Baishideng Publishing Group

Simsar M, Yuruk YY, Sahin O, Sahin H. Radiological insights into diverticulitis: Clinical manifestations, complications, and differential diagnosis. World J Radiol 2025; 17(8): 107463

"First and foremost, we extend our sincerest gratitude to the editorial team of your journal for their professionalism and efficient ..." [Read more]

"First and foremost, we extend our sincerest gratitude to the editorial team of your journal for their professionalism and efficient collaboration throughout the review process, from initial submission to final publication. Their efforts have been instrumental in disseminating our academic work.We are particularly grateful to the anonymous reviewers for their constructive feedback. Their insightful critiques and rigorous suggestions have not only enhanced the academic rigor of this paper but also deepened our appreciation for the meticulous nature of scientific research.As researchers, we embrace scholarly criticism with an open mind. The methodological limitations and data interpretation issues identified during the review process have been addressed through additional experiments and comparative literature analysis. This constructive "review-improvement" cycle is fundamental to advancing the academic community. " [Collapse]

Zhang RN, Cui JY, Zhao ZH, Li YT, Liu ZW, Zhang JY, Wei Q, Lu YM, Chen QP. Prevalence of sarcopenia in patients with surgical obstructive jaundice and its impact on clinical outcomes. World J Gastrointest Surg 2025; 17(8): 107209

"I would like to give my sincerely appreciation to the editors and work staffs for all your efforts during the process of my manuscript ..." [Read more]

"I would like to give my sincerely appreciation to the editors and work staffs for all your efforts during the process of my manuscript publication. I am very satified with all the steps in the review and editing process, and hope publish more works with your jounral in the future. Thanks you very much. " [Collapse]

Yang RH, Lin ZP, Dong T, Fan WX, Qin HD, Jiang GH, Dai HY. Magnetic resonance imaging-based radiomics signature for predicting preoperative staging of esophageal cancer. World J Radiol 2025; 17(8): 110307

"I am very satisfied with the process of publishing this paper. The external review was sent out very promptly, and the expert reviewers ..." [Read more]

"I am very satisfied with the process of publishing this paper. The external review was sent out very promptly, and the expert reviewers provided professional revision suggestions, which was very important for my later writing. The article was also published quickly, greatly saving our time. Overall, I am very satisfied with the submission and publication of this paper. If given the opportunity in the future, I would still choose your journal. " [Collapse]

Liu JM, Li Z, Qi LH, Chu BL, Deng ZX, Tang FY. Imaging features of appendiceal signet ring cell carcinoma with uterine implantation: A case report. World J Radiol 2025; 17(8): 110868

"We are happy with the submission. I hope that y the editor can provide us with additional invited papers. We look forward to working ..." [Read more]

"We are happy with the submission. I hope that y the editor can provide us with additional invited papers. We look forward to working with BPG. The reviewing process needs work. It takes numerous months before reviewers are found. The system could be improved by slimlining the entire submission process. Other journals take 1-2 for complete publication. " [Collapse]

Enaholo E, Okoye G, Musa M, Suleman A, Ojo O, Foti R, D’Esposito F, Giglio R, Tognetto D, Gagliano C, Zeppieri M. High-resolution optical coherence tomography for screening ocular surface tumors: Historical markers and future directions. World J Clin Cases 2025; 13(29): 108046

"I would like to express my sincere appreciation to the editorial team of the World Journal of Radiology for their professional and ..." [Read more]

"I would like to express my sincere appreciation to the editorial team of the World Journal of Radiology for their professional and efficient handling of my manuscript. The peer review process was rigorous, constructive, and timely, providing valuable comments that significantly improved the overall quality and clarity of the work. The communication with the editorial office was smooth and courteous, and the publication process was transparent and efficient, ensuring a positive experience from submission to final acceptance. I am grateful for the opportunity to publish in this journal and commend the editors, reviewers, and staff for their dedication to maintaining high academic standards and supporting authors throughout the process. " [Collapse]

Ren S, Qin B, Daniels MJ, Zeng L, Tian Y, Wang ZQ. Developing and validating a computed tomography radiomics strategy to predict lymph node metastasis in pancreatic cancer. World J Radiol 2025; 17(8): 109373

"Thank you very much for publication of this manuscript. I think period of peer review is very long. So, I'm very happy if period of ..." [Read more]

