Baishideng Publishing Group

Wang S, Liu HR, Zou KT, Gao F, Wang SY, Mutasa B, Li J, Hong P. Ulnar lengthening in the treatment of forearm deformity caused by hereditary multiple exostoses in children. World J Orthop 2025; 16(7): 108319

"We are very satisfied with the publication process of our manuscript in the World Journal of Orthopedics. The peer reviewers provided ..." [Read more]

"We are very satisfied with the publication process of our manuscript in the World Journal of Orthopedics. The peer reviewers provided highly professional and constructive feedback, which significantly improved the quality of our article. The editorial team was exceptionally responsive and efficient, ensuring smooth communication and a rapid review timeline. From submission to publication, the process was well-organized and transparent, demonstrating the journal’s commitment to supporting authors. We sincerely appreciate the editors’ dedication and the reviewers’ expertise, which have greatly contributed to the final outcome. This experience reinforces our confidence in the journal’s credibility and academic standards. " [Collapse]

Pu FF, Peng XL, Zhou FZ, Zhao XL, Yang L, Cao JQ, Wei L, Feng J, Xia P. Treatment of lumbar tuberculosis with minimally invasive anterior lesion clearance combined with posterior fixation. World J Orthop 2025; 16(7): 106041

"I am very pleased with the overall publication process. The editorial team was professional and efficient throughout. The peer review ..." [Read more]

"I am very pleased with the overall publication process. The editorial team was professional and efficient throughout. The peer review was fair, constructive, and helped enhance the quality of my work. Communication was clear and timely, and I appreciated the smooth workflow from submission to publication. Thank you for the positive experience. " [Collapse]

Yousif Mohamed AM, Salih M, Mohamed M, Abbas AE, Elsiddig M, Osama Omar M, Abdelsalam M, Elhag B, Mohamed N, Eisa Ahmed SH, Ahmed S, Mohamed D, Omar D. Comparative efficacy of cementless bipolar hemiarthroplasty and proximal femoral nail anti-rotation in unstable intertrochanteric fractures: A meta-analysis. World J Orthop 2025; 16(7): 107950

"It was a great pleasure to work with the journal’s editing team. The peer review process was very fast. However, the time given for ..." [Read more]

"It was a great pleasure to work with the journal’s editing team. The peer review process was very fast. However, the time given for revision is somewhat short. Sometimes it is very difficult to do corrections in revised manuscript for 14 days. The authors use to be very busy performing operations and doing other practical work " [Collapse]

Shastov AL, Kolchin SN, Malkova TA. Effectiveness of the induced membrane technique in aseptic and infected long-bone defect management: Are there any differences? World J Orthop 2025; 16(7): 107337

"The review process of the World Journal of Diabetes is highly efficient. Peer review is initiated just three days after submission, ..." [Read more]

"The review process of the World Journal of Diabetes is highly efficient. Peer review is initiated just three days after submission, and ultimately five experts agree to participate in the review process. Following the revision stage, a second editorial decision is made promptly. Throughout the subsequent publication process, communication with the journal editor is smooth and effective, resulting in a successful and satisfactory publication experience. " [Collapse]

Xiang LL, Feng J, Li SY, Zhu YT, Chen YJ, Zhong TY, Zhu YF, Zeng Y. Predictive ability of lipid indices for large-for-gestational-age infants in pregnant females with gestational diabetes mellitus. World J Diabetes 2025; 16(7): 104306

"The overall process of processing an article, right from submission to publication of an article, is very appreciable. The team at ..." [Read more]

"The overall process of processing an article, right from submission to publication of an article, is very appreciable. The team at the World Journal of Diabetes is very particular about the processing of manuscript at each and every step and is very cooperative. The overall process is very satisfactory. I heartily congratulate the team for their positive efforts and wish them all the best. " [Collapse]

Nagoba BS, Gavkare AM, Nanaware N, Mumbre SS, Bhavthankar S. Systemic immune indicators: Early predictors of renal damage in children with newly diagnosed type 1 diabetes mellitus. World J Diabetes 2025; 16(7): 108209

"I am generally satisfied with the editing and publishing process of the article. For a non-native English speaker, it is necessary ..." [Read more]

