Copyright
©The Author(s) 2021.
World J Meta-Anal. Jun 28, 2021; 9(3): 297-308
Published online Jun 28, 2021. doi: 10.13105/wjma.v9.i3.297
Published online Jun 28, 2021. doi: 10.13105/wjma.v9.i3.297
Table 2 Patient arm characteristics
| Baseline characteristics | |||||||||||||||||
| Gender | Ethnic origin | OAD at screening | |||||||||||||||
| Ref. | Arms | M (%)/F (%) | White (%) | Black (%) | Asian (%) | Other (%) | Age (yr) | Bodyweight | BMI (kg/ m2) | Duration of Diabetes (yr) | HbA1 (%) | Hb (mmol/mol) | FPG (mmol/L) | Metformin | Metformin plus pioglitazone | Sulphonylurea | Other |
| Lingvay et al[25] | Degludec/liraglutide (n = 278) | 51.4/48.6 | 94.2 | 2.2 | 3.2 | 0.4 | 58.4 | 88.3 | 31.7 | 11.64 | 8.4 | NA | 8.9 | NA | NA | NA | NA |
| Glargine (n = 279) | 49.1/50.9 | 95.0 | 1.8 | 3.2 | 0.0 | 59.1 | 87.3 | 31.7 | 11.33 | 8.2 | NA | 8.9 | NA | NA | NA | NA | |
| Rosenstock et al[26] | LixiLan (n = 161) | 49.7/50.3 | 98.1 | NA | NA | NA | 56.9 | 90.1 | 32.2 | 6.3 | 8.1 | 64 | 9.8 | Yes | NA | NA | NA |
| Gla-100 (n = 162) | 52.5/47.5 | 98.8 | NA | NA | NA | 56.6 | 91.6 | 32.0 | 7.1 | 8.0 | 64 | 9.5 | Yes | NA | NA | NA | |
| Rosenstock et al[28] | iGlarLixi (n = 469) | 47.3/52.7 | 88.9 | 7.0 | 1.7 | 2.3 | 58.2 | NA | 31.6 | 8.9 | 8.1 | 65 | 9.9 | Yes | NA | 55.2 | Glinide, Sodium glucose co-transporter inhibitor, dipeptidyl dipeptidase 4 inhibitor |
| iGlar (n = 467) | 50.7/49.3 | 90.1 | 7.1 | 1.5 | 1.3 | 58.3 | NA | 31.7 | 8.7 | 8.1 | 65 | 9.8 | Yes | NA | 53.3 | ||
| Lixi (n = 234) | 56.8/43.2 | 92.3 | 5.1 | 1.3 | 1.3 | 58.7 | NA | 32.0 | 8.9 | 8.1 | 65 | 9.8 | Yes | NA | 52.6 | ||
| All (n = 1170) | 50.6/49.4 | 90.1 | 6.7 | 1.5 | 1.7 | 58.4 | NA | 31.7 | 8.8 | 8.1 | 65 | 9.8 | Yes | NA | 53.9 | ||
- Citation: Naidoo P, Bouharati C, Rambiritch V, Karamchand S, Tafuto BA, Leisegang RF. Glycated haemoglobin reduction and fixed ratio combinations of analogue basal insulin and glucagon-like peptide-1 receptor agonists: A systematic review. World J Meta-Anal 2021; 9(3): 297-308
- URL: https://www.wjgnet.com/2308-3840/full/v9/i3/297.htm
- DOI: https://dx.doi.org/10.13105/wjma.v9.i3.297