"Thank you very much for publication of this manuscript. I think period of peer review is very long. So, I'm very happy if period of peer review would be be shorter. On the other hand, I don't have other comments. I try to submit more articles to this journal of other journal in this company. Thank you very much. " [Collapse]

Usuda D, Furukawa D, Imaizumi R, Ono R, Kaneoka Y, Nakajima E, Sugawara Y, Shimizu R, Sakurai R, Matsubara S, Tanaka R, Suzuki M, Shimozawa S, Hotchi Y, Osugi I, Katou R, Ito S, Mishima K, Kondo A, Mizuno K, Takami H, Komatsu T, Nomura T, Sugita M. Purpureocillium lilacinum: A minireview. World J Clin Cases 2025; 13(29): 108582

"The editorial experience with the World Journal of Clinical Pediatrics was exceptionally smooth and professional. Communication from ..." [Read more]

"The editorial experience with the World Journal of Clinical Pediatrics was exceptionally smooth and professional. Communication from the editorial office was timely and helpful, submission guidelines were clear, and the peer review process was constructive. We sincerely appreciate the efficiency, guidance, and support provided, ensuring a seamless submission to decision journey. " [Collapse]

Omullo P, Nurani KM, Shahabi K, Emma O, Mutuku B. Congenital scoliosis with truncus arteriosus type 1 in a preterm neonate: A case report. World J Clin Pediatr 2025; 14(3): 106439

"The journal’s reputation for excellence is clearly reflected in your team’s dedication, and I truly appreciate the effort put into ..." [Read more]

"The journal’s reputation for excellence is clearly reflected in your team’s dedication, and I truly appreciate the effort put into ensuring a smooth and successful publication. Thank you for your hard work and support—it has been a pleasure working with you. I look forward to future opportunities to contribute to your esteemed journal. " [Collapse]

Zhou XL, Li Y, Xia W, Zheng YY, Wu AP. Advances in transcranial magnetic stimulation for psychological symptom management in Parkinson’s disease. World J Psychiatry 2025; 15(9): 108497

"I sincerely appreciate the seamless publication process of my article. From initial submission to final publication, every stage ..." [Read more]

"I sincerely appreciate the seamless publication process of my article. From initial submission to final publication, every stage reflected remarkable efficiency and attention to detail. The peer-review process was both rigorous and timely, with constructive feedback that genuinely strengthened the paper. Your editorial team’s prompt responses to queries and transparent communication set a gold standard for academic publishing. The copyediting precision—particularly in standardizing references and refining technical terminology—demonstrated expertise I rarely encounter elsewhere. I look forward to collaborating with your journal next time. " [Collapse]

Chen WY, Chen Q, Wang CC, Zhang CY, Chen SK, Meng ZQ, Han P, Dong S, Chen QW. Response rates, survival status and adverse events of placebo in randomized control trials for hepatocellular carcinoma: A meta-analysis. World J Hepatol 2025; 17(8): 108533

"My experience with the publishing process with Baishideng has been very intuitive and thorough. I am pleased with the level of ..." [Read more]

"My experience with the publishing process with Baishideng has been very intuitive and thorough. I am pleased with the level of expertise that has gone into generating a quality publication. The only improvement would be for the communication and notification for replies could be made more accessible to the authors trying to publish. " [Collapse]

Sabatose KW, Baker A, Kugler K, Delikat J, Jowers B, Kumar A, Aslam S, Buggs J, Machado-Denis C, Kemmer N, Dhanireddy K, Syed R. Patient factors in responders and non-responders treated with steroids for acute alcohol-associated hepatitis. World J Hepatol 2025; 17(8): 108677

"I am deeply honored to have the opportunity to collaborate with you. I would also like to express my sincere gratitude to all the ..." [Read more]

"I am deeply honored to have the opportunity to collaborate with you. I would also like to express my sincere gratitude to all the reviewers and editors for their thorough review and thoughtful revisions of my work. Their contributions have significantly enhanced the quality of this piece and provided invaluable guidance for our future efforts. " [Collapse]

Yan HH, Ding ZY, Wang LL, Zhong DD, Jin XF, Liu XC, Cai JT, Lu XL. Effects of early diet resumption on the incidence of complications following polypectomy: A randomized controlled trial. World J Gastrointest Surg 2025; 17(8): 108669

"We authors are thoroughly impressed with the peer review process and the prompt responsiveness demonstrated by your journal. The ..." [Read more]