"I am generally satisfied with the editing and publishing process of the article. For a non-native English speaker, it is necessary to polish the language of the article. However, I don't understand if it is necessary to have the article edited and polished twice as required. Throughout the submission process, it is very important to have effective communication with the editorial department, but the communication channels seem not to be very convenient. " [Collapse]

Yang YS, Li XR, Wang ZM, Zheng L, Li JL, Cui XL, Song YB, Ma JJ, Guo HF, Gao LX, Zhou XH. Effect of rapamycin nanoparticles in an animal model of primary biliary cholangitis. World J Hepatol 2025; 17(6): 104073

"The overall experience with the journal was very satisfactory. The submission system was user-friendly, and the editorial team provided ..." [Read more]

"The overall experience with the journal was very satisfactory. The submission system was user-friendly, and the editorial team provided timely updates throughout the process. The peer review comments were constructive, fair, and significantly improved the quality of our manuscript. We also appreciated the high-quality editing, layout, and publication efficiency. We look forward to submitting future work to this journal. " [Collapse]

Lv Y, Li WX, Sun L, Xin LP, Li T, Zhong WT, Zhu HY, An R, Liu AJ, Chen L. Neutrophil extracellular traps predict sensitivity to neoadjuvant chemotherapy combined with immunotherapy in locally advanced gastric cancer. World J Gastrointest Oncol 2025; 17(7): 105723

"This submission experience was truly impressive. From the efficient initial review to the rigorous peer-review process, and finally ..." [Read more]

"This submission experience was truly impressive. From the efficient initial review to the rigorous peer-review process, and finally the swift online publication, every step demonstrated the journal's high level of professionalism. The editorial team maintained smooth communication, and the reviewers' feedback was highly constructive, significantly contributing to the improvement of the paper's quality. " [Collapse]

Gao L, Liu ZX, Wang JN. Predictive model and risk analysis for outcomes in diabetic foot ulcer using eXtreme Gradient Boosting algorithm and SHapley Additive exPlanation. World J Diabetes 2025; 16(7): 104789

"Overall, our experience with the publication process in World Journal of Diabetes has been highly satisfactory. From the initial ..." [Read more]

"Overall, our experience with the publication process in World Journal of Diabetes has been highly satisfactory. From the initial submission to the online publication, the editorial team demonstrated professionalism, efficiency, and clear communication throughout each stage. The peer review process was rigorous yet constructive，feedback from reviewers was timely, detailed, and significantly helped improve the quality of our manuscript. We particularly appreciated the prompt responses from the editorial assistants, who addressed our questions and revisions with patience, ensuring a smooth and transparent workflow. " [Collapse]

Zhao JD, Guo MZ, Zhang Y, Zhu SH, Wang YT, Zhang YP, Liu X, Cheng S, Wang F, Xu Q, Ruan NB, Fang ZH. Efficacy of Xiaokeqing granules and lifestyle intervention in treating prediabetes mellitus considering metabolomic biomarkers: A randomised controlled trial. World J Diabetes 2025; 16(7): 105219

"We are highly satisfied with the overall editorial and publishing experience with the journal. The online submission system was ..." [Read more]

"We are highly satisfied with the overall editorial and publishing experience with the journal. The online submission system was intuitive and efficient, and the peer review process was conducted in a timely, fair, and constructive manner. The reviewers’ comments were both professional and insightful, significantly contributing to the improvement of our manuscript. The editorial team demonstrated excellent attention to detail during the editing and typesetting stages. The quality of the article PDFs, online full-text layout, figures, and tables met our expectations, and the final published version was accurate and well-presented. We also appreciate the journal’s adherence to academic norms and ethical standards, including clear publication policies and a transparent academic misconduct screening process. In summary, the publication process was smooth, rigorous, and author-friendly. We thank the editorial office, reviewers, and production team for their dedicated support and professional service. " [Collapse]

Luo C, Yu XM, Zeng MQ, Duan CZ, Xu SY, Zhu CY, Zheng ZG, Sun D, Fang J, He DJ. Breaking the diabetes-depression cycle: Exploring shared mechanisms, neuroinflammation, and emerging interventions for metabolic-mood comorbidities. World J Diabetes 2025; 16(7): 107406

"During the repair process, the editor insisted that the final results should be presented in the form of a PPT. This requirement was ..." [Read more]

