Baishideng Publishing Group

Delgado Galan M, Quintanilla Lazaro E, Rabago Torre LR. Postcolonoscopy colorectal cancer: What we need to know in the age of screening and magnifying endoscopy techniques. World J Gastrointest Endosc 2025; 17(7): 107430

"The submission, review, and publication processes for this manuscript were remarkably efficient and well-organized. The online ..." [Read more]

"The submission, review, and publication processes for this manuscript were remarkably efficient and well-organized. The online submission system was user-friendly, allowing for seamless uploading of all required files and information. The editors provided prompt and clear communication throughout the process. The peer reviewers delivered thorough and constructive feedback in a timely manner, which greatly improved the quality of the manuscript. Revisions were handled smoothly, with clear instructions provided. " [Collapse]

Gadour E, Miutescu B, Okasha HH, Albeshir M, Alamri T, Ghoneem E, Burciu C, Popa A, Koppandi O, AlQahtani MS. Evolving role of endoscopic ultrasound in biliary stricture management: A meta-analysis and systematic review. World J Gastrointest Endosc 2025; 17(7): 108541

"We sincerely appreciate the efficient review process and the valuable feedback provided by the reviewers. The editorial team was ..." [Read more]

"We sincerely appreciate the efficient review process and the valuable feedback provided by the reviewers. The editorial team was supportive and communicative throughout. Although there was a slight delay in processing after the APC payment, which caused some concern, the overall experience was positive, and it was a pleasure to publish our case report in this journal. " [Collapse]

Shin SY, Yeon HJ, Lee SO, Lee JR, Leem G, Han SJ. Fatal air embolism during intestinal endoscopy in Kasai portoenterostomy for biliary atresia: A case report. World J Gastrointest Endosc 2025; 17(7): 105773

"Thank you to editor Lili and the editorial team for their prompt and helpful responses throughout the submission process, which enabled ..." [Read more]

"Thank you to editor Lili and the editorial team for their prompt and helpful responses throughout the submission process, which enabled the smooth publication of this innovative gastric preparation study. In our research, we found that drinking 550 mL of carbonated soft drink before MCE led to better and more sustained gastric filling for at least 10 minutes, compared to drinking 1000 mL of pure water, and may also promote gastric emptying. This provides a preliminary clinical evaluation of a novel gastric preparation regimen for MCE, demonstrating that carbonated soft drink offers superior and longer-lasting gastric filling than pure water. " [Collapse]

Zhu JH, Liu X, Zhou W, Xu XN, Sheng WD, Han YL, Qiu XO, Liu YW, Qian YY, Liao Z, Li ZS. Carbonated soft drink for gastric preparation for magnetically controlled capsule endoscopy: An open-label randomized controlled trial. World J Gastroenterol 2025; 31(24): 105823

"Our experience with the World Journal of Clinical Cases' evaluation and publication process has been exceptionally positive. We would ..." [Read more]

"Our experience with the World Journal of Clinical Cases' evaluation and publication process has been exceptionally positive. We would like to express our gratitude to the editorial team for their rapid communication and the remarkably smooth progression of our submission. For future enhancements, we recommend simplifying the user interface to improve user-friendliness. " [Collapse]

Cicek E, Karatepe YK, Kantarcı TR, Sahin TT. Demanding sleeve gastrectomy procedure in a patient with severe intraabdominal adhesions: A case report and review of the literature. World J Clin Cases 2025; 12(23): 104807

"Publishing with this journal was a highly positive experience. The peer review process was thorough yet constructive, offering ..." [Read more]

"Publishing with this journal was a highly positive experience. The peer review process was thorough yet constructive, offering insightful feedback that strengthened our manuscript. Communication with the editorial team was prompt and professional throughout. The submission platform was user-friendly, and timelines for review and publication were clearly communicated and adhered to. We felt supported and valued as contributors, and we appreciated the journal's commitment to scientific rigor and visibility. Overall, a smooth and rewarding experience. " [Collapse]

Ansari N, Twohig P. Silent sabotage: How hepatitis B virus-miR-3 disarms innate immunity through cGAS-STING suppression. World J Hepatol 2025; 17(6): 106493

"Thank you very much to the editors and reviewers of your journal for their recognition and support of our manuscript. We are truly ..." [Read more]

"Thank you very much to the editors and reviewers of your journal for their recognition and support of our manuscript. We are truly honored to have our case report published in your esteemed journal. This successful publication would not have been possible without your efficient and professional workflow and the hard work of everyone involved. Once again, we express our deepest gratitude to all of you. " [Collapse]

Ma TT, Lyu HR. Post-endoscopic retrograde appendicitis therapy stent impaction leading to exacerbation of appendicitis: A case report. World J Clin Cases 2025; 13(25): 106587

