ACSL4, iron metabolism) to clinical manifestations of DCM. Highlights ferroptosis inhibition as a potentially novel and actionable intervention for a currently untreatable condition. Justifies the need for alternative treatments beyond glycemic control in DCM. These agents are being explored for iron overload cardiomyopathies and may be repurposed or tailored for DCM." [Collapse]

Li GZ, Liu JY, Zhou H. Ferroptosis: A novel therapeutic target for diabetic cardiomyopathy. World J Diabetes 2025; 16(6): 104665

"Authors studied an important limitation in diabetes management: the inadequacy of HbA1c in fully capturing glycemic control, ..." [Read more]

"Authors studied an important limitation in diabetes management: the inadequacy of HbA1c in fully capturing glycemic control, particularly in patients with type 1 diabetes (T1D). The authors introduce and validate the Glycemia Risk Index (GRI) as a more holistic tool by integrating data from continuous glucose monitoring (CGM). Study results indicated that GRI showed strong inverse correlation with time in range (TIR) (r = -0.90) and positive correlations with time below range (TBR), time above range, and glycemic variability (CV)—metrics that HbA1c poorly reflects. Each 1% increase in TBR or CV substantially raises the GRI, highlighting its sensitivity to dangerous glycemic patterns that HbA1c alone would miss. While the GRI is statistically elegant, its ease of use and interpretation by patients and non-specialist clinicians remain unexplored. User-friendliness is critical for widespread adoption." [Collapse]

"Authors studied an under-researched probiotic, Acetobacter pasteurianus, linking it with diabetes treatment via lipid metabolites, ..." [Read more]

"Authors studied an under-researched probiotic, Acetobacter pasteurianus, linking it with diabetes treatment via lipid metabolites, which is both innovative and timely given the rising interest in functional microbiota-derived therapeutics. The findings lay the groundwork for developing next-generation functional probiotics or postbiotics focused on metabolic diseases, particularly type 2 diabetes. While CoQ9 and OA were identified as hypoglycemic agents in the work, their precise molecular mechanisms of action (e.g., insulin sensitization, beta-cell preservation, or anti-inflammatory effects) remain unexplored sufficiently. No adequate data on signaling pathways (e.g., AMPK, PI3K/Akt) is included, which would strengthen the findings. " [Collapse]

Xu WY, Zhou WT, Luo JZ, Jiang YY, Zhang K, Zhang SY, Liu PS, Wei HY, Huang YQ. Lipid metabolism of Acetobacter pasteurianus and its main components with hypoglycemic effects. World J Diabetes 2025; 16(6): 103370

"None Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according ..." [Read more]

"None Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria. Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria Please make a specific and meaningful evaluation on the objectivity, credibility and scientific quality of the article according to above listed criteria" [Collapse]

Sun M, Yu J, Zhou JW, Ye M, Ye F, Ding M. Can ChatGPT and DeepSeek help cancer patients: A comparative study of artificial intelligence models in clinical decision support. Artif Intell Cancer 2025; 6(1): 106356

"Thanks for your interesting article. I think some points in this article should be considered. The paper provides MAILE primarily ..." [Read more]

"Thanks for your interesting article. I think some points in this article should be considered. The paper provides MAILE primarily narrative and theoretical foundations, much of the corroborative evidence coming from studies on generic isometric or core stabilization exercises. Although the authors themselves point out that direct empirical proof of MAILE is limited, no randomized controlled trials are available to contrast it with other core stabilization protocols. It is difficult to determine whether MAILE has any real clinical advantage or if it is simply a re-packaging of what is currently done, thus, in the lack of such comparisons. Additionally, besides subjective outcome measures like pain scales and questionnaires, objective physiological indicators like electromyography, motion analysis, or ultrasound imaging are desperately required in order to confirm that MAILE actually activates the assumed musculature as hypothesized. Identification of predictors of successful response to MAILE is another area that would benefit from more light. While the correlations reported (e.g., aberrant movement patterns, postpartum status, or positive Trendelenburg sign) are logical, they appear more based on the overall rehabilitation literature rather than specifically proven for MAILE. " [Collapse]

Syed Y, Hassan MA, Kalayil RM, Othman OA, Mekkodathil A, El-Menyar A. Promising technique for managing nonspecific chronic low back pain using multi angular isometric lumbar exercise. World J Orthop 2025; 16(5): 104425

"AI is usefull a lot in many fields. ARLD is common in many countries with cirrhosis complication. The article with new idea has ..." [Read more]