"We authors are thoroughly impressed with the peer review process and the prompt responsiveness demonstrated by your journal. The meticulous attention to detail clearly reflects your publication’s strength. We extend our best wishes for the journal’s continued success and a steadily rising Impact Factor. We will be recommending more colleagues to submit their work to your esteemed publication. " [Collapse]

Gao XX, Xu XX, Chen P, He TX, Du CZ, Zhou Q, Zhou GF, Guo XW, Peng JR, Li HT. Rare complete replacement-type left hepatic artery originating from the left gastric artery: A case report. World J Hepatol 2025; 17(8): 110413

"Dear Editor, We would like to sincerely thank you for giving us the opportunity to publish our article in the World Journal of ..." [Read more]

"Dear Editor, We would like to sincerely thank you for giving us the opportunity to publish our article in the World Journal of Hepatology. Your professional support, as well as the assistance of your editorial team, has been both fair and highly valuable throughout the entire review and production process. We also extend our deep gratitude to the reviewers, whose constructive comments and insightful suggestions have significantly enhanced the quality and clarity of our manuscript. Their critical input helped us strengthen the scientific contribution of our work. It has been a privilege to collaborate with your esteemed journal, and we sincerely hope that this fruitful cooperation will continue in the future. Sincerely, Enver Zerem, Corresponding Author on behalf of all authors " [Collapse]

Zerem E, Kunosic S, Kurtcehajic A, Zerem D, Zerem O. Bile acids in metabolic dysfunction-associated steatotic liver disease. World J Hepatol 2025; 17(8): 108606

"I am satisfied with the overall peer-review process, including the presentation of tables, figures, and typesetting. However, I believe ..." [Read more]

"I am satisfied with the overall peer-review process, including the presentation of tables, figures, and typesetting. However, I believe there is room for improvement in the timeline to publication. In the case of this review article, the process took approximately 150 days, which I personally feel is longer than ideal. A shorter turnaround time would enhance the author experience and help maintain the relevance of the research. " [Collapse]

Singla N, Shantan V, Saraswat A, Singh AP. Advances in portal pressure measurement: Endoscopic techniques, challenges, and implications for liver transplantation. World J Hepatol 2025; 17(8): 107679

"We are grateful to the editors and reviewers for their insightful comments, which have significantly improved this manuscript. This ..." [Read more]

"We are grateful to the editors and reviewers for their insightful comments, which have significantly improved this manuscript. This case report highlights the importance of considering ectopic adrenal adenoma in the differential diagnosis of hepatic masses, particularly when conventional imaging features overlap with hepatocellular carcinoma. Our experience underscores the need for a comprehensive diagnostic approach—integrating clinical history, multi-modality imaging, hormonal evaluations, and histopathological confirmation—to avoid misdiagnosis of rare ectopic tumors. We hope this report raises awareness among clinicians about the potential pitfalls in diagnosing hepatic lesions and encourages a broader differential diagnosis that includes embryologically derived ectopic tissues. Special thanks to our institutional support and colleagues who contributed to the management of this patient. We believe this case will serve as a valuable reference for improving diagnostic accuracy in similar clinical scenarios. " [Collapse]

Qin MQ, Zhao YP, Xie JP. Ectopic adrenal gland in the liver leading to a misdiagnosis of hepatocellular carcinoma: A case report. World J Hepatol 2025; 17(8): 108443

"Thank you to the editors and reviewers for your diligent work and professional insights. The rigorous peer-review process has been ..." [Read more]

"Thank you to the editors and reviewers for your diligent work and professional insights. The rigorous peer-review process has been highly beneficial and greatly contributed to the quality of the manuscript. The publication process was clear and efficient, and I am very pleased with the final outcome. I wish the journal continued success and look forward to the opportunity to submit to your esteemed publication again in the future. " [Collapse]

Gao DJ, Zeng T, Chong YT, Li XH. Copper and hepatic lipid dysregulation: Mechanisms and implications. World J Hepatol 2025; 17(8): 107803

"My experience with the evaluation system of World Journal of Hepatology has been highly positive. The peer-review process was rigorous ..." [Read more]