"This journal maintains high academic standards with a rigorous peer-review process, ensuring quality publications. It has a strong ..." [Read more]

"This journal maintains high academic standards with a rigorous peer-review process, ensuring quality publications. It has a strong reputation in its field, offering timely dissemination of research. The editorial team is professional and responsive. With a solid impact factor and global reach, it provides excellent visibility for authors. A reliable choice for impactful scholarly work. " [Collapse]

Xiao Y, Ren BC, Zhang T, Peng D, Min J. Factors influencing postoperative complications in patients with gastric cancer: A retrospective study. World J Gastrointest Surg 2025; 17(5): 101047

"The online submission system runs smoothly and easy to master for authours who use for the first time. The peer review report is ..." [Read more]

"The online submission system runs smoothly and easy to master for authours who use for the first time. The peer review report is helpful and objective. The anonymous peer review process is of high efficiency. The period of publication is rather short. The editors of the journal are very friendly and earnest. " [Collapse]

Hou XL, Chen J, Cui MH, Yang GB. Extensive idiopathic mesenteric phlebosclerosis presenting as intestinal pseudo-obstruction: A case report. World J Clin Cases 2025; 13(25): 105028

"It would be helpful to have a simpler way to submit files. Adding an easy drag-and-drop option can save time and reduce confusion. ..." [Read more]

"It would be helpful to have a simpler way to submit files. Adding an easy drag-and-drop option can save time and reduce confusion. Clear steps on how to upload files and a message to confirm the file was sent successfully would make the process smoother and less stressful for everyone, especially for those who are not very tech-savvy. " [Collapse]

Harna B, Arya S. Tramadol overdose in total knee arthroplasty: A case report. World J Clin Cases 2025; 13(25): 104742

"We are very satisfied with the editorial and peer review process. The editors and reviewers have provided no additional comments or ..." [Read more]

"We are very satisfied with the editorial and peer review process. The editors and reviewers have provided no additional comments or concerns regarding our manuscript. We appreciate the thorough and efficient review process, and we are pleased that our work meets the publication standards. We look forward to the next steps in the publication process. " [Collapse]

Sun Q, Wu JC, Chen X, Li DH, Li BR, Xiao NJ, Wang XY, Tu XZ, Ning SB, Sun T. Efficacy and safety of sirolimus in the treatment of gastrointestinal angiodysplasias. World J Gastroenterol 2025; 31(25): 105677

"Our recent experience with submitting and publishing our manuscript, titled "Nursing care of a patient with negative symptoms of ..." [Read more]

"Our recent experience with submitting and publishing our manuscript, titled "Nursing care of a patient with negative symptoms of schizophrenia who underwent tracheotomy: A case report," in the World Journal of Clinical Cases was exceedingly positive and surpassed our expectations. We extend our profound gratitude for the rigorous and constructive nature of the peer review process. The timely and highly perceptive feedback provided by the anonymous reviewers was greatly appreciated. Their comments, which were both critical and demonstrated a sophisticated understanding of our research domain, guided us in making significant improvements to the quality of our manuscript, enhancing the precision of our key information, and improving the clarity and overall impact of our findings. The editorial handling by the editorial team was also exemplary. Communication was consistently prompt, transparent, and highly professional at every stage, from initial submission decisions to post-acceptance production. Their efficiency ensured a smooth progression of our manuscript through all phases. Finally, the post-acceptance production team was swift and meticulous in preparing our article for publication. The entire process, from submission to online appearance, was surprisingly quick without compromising on quality checks. We are incredibly grateful for the opportunity to publish our work in the World Journal of Clinical Cases. We wholeheartedly recommend this journal to fellow researchers in Psychiatric nursing who are seeking a publishing venue that combines a streamlined submission process with an outstandingly supportive and rigorous peer-review and editorial experience. It truly contributes to advancing high-quality research within the field. " [Collapse]

Li JY, Liu XE, Li W, Wang LN. Nursing care of a patient with negative symptoms of schizophrenia who underwent tracheotomy: A case report. World J Clin Cases 2025; 13(25): 108124

"I was very satisfied with the overall editorial and publication process. The peer review was fair, constructive, and timely. The ..." [Read more]

"I was very satisfied with the overall editorial and publication process. The peer review was fair, constructive, and timely. The editorial office maintained clear communication throughout, and the revisions were handled efficiently. I did not encounter any particular difficulties, and I appreciate the professionalism and responsiveness of the editorial team. " [Collapse]

Lee AY, Lim SG, Cho JY, Kim S, Lee KM, Shin SJ, Noh CK, Lee GH, Hur H, Han SU, Son SY, Song JH. Comparison of treatment strategies for submucosal tumors originating from the muscularis propria at esophagogastric junction or cardia. World J Gastroenterol 2025; 31(23): 106261