"During the repair process, the editor insisted that the final results should be presented in the form of a PPT. This requirement was extremely unreasonable. Other editable versions of the image, such as the AI format, should be allowed. Editors should assist authors in completing the revision and publication of their articles more efficiently, rather than adding unnecessary tasks to the authors. " [Collapse]

Cao X, Zheng SH, Shen JM, Li SZ, Hou L, Zhang JX, Li XK, Du HB, Zhang LP, Ye YA, Zao XB. Pan-cancer analysis of UDP-glucose 6-dehydrogenase in human tumors and its function in hepatocellular carcinoma. World J Gastrointest Oncol 2025; 17(7): 105981

"The online submission system was user-friendly, allowing for efficient manuscript uploading and tracking. The peer review process ..." [Read more]

"The online submission system was user-friendly, allowing for efficient manuscript uploading and tracking. The peer review process was transparent and rigorous, with constructive feedback provided in a timely manner. The journal’s editorial team maintained clear communication throughout, ensuring a smooth submission experience. Overall, the combination of a robust review process and supportive editorial workflow is highly commendable. " [Collapse]

Wang Z, Shi FC, Hou SB, Sun QQ, Fang CY. Association of dietary index for gut microbiota and all-cause and cardiovascular mortality in patients with diabetes or prediabetes. World J Diabetes 2025; 16(7): 107111

"This is one of my best ever published work and the whole process of publication has been great except for slight delays in the peer ..." [Read more]

"This is one of my best ever published work and the whole process of publication has been great except for slight delays in the peer reviews and the time from submission to publication. The journal should consider an online e-pub option as soon as the paper is accepted to avoid delays in online repository of the articles as delays may result in publication of similar papers prior to the publication of the WJD paper. I wish all the best to the Journal. " [Collapse]

Gagnon CA, Buchanan K, Deaver JM, Schmitt JA, Lahart IM, Shetty S, Ashraf AP, Pappachan JM. Pharmacological management of type 2 diabetes mellitus in children and adolescents: A systematic review and network meta-analysis. World J Diabetes 2025; 16(7): 106890

"The time interval between the first decision letter after the paper submission and the time it took to receive the final result after ..." [Read more]

"The time interval between the first decision letter after the paper submission and the time it took to receive the final result after the re-review was relatively fast. I think the evaluations of the three reviewers were appropriate and fair. The paper revision process based on the reviewers' comments was very helpful in improving the quality of the paper. I would like to submit another paper that fits the scope of this journal in the future. " [Collapse]

Bae EH, Lim SY, Kim BS, Han KD, Suh SH, Choi HS, Kim CS, Ma SK, Kim SW. Exercise intensity and the risk of end-stage renal disease in diabetes: A nationwide population-based study. World J Diabetes 2025; 16(7): 108344

"The evaluations by the reviewers were fair and reliable, and the revision of the paper based on the evaluation comments was very ..." [Read more]

"The evaluations by the reviewers were fair and reliable, and the revision of the paper based on the evaluation comments was very helpful in improving the quality of the paper. We were satisfied that the entire process, from paper submission to peer review, revision, re-examination, and publication, was conducted fairly and quickly, and that they actively worked to enable the publication of high-quality papers. It is expected that this will lead to a leap forward as a better journal. " [Collapse]

Choi HS, Kim B, Han KD, Suh SH, Kim CS, Bae EH, Ma SK, Kim SW. Impact of longer diabetes duration and lower estimated glomerular filtration rate on cardiovascular complications and mortality: A nationwide population-based study. World J Diabetes 2025; 16(7): 107647

"The submission process was found to be highly satisfactory. From the preliminary evaluation to the subsequent peer review, ..." [Read more]

"The submission process was found to be highly satisfactory. From the preliminary evaluation to the subsequent peer review, modifications, and ultimate approval, each phase of the procedure was meticulously rigorous. The reviewers' comments were instrumental in enhancing the quality of the manuscript. The editorial team demonstrated commendable responsibility, addressing issues in a timely manner and providing comprehensive feedback. In conclusion, the present submission process has proven to be highly satisfactory. " [Collapse]