"My experience with the evaluation system of World Journal of Hepatology has been highly positive. The peer-review process was rigorous yet constructive, with comments that were detailed, precise, and very helpful in improving the quality of the manuscript. The editorial workflow was efficient and transparent, and communication with the editorial office was always clear and timely. I particularly value the openness of the system, which allows access to peer-review reports and author responses, thereby reinforcing the credibility and scientific integrity of the journal. Overall, I consider the evaluation process to be exemplary and a strong contribution to maintaining high editorial and academic standards. " [Collapse]

Pestalardo ML, Bevilacqua CS, Amante MF. Vitamin A toxicity and hepatic pathology: A comprehensive review. World J Hepatol 2025; 17(8): 107738

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your ..." [Read more]

"Dear Chief Editor and Esteemed Reviewers, Greetings of the day. Thank you so very much for publishing our manuscript in your prestigious PubMed Journal. We are very much obliged for the great efforts done by the reviewers, editors and the publication team. Their actions had greatly improved the overall scientific and academic quality of our manuscript upto highest international standards. Hopefully this unique manuscript will garner lots of citation in the scientific community. Thanks for the opportunity. Best Regards, Dr . Arvind Kumar Morya MS(Gold Medalist) MNAMS Additional Professor & Unit-I Head Cataract, Glaucoma, Refractive, Squint Paediatric Ophthalmology and Medical Retina Services Associate Editor UKJOS, National Advisor IJO,GJCSRO Editorial Board Member IJOVS, WJCC, EC-Ophthalmology, DOS Times, Journal of HOS. Reviewer Elsevier, AIMDR and IJO Clinical Trial Expert Panel - CDSCO & Ministry of Health and Family Welfare Convenor - AIOS Adverse Event Committee Department of Ophthalmology All India Institute of Medical Sciences, Bibinagar Hyderabad, Telangana -508126 INDIA +91-8003996598 " [Collapse]

Parmar UPS, Morya AK, Gupta PC, Arora A, Verma N. Role of artificial intelligence-based ocular biomarkers in hepatobiliary diseases: A scoping review. World J Hepatol 2025; 17(8): 109801

"We wish to extend our sincere appreciation for the exceptionally efficient and rigorous peer-review process. The swift yet meticulous ..." [Read more]

"We wish to extend our sincere appreciation for the exceptionally efficient and rigorous peer-review process. The swift yet meticulous feedback provided by your reviewers and editors is truly commendable. This dedication not only upholds the highest scholarly standards but also significantly accelerates the dissemination of valuable research, making the publication journey a highly positive and rewarding experience for authors. Thank you for your outstanding commitment to excellence. " [Collapse]

Mei SB, Liu J, Wang Y, Hu P, Cao Q. Inferior mesenteric arteriovenous fistula: Three case reports. World J Gastrointest Surg 2025; 17(8): 108656

19401 items Read more >>

Article Quality Tracking-Peer-Review

"Authors have present case in learning mode for readers. IO in pregnancy is always challenging to manage as reflected in this ..." [Read more]

"Authors have present case in learning mode for readers. IO in pregnancy is always challenging to manage as reflected in this case. Subtle Clinical manifestations in this IO in pregnancy often overlook these as masked by pregnancy symptoms Adhesion obstruction aggravating during pregnancy having hormonal role is debatable Gravid uterus compression may be precipitaing factor. Conservative management is choice unless conditions desperately demand surgical intervention. " [Collapse]

Omullo FP, Anyango OS, Mutua BM, Odoyo MO, Gogo HM, Obung'a VO. Fatal small bowel perforation complicating intestinal obstruction in pregnancy: A case report. World J Clin Cases 2025; 13(29): 109406

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. ..." [Read more]

" The manuscript is written well. Its structure is appropriate for this type of article. Ethical approval form meets the requirements. Methods are appropriate and effective. Results are appropriate of methods and are authentic. Tables and biostatistics data are perfect. The references are adequate of topic. Language of article is satisfied." [Collapse]

"Estrogen has receptors for (ERα) and (ERβ), each of which is distributed in different tissues and has diverse physiological effects. ..." [Read more]

"Estrogen has receptors for (ERα) and (ERβ), each of which is distributed in different tissues and has diverse physiological effects. ERα plays an important role in the reproductive organs, bones, and mammary glands, while ERβ functions in skeletal muscles, the nervous system, and the immune system. The authors' data suggests that in liver cancer, ERα is involved in the growth of liver cancer, while the expression of ERβ may control the development and progression of liver cancer. This is very interesting data." [Collapse]