"The peer review process and publication process were compact and soon. In general, we were satisfied with the whole process of the ..." [Read more]

"The peer review process and publication process were compact and soon. In general, we were satisfied with the whole process of the course of submission. In addition, we would like to suggest our colleagues to submit their works to the Journal according to the efficient managements from the editorial office. " [Collapse]

Chang YC, Liu WN, Lin F, Lin GM. Mood alteration and heart rate variability in patients with cancer on treatment. World J Cardiol 2025; 17(6): 107114

"We feel extremely honored and delighted to have our article published in the World Journal of Gastroenterology. The entire submission ..." [Read more]

"We feel extremely honored and delighted to have our article published in the World Journal of Gastroenterology. The entire submission process was smooth and efficient, and the editorial team was incredibly supportive and professional. Their constructive feedback significantly improved our manuscript. We truly appreciate the positive experience and the platform this journal provides for disseminating important research. " [Collapse]

Huang SS, Chen W, Vaishnani DK, Huang LJ, Li JZ, Huang SR, Li YZ, Xie QP. Leucine-rich repeat-containing protein 19 suppresses colorectal cancer by targeting cyclin-dependent kinase 6/E2F1 and remodeling the immune microenvironment. World J Gastroenterol 2025; 31(25): 107893

"We sincerely thank the editorial board and reviewers of the World Journal of Gastroenterology for their constructive comments and ..." [Read more]

"We sincerely thank the editorial board and reviewers of the World Journal of Gastroenterology for their constructive comments and professional handling of our manuscript. The review process was thorough, transparent, and timely, contributing to the refinement and clarity of our work. We are pleased that our study has been accepted for publication in this well-regarded journal. " [Collapse]

Gajovic NM, Jovanovic IP, Jocic MV, Stojanovic B, Corovic IF, Todorovic N, Simovic Markovic BJ, Amedei A. Exploring the impact of galectins on liver cancer: From immunopathogenesis to potential targets. World J Gastroenterol 2025; 31(25): 107260

"Thank you for publishing our work. We are grateful for the opportunity to contribute to the scientific community through your esteemed ..." [Read more]

"Thank you for publishing our work. We are grateful for the opportunity to contribute to the scientific community through your esteemed journal. The publication process was smooth and professional, and we appreciate the editorial team's guidance. We hope our findings will spark further research and dialogue, and we look forward to future collaborations with your journal. " [Collapse]

Basit A, Noor S, Ahmad SA, Noor N, Maryam R, Basil AM. Otitis media with effusion and hearing outcomes - Myringotomy vs myringotomy and tympanostomy: A comparative study. World J Otorhinolaryngol 2025; 12(1): 109355

"The entire process took too long from submission to publishing. In particular, it took too long from the submission of the revised ..." [Read more]

"The entire process took too long from submission to publishing. In particular, it took too long from the submission of the revised paper (according to peer review) and the final publishing. We are satisfied with overall quality of the journal and the edited paper, but it’s not the first time that after peer review you take several months to finally publish the accepted and revised paper. " [Collapse]

Liguori A, Ainora ME, Di Gialleonardo L, Viceconti N, Petrucci L, Esposto G, Giustiniani MC, Mignini I, Borriello R, Galasso L, Paratore M, Garcovich M, Riccardi L, Pompili M, Grieco A, Gasbarrini A, Miele L, Zocco MA. Multiparametric ultrasound for non-invasive assessment of liver steatosis, fibrosis, and inflammation in metabolic dysfunction-associated steatotic liver disease. World J Gastroenterol 2025; 31(25): 105518

"We sincerely appreciate the professional and efficient editorial process of the World Journal of Gastroenterology. From initial ..." [Read more]

"We sincerely appreciate the professional and efficient editorial process of the World Journal of Gastroenterology. From initial submission to final publication, the entire workflow was transparent, well-organized, and timely. The reviewers provided constructive and insightful comments that significantly improved the quality of our manuscript. The editorial team was responsive and meticulous in their guidance, and the language editing was of high standard. We are grateful for the opportunity to publish in this reputable journal and look forward to future collaborations. " [Collapse]

Wang XP, Zhu JX, Liu C, Zhang HW, Sun GD, Zhai JM, Yang HJ, Liu DC. Deciphering lactate metabolism in colorectal cancer: Prognostic modeling, immune infiltration, and gene mutation insights. World J Gastroenterol 2025; 31(25): 107478

"Thank you so much for this opportunity to work with you. I am hopeful to continue this association with you in future. I would like ..." [Read more]

"Thank you so much for this opportunity to work with you. I am hopeful to continue this association with you in future. I would like to express my gratitude to the entire staff for the wonderful work they are doing. Keep doing the good work. I would like to request to reduce the time after acceptance to online publication. " [Collapse]