Zuo DB, Wang CH, Sang M, Sun XD, Chen GP, Ji KK. Stem cell therapy for diabetes: Advances, prospects, and challenges. World J Diabetes 2025; 16(7): 107344

"This journal features rapid review and efficient editorial processing, making it ideal for publication. The editors are friendly and ..." [Read more]

"This journal features rapid review and efficient editorial processing, making it ideal for publication. The editors are friendly and always respond promptly to correspondence. The reviewers raised highly professional and pertinent questions, pinpointing key issues effectively. The reviewers raised highly professional and pertinent questions, pinpointing key issues effectively. We sincerely appreciate all the experts for their dedicated efforts and valuable contributions. " [Collapse]

Pu WF, Yang X, Wang XQ, Guo XG, Yang MY. Stemness signatures reflect prognostic disturbances in gastric cancer. World J Gastrointest Oncol 2025; 17(7): 107211

"We sincerely appreciate the substantial assistance from the reviewers and editors for this paper. Having undergone three rounds of ..." [Read more]

"We sincerely appreciate the substantial assistance from the reviewers and editors for this paper. Having undergone three rounds of review, the quality of the manuscript has been significantly improved with each revision. WJD is a truly excellent journal that strikes a balance between academic rigor and accessibility for authors. We look forward to the opportunity to submit future work to WJD again. " [Collapse]

Yang TS, Du M, Luo LY, Lin L, Luo XL. Extra-renal role of urate transporter-1 in diabetes. World J Diabetes 2025; 16(7): 107673

19036 items Read more >>

Article Quality Tracking-Peer-Review

"Only three articles examined are very few, the search should be expanded. also missing the PROSPERO membership number and the PRISMA ..." [Read more]

"Only three articles examined are very few, the search should be expanded. also missing the PROSPERO membership number and the PRISMA check-list. More detailed information on research should be provided to make it more rigorous. It would also be useful to specify the limitations of the study and what can be done in future studies to improve these limits Finally , a English editing is needed." [Collapse]

"Survival rates following radical surgery for gastric neuroendocrine neoplasms (g-NENs) are low, with high recurrence rates. Liu, et ..." [Read more]

"Survival rates following radical surgery for gastric neuroendocrine neoplasms (g-NENs) are low, with high recurrence rates. Liu, et al’s study addressed a critical issue in determining the postoperative prognosis of gastric neuroendocrine tumors by identifying the significance of lymph node ratio. Moreover, the random survival forest model, a machine-learning approach, surpasses traditional Cox proportional hazards models by enhancing predictive accuracy, clinical utility, and overall performance. This model’s ability to stratify patient risks and personalize survival predictions can aid in formulating targeted postoperative strategies, thus realizing an important aspect of personalized “precision medicine”. This paper is indicative for journal readers in this field." [Collapse]

Wang HN, An JH, Zong L. Estimating prognosis of gastric neuroendocrine neoplasms using machine learning: A step towards precision medicine. World J Gastrointest Oncol 2024; 16(12): 4548-4552

"Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths due to late diagnosis and high recurrence rates. ..." [Read more]

"Hepatocellular carcinoma (HCC) is one of the leading causes of cancer-related deaths due to late diagnosis and high recurrence rates. Key biomarkers such as enhancer of zeste homolog 2 and fatty acid binding protein 5, along with other genetic biomarkers provide insights into HCC progression and potential therapeutic targets. This paper is indicative for journal readers in this field. " [Collapse]

Shodry S, Hasan YTN, Ahdi IR, Ulhaq ZS. Gene targets with therapeutic potential in hepatocellular carcinoma. World J Gastrointest Oncol 2024; 16(12): 4543-4547

"In this Editorial we comment on the interesting article by Liu, et al. The controlling nutritional status (CONUT) score was ..." [Read more]

"In this Editorial we comment on the interesting article by Liu, et al. The controlling nutritional status (CONUT) score was significantly associated with the prognosis of colorectal cancer patients, as supported by a large body of literature. Compared with other nutritional scores, the CONUT score might be introduced in clinical practice as an optimal prognostic nutritional index to predict patient outcome." [Collapse]

Berardi R, Chiariotti R, Mentrasti G. Is nutritional status a new indicator to use in clinical practice for colorectal cancer patients? World J Gastrointest Oncol 2024; 16(12): 4537-4542