Groover S, Addison S, Nicks S, Mwangi M, Brooks A, Kaul A, Kaul R. Sex based relative expression of estrogen receptors and tumor necrosis factor-alpha in liver affects hepatitis C virus viral pathogenesis. World J Gastroenterol 2025; 31(32): 104277

"This is a well- written and presented rarely case report about Invasive inflammatory fibrotic polyp of the duodenum.This manuscript ..." [Read more]

"This is a well- written and presented rarely case report about Invasive inflammatory fibrotic polyp of the duodenum.This manuscript gives additional new knowledge to the existing literature. This interesting and rare case report has certain guiding significance for clinicians. I think that this manuscript is suitable and worth to publication." [Collapse]

Zhang FM, Ning LG, Wang JJ, Zhu HT, Feng MB, Chen HT. Invasive inflammatory fibrotic polyp of the duodenum: A case report. World J Gastrointest Surg 2025; 17(8): 107558

"The ethical approval meets requirements. The data obtained from the CCORD/ACCORDION trials (ClinicalTrials.gov identifier: ..." [Read more]

"The ethical approval meets requirements. The data obtained from the CCORD/ACCORDION trials (ClinicalTrials.gov identifier: NCT00000620). The methods are effective and can be repeated by fellow researchers. The inclusion and exclusion criteria are clear. The authors conducted a study of 10251 participants aged 40-79 years diagnosed T2DM who were followed up for nearly 10 years to investigate the association of METS-IR with incidence of adverse cardiovascular (CVD) events. The main results and tables of this study are authentic, reliable and validate the initial hypothesis. By using the Cox proportional hazards models, restricted cubic spline, stratified subgroup analyses, and C-statistic analyses, the positive association of METS-IR with incidence of adverse CVD events and enhanced risk assessment and prediction of CVD events by adding METS-IR were observed. The statistical analyses were correct. The graphs and figures were constructed and annotated well. One suggestion and confusion should be noted. (1) Suggestion: MACEs, CVD mortality and other outcomes should not be presented in the Table 1. (2) Confusion: In the Data collection and outcomes section, the MACEs was defined as a composite of cardiovascular mortality, nonfatal myocardial infarction (MI), and non-fatal stroke. So, I assumed that the number of MACEs should be equal to the sum of CVD mortality, non-fatal MI, and non-fatal stroke. However, in the Table 1, the number of MACEs was less than the sum of them. The authors should explain this. Authors have cited key references to support the pathophysiological mechanisms and prior epidemiological relationship, as well as the recent references. The language is generally clear, concise, and logically structed. One mistake should be written. The sentence “Further studies have indicated that biological aging the effects of METS-IR on all-cause and CVD mortality” is not fluent." [Collapse]

Xin Y, Peng NL, Xin CY, Liao JR, Hu XQ, Dong YH, Zhang XY. Metabolic score for insulin resistance is associated with adverse cardiovascular events in patients with type 2 diabetes. World J Diabetes 2025; 16(8): 108671

"This review explores the possible role of SARS-CoV-2 infection in the development of malignant neoplasms of the gastrointestinal ..." [Read more]

"This review explores the possible role of SARS-CoV-2 infection in the development of malignant neoplasms of the gastrointestinal system. The proposed mechanisms, as is the case in almost all types of malignant neoplasms, are related to chronic inflammatory processes, disturbances in cellular homeostasis, and possibly the integration of the virus into host cells. The significance of these observations is obvious, since if they are proven to be true, measures will need to be taken to systematically monitor patients who have contracted SARS-CoV-2. In their very interesting review, the authors also present some thoughts on the reliability of published studies linking SARS-CoV-2 infection with the development of digestive cancer. I would like to add one more doubt. Medical students learn that cancer is a multistage process with multiple causes on the one hand and a time-consuming process on the other. I am struck by the fact that the scientific community almost immediately adopts clinical or experimental evidence of carcinogenesis from a particular cause despite the generally accepted views I mentioned above. In any case, this subject is an extremely interesting subject worth consideration. I believe that in the near future, a number of epidemiological and basic research studies should be conducted to better understand whether this virus is really oncogenic and to further clarify possible mechanisms of carcinogenesis." [Collapse]

Miteva DG, Gulinac M, Peruhova M, Velikova T. Exploring the oncogenic potential of SARS-CoV-2 in the gastrointestinal tract. World J Gastroenterol 2025; 31(31): 105665