"AI is usefull a lot in many fields. ARLD is common in many countries with cirrhosis complication. The article with new idea has shown that using AI in ARLD management is very effective. Hopefully in the future many hospitals and medical centers will use AI in ARLD management to demonstrate effectiveness. " [Collapse]

Chen ML, Jiao Y, Fan YH, Liu YH. Artificial intelligence for early prediction of alcohol-related liver disease: Advances, challenges, and clinical applications. Artif Intell Gastroenterol 2025; 6(1): 107193

"The benefits of PRF in regulating innate immunity and encouraging wound healing have been covered in this editorial. PRF is a possible ..." [Read more]

"The benefits of PRF in regulating innate immunity and encouraging wound healing have been covered in this editorial. PRF is a possible treatment strategy for improved wound healing. It is a useful tool in therapeutic settings because of its ability to effectively promote tissue regeneration and modify innate immunity. PRF has the potential to greatly enhance patient outcomes and lessen the burden related to wound care as long as research into its processes and uses is conducted. The authors supported their manuscript by one figure and one table." [Collapse]

Mohammadi S. Innate immunity and wound repair: The platelet-rich fibrin advantage. World J Biol Chem 2025; 16(2): 107195

"In this manuscript, the authors provided a lengthy conclusion. They found that, while CQ and HCQ have shown promise in the treatment ..." [Read more]

"In this manuscript, the authors provided a lengthy conclusion. They found that, while CQ and HCQ have shown promise in the treatment of autoimmune diseases, there are several concerns and disputes surrounding their use. Although these drugs can help cure autoimmune illnesses, their use must be carefully considered in light of the benefits and drawbacks. The authors also stated that more study is needed to fully understand the therapeutic potential of CQ and HCQ in autoimmune diseases, maximize its use in clinical practice, and develop safer and more efficient treatments. In addition, the authors showed two nice figures." [Collapse]

Al-Hamadani M, Darweesh M, Mohammadi S, Al-Harrasi A. Chloroquine and hydroxychloroquine: Immunomodulatory effects in autoimmune diseases. World J Biol Chem 2025; 16(2): 107042

"In an effort to transform the treatment of Parkinson's disease and enhance patient outcomes, this review addressed preclinical ..." [Read more]

"In an effort to transform the treatment of Parkinson's disease and enhance patient outcomes, this review addressed preclinical achievements, long-term safety issues, and ethical considerations while highlighting the importance of stem cell therapy in neuroregeneration. Figures 1 and 2 are strong highlights in this manuscript, since Figure 1 depicts the classification of stem cells. As a result, this publication provided fundamental information regarding different types of stem cells and their applications in therapy." [Collapse]

Mokhtari YG, Varnava I, Kyrgiannis K, Ampatsidou V, Giakoumettis D. Stem cell therapy for Parkinson’s disease: A new hope for neural regeneration. World J Biol Chem 2025; 16(2): 106850

"In recent years, to enhance the diagnostic capability of colonoscopy in detecting polyps in the large intestine, tiny ones, various ..." [Read more]

"In recent years, to enhance the diagnostic capability of colonoscopy in detecting polyps in the large intestine, tiny ones, various computer-aided detection (CADe) systems have been increasingly utilized to improve the diagnostic accuracy of colonoscopy. In the study in question, the authors investigated precisely this possibility of CADe by conducting a meta-analysis of five relevant studies involving 1,624 examinees. They found that the adenoma missing rate was significantly lower in the group that underwent CADe compared to the group that underwent routine colonoscopy for small neoplasms. Interestingly, although the overall adenoma detection rate was not different between the two groups, it was higher in the group that underwent CADe during the first examination, suggesting that CADe significantly reduces the adenoma missing rate and polyp missing rate while improving the adenoma detection rate during the initial passage of the endoscope, thus demonstrating its potential to enhance the performance of colonoscopy. In recent years, we have witnessed the explosive growth and integration of artificial intelligence (AI) into clinical practice. It has been increasingly incorporated into clinical practice as it improves the detection of small and advanced colonic adenomas. The existing data strongly support the clinical application of AI in colonoscopy, as it significantly improves the diagnostic accuracy of endoscopy while reducing the endoscopic workload. However, over the next few years, the impact of AI applications is expected to be determined with precision, not only in the field of endoscopy but also in other areas of medical science, concerning not only gastroenterologists but also the effectiveness of daily therapeutic interventions." [Collapse]

Wang SY, Gao JC, Wu SD. Artificial intelligence for reducing missed detection of adenomas and polyps in colonoscopy: A systematic review and meta-analysis. World J Gastroenterol 2025; 31(21): 105753

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Peer-Reviewers and Manuscript Statistics

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Peer-reviewers: 31825

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