"In this Editorial, they highlighted potential pitfalls in the current classification of mixed neuroendocrine non-neuroendocrine ..." [Read more]

"In this Editorial, they highlighted potential pitfalls in the current classification of mixed neuroendocrine non-neuroendocrine neoplasms and commented on challenges in the management of this heterogeneous group of malignancies in light of the paucity of evidence in the field. Improved biological and clinical knowledge were needed to generate robust classification schemes that will in turn provide clarity on the epidemiology of the disease, prognosis of affected patients and guidance for treatment tailoring. This paper is indicative for journal readers in this field." [Collapse]

Cives M, Porta C, Palmirotta R. Mixed neuroendocrine non-neuroendocrine tumors: The quest for evidence. World J Gastrointest Oncol 2024; 16(12): 4532-4536

"Gastric cancer remains a formidable global health concern with significant morbidity and mortality rates, despite the fact that ..." [Read more]

"Gastric cancer remains a formidable global health concern with significant morbidity and mortality rates, despite the fact that numerous advances have been made to improve conventional therapies. This Editorial article integrated network pharmacology insights with rigorous experimental validation to highlight the potential of Xiaojianzhong decoction as a multifaceted therapeutic approach for gastric cancer. This paper is indicative for journal readers in this field." [Collapse]

Cheng CH, Hao WR, Cheng TH. Exploring Xiaojianzhong decoction's potential in gastric cancer treatment: Integrative insights and experimental validation. World J Gastrointest Oncol 2024; 16(12): 4553-4558

"Mixed neuroendocrine non-neuroendocrine neoplasms constitute rare tumors that are located mainly in the gastrointestinal tract and ..." [Read more]

"Mixed neuroendocrine non-neuroendocrine neoplasms constitute rare tumors that are located mainly in the gastrointestinal tract and have high degrees of malignancy, and the frequency of these tumors has been increasing. The rare but steadily increasing number of gastrointestinal mixed neuroendocrine non-neuroendocrine neoplasms and pure neuroendocrine carcinomas require more radical treatment than slow-growing neuroendocrine neoplasms do and they are related to poor prognosis. They constitute a complicated diagnostic and therapeutic challenge. The current management strategy begins with surgery and is followed by chemotherapy. New chemotherapeutics and novel biological agents for targeted therapy, along with immunotherapy broaden the range of therapeutic options, providing promising outcomes. Effective management should be individualized and multidisciplinary. This paper is indicative for journal readers in this field." [Collapse]

Pavlidis ET, Galanis IN, Pavlidis TE. Critical considerations for the management of gastrointestinal mixed neuroendocrine non-neuroendocrine neoplasms and pure neuroendocrine carcinomas. World J Gastrointest Oncol 2024; 16(12): 4559-4564

"Within the intricate milieu of colorectal cancer (CRC) tissues, cancer-associated fibroblasts (CAFs) act as pivotal orchestrators, ..." [Read more]

"Within the intricate milieu of colorectal cancer (CRC) tissues, cancer-associated fibroblasts (CAFs) act as pivotal orchestrators, wielding considerable influence over tumor progression. Their review endeavored to dissect the multifaceted functions of CAFs within the realm of CRC, thereby highlighting their indispensability in fostering CRC malignant microenvironment and indicating the development of CAFs-targeted therapeutic interventions. Through a comprehensive synthesis of current knowledge, their review delineated insights into CAFs-mediated modulation of cancer cell proliferation, invasiveness, immune evasion, and neovascularization, elucidating the intricate web of interactions that sustain the pro-tumor metabolism and secretion of multiple factors. Additionally, recognizing the high level of heterogeneity within CAFs is crucial, as they encompass a range of subtypes, including myofibroblastic CAFs, inflammatory CAFs, antigen-presenting CAFs, and vessel-associated CAFs. Innovatively, the symbiotic relationship between CAFs and the intestinal microbiota is explored, shedding light on a novel dimension of CRC pathogenesis. Despite remarkable progress, the orchestrated dynamic functions of CAFs remain incompletely deciphered, underscoring the need for continued research endeavors for therapeutic advancements in CRC management. This review article is well written, and is informative for journal readers in this field." [Collapse]