"Good article on an important topic. Well researched. Will act as a reference point for future articles on this subject. Use of ..." [Read more]

"Good article on an important topic. Well researched. Will act as a reference point for future articles on this subject. Use of Artificial intelligence to improve patient outcomes is the future. Author has taken good reference points and has written an unbiased article. More such articles and editorials are welcome." [Collapse]

Tasci B, Dogan S, Tuncer T. Artificial intelligence in gastrointestinal surgery: A systematic review. World J Gastrointest Surg 2025; 17(8): 109463

"An interesting article on tissue engineering with a good set of modern methods incl. immunochemistry and valuable data on ligament ..." [Read more]

"An interesting article on tissue engineering with a good set of modern methods incl. immunochemistry and valuable data on ligament regeneration using MSC seeded fibrous scaffolds. 1 Ethics: The ethical approval form provided by the author meets the requirements. 2 Methods: The experimental method effective and can be repeated. 3 Results: The results are true and authentic. 4 Figures and tables: The authors provide perfect tables, line charts and/or graphs. 5 Biostatistics: The authors provide perfect biostatistics data. 6 References: The authors scientifically and reasonably cite the latest references which are important in this field. 7 Language: The language in article correctly, clearly and concisely expresses the information? " [Collapse]

Yang CW, Zhang YQ, Chang H, Gao R, Chen D, Yao H. Aligned nanofiber scaffolds combined with cyclic stretch facilitate mesenchymal stem cell differentiation for ligament engineering. World J Stem Cells 2025; 17(8): 107124

"A good review with general information about MSCs and artificial intelligence and specific information about the application of ..." [Read more]

"A good review with general information about MSCs and artificial intelligence and specific information about the application of artificial intelligence in MSCs therapy. 1 Ethics: The ethical approval form provided by the author meets the requirements. 2 Methods: The experimental method effective and can be repeated. 3 Results: The results are true and authentic. 4 Figures and tables: The authors provide perfect tables, line charts and/or graphs. 5 Biostatistics: The authors provide perfect biostatistics data. 6 References: The authors scientifically and reasonably cite the latest references which are important in this field. 7 Language: The language in article correctly, clearly and concisely expresses the information? " [Collapse]

Choudhery MS, Arif T, Mahmood R. Applications of artificial intelligence in stem cell therapy. World J Stem Cells 2025; 17(8): 106086

"A good informative review with valuable general information in the Introduction and 2 first sections and specific information on ..." [Read more]

"A good informative review with valuable general information in the Introduction and 2 first sections and specific information on clinical cases about MSC therapy for lupus nephritis. Liu L, Behera TR, Wang QJ, Shen QQ. Advances in mesenchymal stem cell therapy for lupus nephritis. World J Stem Cells 2025; 17(8): 104930 [DOI: 10.4252/wjsc.v17.i8.104930]. 1 Ethics: The ethical approval form provided by the author meets the requirements. 2 Methods: The experimental method effective and can be repeated. 3 Results: The results are true and authentic. 4 Figures and tables: The authors provide perfect tables, line charts and/or graphs. 5 Biostatistics: The authors provide perfect biostatistics data. 6 References: The authors scientifically and reasonably cite the latest references which are important in this field. 7 Language: The language in article correctly, clearly and concisely expresses the information? " [Collapse]

Liu L, Behera TR, Wang QJ, Shen QQ. Advances in mesenchymal stem cell therapy for lupus nephritis. World J Stem Cells 2025; 17(8): 104930

"This is very interesting paper about gastrointestinal cancer after covid19 infection.After Covid 19 infection, an increase in ..." [Read more]

"This is very interesting paper about gastrointestinal cancer after covid19 infection.After Covid 19 infection, an increase in gastrointestinal cancer has been reported due to factors such as a weakened immune system,changes in the intestinal flora and a weakened gut barrier.If so, please tell me what kind of gastrointestinal cancer are most popular." [Collapse]

Miteva DG, Gulinac M, Peruhova M, Velikova T. Exploring the oncogenic potential of SARS-CoV-2 in the gastrointestinal tract. World J Gastroenterol 2025; 31(31): 105665

"1. Non operative treatment failure can be different in age groups 9 pediatric vs adult), types of appendicitis (complicated vs non ..." [Read more]