Parry AH, Rehaman B, Bhat SA, Wani AH, Jehangir M, Baba AA. Role of magnetic resonance defecography in the assessment of obstructed defecation syndrome. World J Radiol 2025; 17(6): 107205

18981 items Read more >>

Article Quality Tracking-Peer-Review

"Authors: Zhao JL, Wang MY, Lv YZ, Zhou YJ. Article title: Prognostic value of inflammatory markers in predicting recurrence-free ..." [Read more]

"Authors: Zhao JL, Wang MY, Lv YZ, Zhou YJ. Article title: Prognostic value of inflammatory markers in predicting recurrence-free survival in gastrointestinal stromal tumor patients: A nomogram-based approach. Their study revealed significant correlations between preoperative inflammatory markers [systemic immune-inflammation index, neutrophil/lymphocyte ratio, platelet/lymphocyte ratio (PLR) and monocyte/Lymphocyte ratio (MLR)] and recurrence-free survival in gastrointestinal stromal tumor (GIST) patients. The MLR and PLR were identified as independent risk factors for GIST recurrence. Research has highlighted the prognostic relevance of inflammatory markers in various cancers. Nomograms have been utilized in predicting survival and recurrence in different cancers. Their study pioneered the construction of a nomogram based on inflammatory markers for assessing the recurrence risk prognosis in GIST patients. The nomogram demonstrated utility in predicting GIST patient recurrence risk, emphasizing the ongoing sensitivity of inflammatory markers in patients receiving postoperative targeted therapy. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers." [Collapse]

Zhao JL, Wang MY, Lv YZ, Zhou YJ. Prognostic value of inflammatory markers in predicting recurrence-free survival in gastrointestinal stromal tumor patients: A nomogram-based approach. World J Gastrointest Oncol 2025; 17(2): 94956

"Authors: Li JD, He RQ, Dang YW, Huang ZG, Xiong DD, Zhang L, Du XF, Chen G. Article title: Unveiling expression patterns, mechanisms, ..." [Read more]

"Authors: Li JD, He RQ, Dang YW, Huang ZG, Xiong DD, Zhang L, Du XF, Chen G. Article title: Unveiling expression patterns, mechanisms, and therapeutic opportunities of transmembrane protein 106C: From pan-cancers to hepatocellular carcinoma. Herein, they conducted the study to investigate the expression implications, immune associations, and transcriptional regulatory mechanisms of transmembrane protein 106C (TMEM106C) across 34 cancer types, including liver hepatocellular carcinoma (LIHC). Their multicenter study represents the largest investigation to date of the expression pattern and biological functions of TMEM106C in LIHC. Of particular note, their study discovered the inhibitory effect of nitidine chloride on TMEM106C overexpression, which has not been reported previously. This paper is indicative for journal readers in this field." [Collapse]

Li JD, He RQ, Dang YW, Huang ZG, Xiong DD, Zhang L, Du XF, Chen G. Unveiling expression patterns, mechanisms, and therapeutic opportunities of transmembrane protein 106C: From pan-cancers to hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(2): 92437

"Authors: Gemmell JS, Lucke-Wold B. Article title: Traditional Chinese medicine and modern technology: Network pharmacology and omics ..." [Read more]

"Authors: Gemmell JS, Lucke-Wold B. Article title: Traditional Chinese medicine and modern technology: Network pharmacology and omics sequencing in gastric cancer. Gastric cancer (GC) is a heterogenous disease that incorporates the use of multiple metabolic pathways to contribute to tumorigenesis. Modern technology, which includes omics sequencing, has allowed for better characterization of these pathways and more targeted drug development by using natural components in food, nutraceuticals, to enhance treatment. However, current classification of GC as well as treatment does not address the complex nature of this disease. Omics technologies must be applied to characterize the subtypes of GC, which may lead to better application of nutraceuticals for both prevention and treatment. This letter is indicative." [Collapse]

Gemmell JS, Lucke-Wold B. Traditional Chinese medicine and modern technology: Network pharmacology and omics sequencing in gastric cancer. World J Gastrointest Oncol 2025; 17(3): 102077

"Authors: Ma YY, Wang XH, Zeng JY, Chen JB, Niu LZ. Article title: Irreversible electroporation combined with anti-programmed cell ..." [Read more]

"Authors: Ma YY, Wang XH, Zeng JY, Chen JB, Niu LZ. Article title: Irreversible electroporation combined with anti-programmed cell death protein 1 therapy promotes tumor antigen-specific CD8+ T cell response. Their study highlighted the synergistic effect of combining irreversible electroporation with anti-programmed cell death protein 1 therapy in the treatment of subcutaneous pancreatic cancer. The combination significantly enhanced T lymphocyte infiltration, elevated key cytokine levels, and promoted CD8+ T cell-mediated immune responses, resulting in a marked reduction in tumor volume. Their results suggest a promising avenue for improving immunotherapy strategies in pancreatic cancer through enhanced local tumor ablation methods. Their results are informative for journal readers in this field." [Collapse]