Cui JY, Ma J, Gao XX, Sheng ZM, Pan ZX, Shi LH, Zhang BG. Unraveling the role of cancer-associated fibroblasts in colorectal cancer. World J Gastrointest Oncol 2024; 16(12): 4565-4578

"In their report, they assessed the prognostic value of gamma-glutamyl transpeptidase to platelet ratio (GPR) in early hepatitis B ..." [Read more]

"In their report, they assessed the prognostic value of gamma-glutamyl transpeptidase to platelet ratio (GPR) in early hepatitis B virus (HBV)-related hepatocellular carcinoma (HCC) patients. They evaluated the clinical utility of preoperative GPR in predicting outcomes for solitary HBV-related HCC patients using propensity score matching, restricted cubic spline, survival analyses and stratified analyses. Preoperative GPR levels facilitated recurrence monitoring and inform treatment strategies, potentially enhancing the quality of life for HCC patients. Although case report accompanied with some limitations for any conclusions, their report is interesting for journal readers in this field." [Collapse]

Yang CK, Wei ZL, Shen XQ, Jia YX, Wu QY, Wei YG, Su H, Qin W, Liao XW, Zhu GZ, Peng T. Prognostic utility of gamma-glutamyl transpeptidase to platelet ratio in patients with solitary hepatitis B virus-related hepatocellular carcinoma after hepatectomy. World J Gastrointest Oncol 2024; 16(12): 4579-4596

"Their developed and validated a promising machine learning architecture for predicting the 3-category survival times (cutoff values ..." [Read more]

"Their developed and validated a promising machine learning architecture for predicting the 3-category survival times (cutoff values of 3 years and 5 years) for four survival times (overall, disease-free, recurrence-free, and distant metastasis-free survival) and screened corresponding important variables. Fivefold cross validation and bootstrap validation were conducted. The models were evaluated with the area under the curve (AUC); moreover, the effectiveness of our variable screening methods was evaluated by comparing the models’ pre- and post-screening AUCs. SHapley Additive exPlanations were used to explain the decision-making process. Nomograms were drawn for various applications. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers in this field." [Collapse]

Ji XL, Xu S, Li XY, Xu JH, Han RS, Guo YJ, Duan LP, Tian ZB. Prognostic prediction models for postoperative patients with stage I to III colorectal cancer based on machine learning. World J Gastrointest Oncol 2024; 16(12): 4597-4613

"Their retrospective study explores the safety, efficacy, and long-term prognosis of local excision (LE) in patients with middle-low ..." [Read more]

"Their retrospective study explores the safety, efficacy, and long-term prognosis of local excision (LE) in patients with middle-low rectal cancer who responded well to neoadjuvant chemoradiotherapy. Their results demonstrated that LE can achieve high rates of organ preservation and favorable oncological outcomes, including a 5-year disease-free survival rate of 88.4% and overall survival rate of 92.9%. Complications were manageable and non-severe. Their study supported the potential of minimally invasive treatments in selected patients, highlighting the importance of patient participation in treatment decisions. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers in this field." [Collapse]

Chen N, Li CL, Wang L, Yao YF, Peng YF, Zhan TC, Zhao J, Wu AW. Local excision for middle-low rectal cancer after neoadjuvant chemoradiation: A retrospective study from a single tertiary center. World J Gastrointest Oncol 2024; 16(12): 4614-4624

"Their retrospective analyses spanned a decade (January 1, 2012 to September 30, 2022) and included 5417 patients from Beijing Youan ..." [Read more]

"Their retrospective analyses spanned a decade (January 1, 2012 to September 30, 2022) and included 5417 patients from Beijing Youan Hospital, Capital Medical University. Using Cox regression and competing risk regression models, they identified several key factors that significantly contributed to the risk of hepatocellular carcinoma in patients with cirrhosis. Specifically, their study underscored the increased association of hepatitis B cirrhosis with hepatocellular carcinoma incidence and highlights other significant risk factors, including male sex, advanced age, viral hepatitis-related cirrhosis, elevated blood ammonia, and lower albumin and platelet levels. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers in this field." [Collapse]