"1. Non operative treatment failure can be different in age groups 9 pediatric vs adult), types of appendicitis (complicated vs non complicated). 2. In case of appendicolith, the need for follow up visit and imaging considerations may inflate the health expenditure, cautioning the approach of neglecting the role of appendicolith in management strategies 3. Conclusion can avoid citations as it pertains to the manuscript discussion and represents the author's opinion as a take-home message " [Collapse]

Tian J. Appendicolith in non-operative management of acute appendicitis: Implications for recurrence and future directions. World J Clin Cases 2025; 13(28): 109664

"1. The Magnetic resonance cholangiopancreatography (MRCP) image is not available and can be included for correlation 2. A diagram ..." [Read more]

"1. The Magnetic resonance cholangiopancreatography (MRCP) image is not available and can be included for correlation 2. A diagram illustrating the surgical findings may be helpful in understanding the patient's anatomy better 3. Imaging on sonography (multiple gall stones) and intra op findings (single large 4 cm stone) appear to stand in contrast. " [Collapse]

Gupta AK, Surendranath A. Cholecysto-biliary fistula mimicking type 1 Mirizzi syndrome: A case report. World J Clin Cases 2025; 13(28): 108437

"1. The airway difficulty is not clearly described. The xray spine was normal. The intubation was not prolonged and was carried out ..." [Read more]

"1. The airway difficulty is not clearly described. The xray spine was normal. The intubation was not prolonged and was carried out smoothly. 2. In children with complex cervical spine lesions such as Klippel Feil syndrome, the intubation is more challenging due to the short neck and restricted neck mobility 3. Were other options such as sedation / local block / LMA considered?" [Collapse]

Lin XN, Chan WS, Lu CW. Airway management strategies in a pediatric patient with MURCS association: A case report. World J Clin Cases 2025; 13(28): 106852

"Cardiovascular complications and mortality remain the leading causes of death in T2DM. Investigating TyG-BMI (a composite index ..." [Read more]

"Cardiovascular complications and mortality remain the leading causes of death in T2DM. Investigating TyG-BMI (a composite index combining triglyceride-glucose index with BMI) is highly relevant, as it may better capture the combined impact of insulin resistance and obesity compared to TyG or BMI alone. While TyG has been studied, TyG-BMI is a relatively novel marker, and this research adds unique insights into its predictive role for cardiovascular outcomes and mortality. Authors reported that that TyG-BMI improved discriminative performance beyond TyG or BMI alone and it provided important evidence for clinical risk stratification." [Collapse]

Liu MJ, Xiang SM, Hu XQ. Triglyceride glucose-body mass index is associated with cardiovascular outcomes and overall mortality in type-2 diabetes mellitus patients. World J Diabetes 2025; 16(8): 108839

"The use of an RCT design is the gold standard for evaluating therapeutic interventions. Randomization minimizes allocation bias and ..." [Read more]

"The use of an RCT design is the gold standard for evaluating therapeutic interventions. Randomization minimizes allocation bias and balances potential confounders between groups, thereby strengthening internal validity. This is particularly valuable in DFU research, where outcomes are strongly influenced by multiple factors (glycemic control, vascular status, infection history). DFUs are a leading cause of hospitalization, morbidity, and amputation in diabetes. Exploring a low-cost, safe, and easily accessible adjunct therapy like vitamin D addresses an urgent unmet clinical need. The supplementation strategy (2000 IU cholecalciferol daily) is practical, inexpensive, and feasible to implement in most healthcare systems, enhancing translational impact. Authors didn't limit themselves to only wound size reduction but evaluated multiple endpoints such as infection incidence and severity (clinically meaningful, patient-centered outcomes) as primary outcomes and wound healing rate, serum vitamin D levels, immune biomarkers (cathelicidin, IL-6, TNF-α), and safety monitoring as secondary outcomes. This multidimensional approach allowed the authors to connect clinical outcomes with mechanistic pathways, thereby strengthening biological plausibility. Reduced infection rate, promoted wound healing, and strengthened immune responses in patients with DFUs are reported after vitamin D supplementation. " [Collapse]

Gao YQ, Gao YH, Xing JH. Vitamin D supplementation reduces infection rate and promotes wound healing in patients with diabetic foot ulcers. World J Diabetes 2025; 16(8): 108166

"Type 2 diabetes (T2D) is a global health burden, and lifestyle interventions remain foundational. The focus on meal replacements (MRs) ..." [Read more]