Ma YY, Wang XH, Zeng JY, Chen JB, Niu LZ. Irreversible electroporation combined with anti-programmed cell death protein 1 therapy promotes tumor antigen-specific CD8⁺ T cell response. World J Gastrointest Oncol 2025; 17(3): 101991

"Authors: Sapkota A, Paudel R, Pandey S, Bhatt N. Article title: Solid pseudopapillary neoplasm of the pancreas in an adolescent: ..." [Read more]

"Authors: Sapkota A, Paudel R, Pandey S, Bhatt N. Article title: Solid pseudopapillary neoplasm of the pancreas in an adolescent: A case report and review of the literature. Solid pseudopapillary neoplasm (SPN) of the pancreas is an uncommon pancreatic tumor that primarily impacts young women, especially those in their twenties and thirties. Their report highlights the case of a 15-year-old female patient who experienced a two-year history of abdominal pain and was diagnosed with a solid pseudopapillary neoplasm localized to the pancreatic tail. The patient underwent an open distal pancreatectomy accompanied by splenectomy, and histopathological examination confirmed the diagnosis of SPN. Their case underscores the possibility of SPN occurring in adolescent girls and points out the vital importance of early diagnosis and timely intervention, which can significantly enhance clinical outcomes. Although case report accompanied with some limitations for any conclusions, their report is interesting for journal readers in this field." [Collapse]

Sapkota A, Paudel R, Pandey S, Bhatt N. Solid pseudopapillary neoplasm of the pancreas in an adolescent: A case report and review of the literature. World J Gastrointest Oncol 2025; 17(3): 101859

"Authors: Geng JX, Lu YF, Zhou JN, Huang B, Qin Y. Article title: Exosome technology: A novel and effective drug delivery system ..." [Read more]

"Authors: Geng JX, Lu YF, Zhou JN, Huang B, Qin Y. Article title: Exosome technology: A novel and effective drug delivery system in the field of cancer therapy. The biocompatibility, targeting specificity, and low immunogenicity of exosomes render them as optimal carriers for drug delivery, enabling precise administration of therapeutics to diseased tissues, thereby achieving targeted treatment of cancer cells. However, the clinical application of exosome drug delivery platforms in oncology still presents challenges, necessitating further optimization to ensure their stability and efficacy. Their study focuses on elucidating the advantages of exosomes as a drug delivery platform, exploring the utilization of mesenchymal stem cell-derived exosomes in oncology therapy, and discussing their potential and future directions in cancer treatment. This letter is indicative." [Collapse]

Geng JX, Lu YF, Zhou JN, Huang B, Qin Y. Exosome technology: A novel and effective drug delivery system in the field of cancer therapy. World J Gastrointest Oncol 2025; 17(3): 101857

"Authors: Rama NJG, Sousa I. Article title: Bridging the gap: The role of technological advances in shaping gastrointestinal ..." [Read more]

"Authors: Rama NJG, Sousa I. Article title: Bridging the gap: The role of technological advances in shaping gastrointestinal oncological outcomes. Their Editorial provides a comprehensive overview of the impact of technological advances vs current state-of-the-art practices in gastrointestinal oncology, highlighting the usefulness of combining new technologies with evidence-based clinical practices to improve patient outcomes. This letter is indicative." [Collapse]

Rama NJG, Sousa I. Bridging the gap: The role of technological advances in shaping gastrointestinal oncological outcomes. World J Gastrointest Oncol 2025; 17(3): 101752

"Authors: Liu GJ, Long XY, Zhang F, Ren T, Xia X. Article title: Heterochronic gastric adenosquamous carcinoma combined with colonic ..." [Read more]

"Authors: Liu GJ, Long XY, Zhang F, Ren T, Xia X. Article title: Heterochronic gastric adenosquamous carcinoma combined with colonic adenoma: A case report. The common type of gastric cancer is adenocarcinoma, but the pathological type of gastric adenosquamous carcinoma is rare, so metachronous gastric adenosquamous carcinoma with signet ring cell carcinoma is even rarer. The metachronous tumors after esophageal cancer surgery are mostly found in the stomach, head and neck, but those occurring in the stomach and distal colon at the same time are rare. Although case report accompanied with some limitations for any conclusions, their report is interesting for journal readers in this field." [Collapse]

Liu GJ, Long XY, Zhang F, Ren T, Xia X. Heterochronic gastric adenosquamous carcinoma combined with colonic adenoma: A case report. World J Gastrointest Oncol 2025; 17(3): 101734