Zhou DQ, Liu JY, Zhao F, Zhang J, Liu LL, Jia JR, Cao ZH. Risk factors for hepatocellular carcinoma in cirrhosis: A comprehensive analysis from a decade-long study. World J Gastrointest Oncol 2024; 16(12): 4625-4635

"The Esophageal cancer (EC) often occurs in the elderly, with approximately 33% of patients aged ≥ 75 years at the time of diagnosis. ..." [Read more]

"The Esophageal cancer (EC) often occurs in the elderly, with approximately 33% of patients aged ≥ 75 years at the time of diagnosis. Since patients aged 75 years and above are often excluded from many clinical trials of EC, there is a lack of agreement regarding the prognosis and treatment of this population. They retrospectively analyzed the clinical characteristics, toxic reactions, and survival information of elderly patients with EC aged ≥ 75 years who received intensity-modulated radiotherapy. Their analyses aimed to evaluate the prognostic factors affecting overall survival. They found that the Charlson comorbidity index and nutritional risk screening 2002 were independent prognostic factors for overall survival. Their results suggested that when formulating treatment plans for elderly patients with EC, full attention should be given to age-related biological indicators such as comorbidities and nutrition. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers in this field." [Collapse]

Hu LL, Rong F, Liu L, Zhang L, Zhang LL, Yang Q, Xia ZL, Wang H. Prognosis of radiotherapy for esophageal cancer in elderly patients exceeding seventy-five years old. World J Gastrointest Oncol 2024; 16(12): 4636-4649

"The γ-glutamyl transferase to albumin ratio has been confirmed for the first time to be predictive in hepatocellular carcinoma ..." [Read more]

"The γ-glutamyl transferase to albumin ratio has been confirmed for the first time to be predictive in hepatocellular carcinoma undergoing transarterial chemoembolization and transarterial chemoembolization combined with systemic therapy in this large-sample multicenter study. A nomogram model for predicting postoperative survival was also established based on γ-glutamyl transferase to albumin ratio, which was empirically demonstrated to have strong predictive ability. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers in this field." [Collapse]

Wu ZY, Li H, Chen JL, Su K, Weng ML, Han YW. Nomogram model based on γ-glutamyl transferase to albumin ratio predicts survival in hepatocellular carcinoma patients with transarterial chemoembolization treatment. World J Gastrointest Oncol 2024; 16(12): 4650-4662

"The deep learning model (DLM) was validated to accurately predict the risk classification of gastrointestinal stromal tumors. The ..." [Read more]

"The deep learning model (DLM) was validated to accurately predict the risk classification of gastrointestinal stromal tumors. The combined DLM outperformed DLM in predicting risk stratification. The combined model has potential to guide and facilitate clinical decision-making. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers in this field." [Collapse]

Li Y, Liu YB, Li XB, Cui XN, Meng DH, Yuan CC, Ye ZX. Deep learning model combined with computed tomography features to preoperatively predicting the risk stratification of gastrointestinal stromal tumors. World J Gastrointest Oncol 2024; 16(12): 4663-4674

"In their study, patients diagnosed with advanced gastroenteropancreatic neuroendocrine tumors who were treated with the temozolomide ..." [Read more]

"In their study, patients diagnosed with advanced gastroenteropancreatic neuroendocrine tumors who were treated with the temozolomide and capecitabine regimen exhibited a median overall survival of 49 months, with 42% surviving at 60 months. The regimen was well-tolerated, and most patients experienced stable disease. Their results suggested that this treatment could be viable in settings where standard therapies are unavailable or inaccessible, although further prospective studies were needed for confirmation. Although their study design accompanied with some limitations for any conclusions, their results were informative for journal readers in this field." [Collapse]

Cruz-Diaz WE, Paitan V, Medina J, Flores R, Haro-Varas J, Mantilla R, Castro-Oliden V. Temozolomide and capecitabine regimen as first-line treatment in advanced gastroenteropancreatic neuroendocrine tumors at a Latin American reference center. World J Gastrointest Oncol 2024; 16(12): 4675-4684

"Supplementation with 1,25-dihydroxy-vitamin D [1,25(OH)2D3] improved hepatic steatosis and lipid metabolism in nonalcoholic fatty ..." [Read more]

