Preoperative perineural invasion in rectal cancer based on deep learning radiomics stacking nomogram: A retrospective study

Table 1 Statistical analysis results of clinical characteristics, n (%)

Characteristics	Training set (n = 242)		P value	Test set (n = 61)		P value
	PNI (n = 148)	PNI+ (n = 94)		PNI (n = 40)	PNI+ (n = 21)
Age, (mean ± SD) (years)	67.01 ± 10.57	64.26 ± 12.06	0.063	67.33 ± 8.18	63.104 ± 8.66	0.065
Gender			0.248			0.86
Male	85 (58.2)	54 (39.1)		20 (64.5)	11 (35.5)
Female	63 (65.6)	33 (34.4)		20 (66.7)	10 (33.3)
Smoking			0.882			0.396
No	101 (60.8)	65 (39.2)		29 (69.0)	13 (31.0)
Yes	47 (51.8)	29 (38.2)		11 (57.9)	8 (42.1)
HGB (g/L)	126.98 ± 20.67	130.69 ± 20.00	0.071	128.881 ± 14.16	128.67 ± 22.28	0.965
RBC (1012/L)	4.28 ± 0.62	4.40 ± 0.44	0.126	4.40 ± 0.47	4.28 ± 0.48	0.339
WBC (109/L)	6.55 ± 1.79	6.84 ± 2.19	0.265	6.18 ± 1.68	6.54 ± 1.67	0.391
PLT (109/L)	229.14 ± 77.31	240.92 ± 76.73	0.248	231.05 ± 70.18	231.62 ± 50.56	0.974
Lymphocyte(109/L)	1.61 ± 0.59	1.63 ± 0.68	0.808	1.59 ± 0.68	1.71 ± 0.95	0.567
Monocyte(109/L)	0.46 ± 0.23	0.47 ± 017	0.667	0.40 ± 0.14	0.70 ± 1.02	0.1
Neutrophil(109/L)	4.27 ± 1.55	4.54 ± 1.94	0.243	3.96 ± 1.51	4.47 ± 1.70	0.228
TG	1.47 ± 1.11	1.31 ± 0.60	0.18	1.43 ± 0.72	1.59 ± 0.98	0.502
Cholesterol	4.58 ± 0.88	4.72 ± 0.98	0.232	4.82 ± 0.89	4.91 ± 1.08	0.707
HDL	1.12 ± 0.28	1.19 ± 0.32	0.088	1.42 ± 1.51	1.13 ± 0.24	0.392
LDL	2.79 ± 0.69	2.93 ± 0.85	0.164	2.96 ± 0.84	3.18 ± 1.09	0.392
AproA	1.24 ± 0.19	1.26 ± 0.20	0.406	1.29 ± 0.17	1.22 ± 0.15	0.126
AproB	0.89 ± 0.19	0.90 ± 0.22	0.795	0.94 ± 0.18	0.89 ± 0.19	0.279
CEA (≥ 5 ng/mL)			0.016			0.173
No	94 (67.6)	45 (32.4)		28 (71.8)	11 (28.2)
Yes	54 (52.4)	49 (47.6)		12 (54.5)	10 (45.5)
CA19-9 (≥ 37 U/mL)			0.003			0.052
No	136 (64.8)	74 (35.2)		37 (71.2)	15 (28.8)
Yes	12 (37.5)	20 (62.5)		3 (33.3)	6 (66.7)
CT T stage			0.000			0.006
1/2	29 (85.3)	5 (14.7)		16 (88.6)	2 (11.1)
3	73 (66.4)	37 (33.6)		17 (68.0)	8 (32.0)
4	46 (46.9)	52 (53.1)		7 (38.9)	11 (61.1)

CEA: Carcinoembryonic antigen; CA19-9: Carbohydrate antigen 19-9; P < 0.05.