"Authors: Erdogan B, Usturalı Keskin FE, Özcan E, Küçükarda A, Güren AK, Köstek O, Hacioglu BM, Kodaz H. Article title: Assessment ..." [Read more]

"Authors: Erdogan B, Usturalı Keskin FE, Özcan E, Küçükarda A, Güren AK, Köstek O, Hacioglu BM, Kodaz H. Article title: Assessment of new pathological markers in early stage colon cancer: Insights and limitations. When their associations with the pathological marker in the risk group were evaluated, it was found that there was a significant correlation between the presence of poorly differentiated clusters (PDC) and the presence of PDC grade 3 and advanced T stage. Their results showed us that PDC is one of the markers to be used in cases where these risk factors are insufficient. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers." [Collapse]

Erdogan B, Usturalı Keskin FE, Özcan E, Küçükarda A, Güren AK, Köstek O, Hacioglu BM, Kodaz H. Assessment of new pathological markers in early stage colon cancer: Insights and limitations. World J Gastrointest Oncol 2025; 17(3): 101325

"Authors: Song JH, Choi SY, Kim YS, Yang SY, Han KD. Article title: Increased risk of colorectal cancer in young males with higher ..." [Read more]

"Authors: Song JH, Choi SY, Kim YS, Yang SY, Han KD. Article title: Increased risk of colorectal cancer in young males with higher cardiovascular risk: A nationwide population-based cohort study. While studies have reported an association between cardiovascular disease (CVD) and colorectal cancer (CRC), large-scale investigations on the incidence of CRC based on the risk of CVD are lacking. Their study benefits from being a nationwide population-based cohort study with long-term follow-up data spanning 10 years, which is a significant strength. Their study highlights that increased cardiovascular risk scores are significantly associated with higher CRC risk, especially among males and younger populations. Thus, males with a higher cardiovascular risk score, even at a younger age, are recommended to control their risk factors and undergo individualized CRC screening. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers." [Collapse]

Song JH, Choi SY, Kim YS, Yang SY, Han KD. Increased risk of colorectal cancer in young males with higher cardiovascular risk: A nationwide population-based cohort study. World J Gastrointest Oncol 2025; 17(3): 101260

"Authors: Bao ZC, Zhang Y, Liu ZD, Dai HJ, Ren F, Li N, Lv SY, Zhang Y. Article title: Tetrahydrocurcumin-induced apoptosis of ..." [Read more]

"Authors: Bao ZC, Zhang Y, Liu ZD, Dai HJ, Ren F, Li N, Lv SY, Zhang Y. Article title: Tetrahydrocurcumin-induced apoptosis of hepatocellular carcinoma cells involves the TP53 signaling pathway, as determined by network pharmacology. Their study investigated the molecular mechanisms by which tetrahydrocurcumin (THC), a derivative of curcumin, inhibits hepatocellular carcinoma cells. Utilizing a comprehensive approach that integrated network pharmacology, molecular docking, and in vitro experiments, the TP53 signaling pathway was identified as a critical mediator of the antitumor activity of THC. Their results are informative for journal readers in this field." [Collapse]

Bao ZC, Zhang Y, Liu ZD, Dai HJ, Ren F, Li N, Lv SY, Zhang Y. Tetrahydrocurcumin-induced apoptosis of hepatocellular carcinoma cells involves the TP53 signaling pathway, as determined by network pharmacology. World J Gastrointest Oncol 2025; 17(3): 101174

"Authors: Zhuang ZN, Zhao R, Li YX. Article title: Retrospective analysis of factors influencing the self-healing of patients with ..." [Read more]

"Authors: Zhuang ZN, Zhao R, Li YX. Article title: Retrospective analysis of factors influencing the self-healing of patients with enterocutaneous fistulas receiving conservative treatment. Enterocutaneous (EC) fistulas can cause various complications, such as infections, fluid loss, internal homeostasis imbalance, organ dysfunction, malnutrition, and other changes. Their study aimed to improve treatment outcomes for patients with EC fistulas and reduce the need for reoperation. The cure rate of patients with a single EC fistula can be effectively improved via conservative treatment combined with the use of biological fibrin glue to seal the fistula. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers." [Collapse]

Zhuang ZN, Zhao R, Li YX. Retrospective analysis of factors influencing the self-healing of patients with enterocutaneous fistulas receiving conservative treatment. World J Gastrointest Oncol 2025; 17(3): 101076

"Authors: Yuan Z, Wang JH, Cui H, Wang SY, Wei B, Cui JX. Aticle title: Mapping the landscape of gastric cancer immunotherapy: ..." [Read more]