"Supplementation with 1,25-dihydroxy-vitamin D [1,25(OH)2D3] improved hepatic steatosis and lipid metabolism in nonalcoholic fatty liver disease, linked to its capacity to reverse the proinflammatory M1 polarization of hepatic macrophages, partially by regulating the vitamin D receptor-peroxisome proliferator activated receptor γ pathway. The involvement of 1,25(OH)2D3 in inhibiting fatty-acid-induced proinflammatory M1 polarization of macrophages played a direct role in relieving lipid accumulation and metabolism in hepatocytes. Their results are informative for journal readers in this field." [Collapse]

Luo WJ, Dong XW, Ye H, Zhao QS, Zhang QB, Guo WY, Liu HW, Xu F. Vitamin D 1,25-Dihydroxyvitamin D₃ reduces lipid accumulation in hepatocytes by inhibiting M1 macrophage polarization. World J Gastrointest Oncol 2024; 16(12): 4685-4699

"Despite advances in therapy for colorectal cancer (CRC), the 5-year survival rate for CRC patients in China remains only 56.9%. Their ..." [Read more]

"Despite advances in therapy for colorectal cancer (CRC), the 5-year survival rate for CRC patients in China remains only 56.9%. Their study explored the effects of matrine on CRC by targeting a newly identified anti-apoptotic protein, Shank-associated RH domain interactor (SHARPIN). SHARPIN was discovered through proteomic analysis and its expression was validated in both the TCGA database and our patient cohort using immunohistochemistry. Inhibiting SHARPIN expression led to increased apoptosis and reduced proliferation, invasion, and migration of CRC cells in vitro. Matrine's ability to inhibit SHARPIN and induce apoptosis highlights its potential as a promising therapeutic agent for CRC. Their results are informative for journal readers in this field." [Collapse]

Zhou YC, Wang QQ, Zhou GYJ, Yin TF, Zhao DY, Sun XZ, Tan C, Zhou L, Yao SK. Matrine promotes colorectal cancer apoptosis by downregulating shank-associated RH domain interactor expression. World J Gastrointest Oncol 2024; 16(12): 4700-4715

"Their study highlighted spermine synthase (SMS) as a pivotal molecule regulating DNA damage and autophagy in cancer cells. SMS promoted ..." [Read more]

"Their study highlighted spermine synthase (SMS) as a pivotal molecule regulating DNA damage and autophagy in cancer cells. SMS promoted DNA repair and activated the mammalian target of rapamycin signaling pathway, resulting in the inhibition of cellular autophagy. Collectively, SMS emerges as a promising therapeutic target to enhance colorectal cancer radiosensitivity, providing novel insights into the development of colorectal cancer treatment strategies. Their results are informative for journal readers in this field." [Collapse]

Guo YB, Wu YM, Lin ZZ. Enhancing the radiosensitivity of colorectal cancer cells by reducing spermine synthase through promoting autophagy and DNA damage. World J Gastrointest Oncol 2024; 16(12): 4716-4727

"Their study systematically evaluated the efficacy and safety of transhepatic arterial chemoembolization with drug-loaded microspheres ..." [Read more]

"Their study systematically evaluated the efficacy and safety of transhepatic arterial chemoembolization with drug-loaded microspheres in the treatment of unresectable primary liver cancer. Through a meta-analysis of relevant literature, the effect of this treatment in prolonging survival, relieving symptoms and improving quality of life of patients was discussed, and the incidence of adverse reactions and complications was evaluated, so as to provide more scientific treatment recommendations for clinicians. Their results are interesting." [Collapse]

Deng J, Mi YH, Xie L, Sun XX, Liu DH, Long HJ, He LY, Wu DH, Shang HC. Efficacy and safety of transhepatic arterial chemoembolization with drug-loaded microspheres in unresectable primary liver cancer. World J Gastrointest Oncol 2024; 16(12): 4728-4737

15687 items Read more >>

Peer-Reviewers and Manuscript Statistics

Editorial board members: 2265

Peer-reviewers: 32365

Manuscripts received today: 12

Manuscript reviews today: 30

Unhandled manuscripts today: 130

Active peer-reviewers today: 1705

Reviewer acceptance today: 65

Reviewer refusals today: 71

Total accepted manuscripts: 36896

Total rejected manuscripts: 42380

Total peer-reviewers: 4290569

Total submissions: 35011