"Type 2 diabetes (T2D) is a global health burden, and lifestyle interventions remain foundational. The focus on meal replacements (MRs) addressed an area of growing clinical and research interest, particularly in weight and glycemic control. Authors aimed to provide a comprehensive scoping review, not only summarizing evidence on outcomes but also classifying meal replacement types, dosages, and adverse effects. This approach is clinically useful, as different formulations (low-calorie, diabetes-specific, protein-rich, etc.) may have different impacts. Large initial dataset (53,922 studies) screened down to 133 eligible studies, showing thoroughness. Categorization of interventions provides practical insights for clinicians. Both benefits (HbA1c reduction, weight loss, BMI changes) and risks (adverse events, tolerability) were reported in the systematic review. Authors concluded that most adverse events were mild (constipation being most frequent) is reassuring for safety considerations." [Collapse]

Lew LC, Mat Ludin AF, Abdul Manaf Z, Mohd Tohit N, Shahar S. Mapping evidence and identifying risks: A systematic scoping review of meal replacements in type 2 diabetes. World J Diabetes 2025; 16(8): 104371

"Carotid atherosclerosis is a major complication of T2DM, and identifying predictors of plaque formation is important for early risk ..." [Read more]

"Carotid atherosclerosis is a major complication of T2DM, and identifying predictors of plaque formation is important for early risk stratification and prevention of cardiovascular events. Authors xamined a broad set of clinical and biochemical parameters (glycemic markers, renal function indices, uric acid, lipid profile, etc.), giving a holistic picture of vascular risk in T2DM. IMT and plaque detection via ultrasound provide objective and clinically relevant endpoints, improving the translational value of the findings. Authors reported modifiable (FPG, HbA1c, SBP, SUA, UACR) and non-modifiable (age) risk factors, which can guide both clinical practice and patient education." [Collapse]

Shi L, Li NJ. Comprehensive analysis of risk factors associated with carotid plaque in patients with type 2 diabetes mellitus. World J Diabetes 2025; 16(8): 104180

"The article provides compelling long-term evidence that challenges traditional assumptions about appendicoliths in acute appendicitis. ..." [Read more]

"The article provides compelling long-term evidence that challenges traditional assumptions about appendicoliths in acute appendicitis. It highlights that their presence should not be viewed as a definitive predictor of failure in nonoperative management. Instead, it supports individualized, evidence-based clinical decision-making aimed at improving patient outcomes, reducing recurrence risks, and avoiding unnecessary surgical interventions, thereby promoting a more balanced, patient-centered approach to managing uncomplicated cases of acute appendicitis." [Collapse]

Tian J. Appendicolith in non-operative management of acute appendicitis: Implications for recurrence and future directions. World J Clin Cases 2025; 13(28): 109664

"The study by Ding et al., “TSC22D1 promotes liver sinusoidal endothelial cell dysfunction and induces macrophage M1 polarization in ..." [Read more]

"The study by Ding et al., “TSC22D1 promotes liver sinusoidal endothelial cell dysfunction and induces macrophage M1 polarization in non-alcoholic fatty liver disease,” investigates the role of TSC22D1 in NAFLD, demonstrating its involvement in endothelial dysfunction and macrophage M1 polarization, key factors in disease progression. The authors successfully address the molecular mechanisms underlying NAFLD, providing insights into potential therapeutic targets. However, the study is limited by its in vitro design and does not explore the clinical implications or validate findings in human subjects. Future research should include in vivo studies and clinical investigations to assess the therapeutic potential of targeting TSC22D1. Overall, the study offers significant mechanistic insights that advance the understanding of NAFLD while highlighting directions for future translational research. " [Collapse]

Ding W, Xu XQ, Wu LL, Wang Q, Wang YQ, Chen WW, Tan YL, Wang YB, Jiang HJ, Dong J, Yan YM, Xu XZ. TSC22D1 promotes liver sinusoidal endothelial cell dysfunction and induces macrophage M1 polarization in non-alcoholic fatty liver disease. World J Gastroenterol 2025; 31(31): 109605

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2265

Peer-reviewers: 33202

Manuscripts received today: 16

Manuscript reviews today: 33

Unhandled manuscripts today: 126

Active peer-reviewers today: 1044

Reviewer acceptance today: 39

Reviewer refusals today: 56

Total accepted manuscripts: 37452

Total rejected manuscripts: 42842

Total peer-reviewers: 4343355

Total submissions: 35690