"Authors: Yuan Z, Wang JH, Cui H, Wang SY, Wei B, Cui JX. Aticle title: Mapping the landscape of gastric cancer immunotherapy: Bibliometric insights into advances and hotspots. Their study employs bibliometric analysis to systematically elucidate the landscape of gastric cancer (GC) immunotherapy literature. Immunotherapy for GC has become a prominent research area, consistently attracting scientific scrutiny. Principal research topics include the prognostic evaluation of immunotherapy, immune microenvironment dynamics, synergistic strategies with targeted therapy, adoptive immunotherapy strategies, and the immunological treatment of gastroesophageal junction cancer. These topics continue to be at the forefront of current research initiatives. This document is indicative for journal readers in this field." [Collapse]

Yuan Z, Wang JH, Cui H, Wang SY, Wei B, Cui JX. Mapping the landscape of gastric cancer immunotherapy: Bibliometric insights into advances and hotspots. World J Gastrointest Oncol 2025; 17(3): 100997

"Authors: Li TH, Sun X, Li CG, Yin YP, Tao KX. Article title: Hypercoagulation after neoadjuvant immunochemotherapy as a new ..." [Read more]

"Authors: Li TH, Sun X, Li CG, Yin YP, Tao KX. Article title: Hypercoagulation after neoadjuvant immunochemotherapy as a new prognostic indicator in patients with locally advanced gastric cancer undergoing surgery. Their retrospective study assessed the correlation between hypercoagulation after neoadjuvant immunochemotherapy (NICT) and the prognosis of patients with locally advanced gastric cancer (LAGC). Results indicated that the non-hypercoagulation group exhibited significantly superior overall survival (OS) and disease-free survival (DFS) rates compared with the hypercoagulation group. Furthermore, multivariate analysis revealed that hypercoagulation after NICT was an independent risk factor for adverse postoperative OS and DFS. Their results suggests that hypercoagulation after NICT is an independent prognostic indicator of LAGC and may be used to evaluate therapeutic effects. Although their study design was retrospective, their results were interesting for journal readers in this field." [Collapse]

Li TH, Sun X, Li CG, Yin YP, Tao KX. Hypercoagulation after neoadjuvant immunochemotherapy as a new prognostic indicator in patients with locally advanced gastric cancer undergoing surgery. World J Gastrointest Oncol 2025; 17(3): 100927

"Authors: Hao MZ, Lin HL, Hu YB, Chen QZ, Chen ZX, Qiu LB, Lin DY, Zhang H, Zheng DC, Fang ZT, Liu JF. Article title: Combination ..." [Read more]

"Authors: Hao MZ, Lin HL, Hu YB, Chen QZ, Chen ZX, Qiu LB, Lin DY, Zhang H, Zheng DC, Fang ZT, Liu JF. Article title: Combination therapy strategy based on selective internal radiation therapy as conversion therapy for inoperable giant hepatocellular carcinoma: A case report. Although selective internal radiation therapy (SIRT) has been used to treat unresectable hepatic cancers for more than 20 years, it is mainly employed to treat patients with ≤ 8 cm tumor size. Their research reports a hepatocellular carcinoma patient with > 15 cm hepatic mass, microvascular invasion, and China Liver Cancer Staging (CNLC) IIIa who received radical hepatectomy after successful conversion therapy with SIRT using yttrium-90 resin microspheres followed by hepatic arterial infusion chemotherapy using anti-programmed death-1 antibody and tyrosine kinase inhibitor. After 4 months of SIRT, the tumor was downstaged to CNLC Ib and the future liver remnant increased from 434 mL to 802 mL. Although case report accompanied with some limitations for any conclusions, their case report is interesting for journal readers in this field." [Collapse]

Hao MZ, Lin HL, Hu YB, Chen QZ, Chen ZX, Qiu LB, Lin DY, Zhang H, Zheng DC, Fang ZT, Liu JF. Combination therapy strategy based on selective internal radiation therapy as conversion therapy for inoperable giant hepatocellular carcinoma: A case report. World J Gastrointest Oncol 2025; 17(3): 100861

"Author: Sun HT. Article title: Helicobacter pylori-related serum indicators: Cutting-edge advances to enhance the efficacy of gastric ..." [Read more]

"Author: Sun HT. Article title: Helicobacter pylori-related serum indicators: Cutting-edge advances to enhance the efficacy of gastric cancer screening. Traditional serum tumor markers exhibit low diagnostic efficacy. Although gastrin and pepsin reflect the current state of the stomach, their clinical application remains impractical. New molecular biomarkers, such as noncoding genomes, have potential utility in diagnosing and screening for gastric cancer (GC); however, further validation is required. Serum anti-Helicobacter pylori antibodies have been used in various combined examination methods for GC screening, and the relationship between specific antibodies to virulence factors and GC risk has been thoroughly researched. The application of multiple serological detection and prediction models has expanded the pool of candidate biomarkers for GC screening. This review article is well written, and is informative for journal readers in this field." [Collapse]

Sun HT. Helicobacter pylori-related serum indicators: Cutting-edge advances to enhance the efficacy of gastric cancer screening. World J Gastrointest Oncol 2025; 17(3): 100739

"Authors: Zhou J, Chen JR, Li JM, Han SQ, Deng XY, Li ZM, Tong W, Wang C, Bai Y, Zhang YM. Article title: IL-22/IL-22R1 pathway ..." [Read more]

"Authors: Zhou J, Chen JR, Li JM, Han SQ, Deng XY, Li ZM, Tong W, Wang C, Bai Y, Zhang YM. Article title: IL-22/IL-22R1 pathway enhances cholangiocarcinoma progression via ERK1/2 activation. Their research results showed that IL-22R1 is highly expressed in cholangiocarcinoma (CCA) cell lines and tissues. The binding of IL-22 to IL-22R1 forms the IL-22/IL-22R1 axis, which can promote the progression of CCA both in vivo and in vitro. The application of ERK1/2 inhibitors can reverse the promoting effect of IL-22 on CCA, providing potential therapeutic strategies for CCA’s clinical treatment. Their results are informative for journal readers in this field." [Collapse]

Zhou J, Chen JR, Li JM, Han SQ, Deng XY, Li ZM, Tong W, Wang C, Bai Y, Zhang YM. IL-22/IL-22R1 pathway enhances cholangiocarcinoma progression via ERK1/2 activation. World J Gastrointest Oncol 2025; 17(3): 102083

"Authors: Kotelevets SM, Chukov SZ. Article title: Gastric cancer diagnosis and prevention: Detecting precancerous at community ..." [Read more]

"Authors: Kotelevets SM, Chukov SZ. Article title: Gastric cancer diagnosis and prevention: Detecting precancerous at community level. They present a consistent system of population-based serological screening for precancerous diseases and changes in the gastric mucosa as a first-line screening strategy. The use of modern endoscopic and morphological diagnostic methods to verify pre-cancerous pathology of the stomach is recommended as a second line of screening for precancerous condition of the stomach. A detailed description of the markers of these pathological changes is given in the manuscript. Recent advances in research to identify the risk factors for stomach cancer have made it possible to use specific science to predict this deadly disease. This letter is indicative." [Collapse]

Kotelevets SM, Chukov SZ. Gastric cancer diagnosis and prevention: Detecting precancerous at community level. World J Gastrointest Oncol 2025; 17(3): 100521

"Authors: Liu Y, Li XF. Articlew title: Characteristics and therapeutic strategies for familial gastrointestinal stromal tumors. The ..." [Read more]

"Authors: Liu Y, Li XF. Articlew title: Characteristics and therapeutic strategies for familial gastrointestinal stromal tumors. The management of familial gastrointestinal stromal tumors (GISTs) depends on the conduct of genetic surveillance, with early screening for first-degree relatives being essential. Current treatment strategies are essentially the same as those used for sporadic GISTs, primarily consisting of surgery and tyrosine kinase inhibitor targeted therapy. For familial GISTs, additional experience and evidence are required for treatment, prognosis, and monitoring; therefore, it is advisable to adopt more proactive therapeutic and follow-up strategies. This letter is indicative." [Collapse]

Liu Y, Li XF. Characteristics and therapeutic strategies for familial gastrointestinal stromal tumors. World J Gastrointest Oncol 2025; 17(3): 100463

"Author: Sukocheva OA. Article title: Resveratrol and pancreatic cancers: Questions and future perspectives. A promising new ..." [Read more]

"Author: Sukocheva OA. Article title: Resveratrol and pancreatic cancers: Questions and future perspectives. A promising new direction for the treatment of pancreatic cancer has been investigated and reported by Jiang et al. Using immunohistochemistry, the authors assessed pancreatic cancer tissues and detected the presence of senescent cancer-associated fibroblasts (CAFs) in the tumor microenvironment. Following this, they observed the ability of the natural polyphenolic compound resveratrol to reverse the senescent CAF phenotype and inhibit pancreatic cancer progression in vitro and in vivo. This editorial assesses important aspects of the original article and discusses future perspectives of resveratrol-containing therapy. This letter is indicative." [Collapse]

Sukocheva OA. Resveratrol and pancreatic cancers: Questions and future perspectives. World J Gastrointest Oncol 2025; 17(3): 100342

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Peer-Reviewers and Manuscript Statistics

Editorial board members: 2266

Peer-reviewers: 32188

Manuscripts received today: 5

Manuscript reviews today: 12

Unhandled manuscripts today: 157

Active peer-reviewers today: 611

Reviewer acceptance today: 13

Reviewer refusals today: 14

Total accepted manuscripts: 36764

Total rejected manuscripts: 42272

Total peer-reviewers: 4279992

Total submissions: 34910