Significance of multivisceral resections in oncologic surgery: A systematic review of the literature

Table 3 Morbidity, mortality and survival rates after multivisceral resection for colon and rectal cancer

Study	Follow-up (mo)	Morbidity (%)	Mortality (%)	Survival1	Stage IV disease (%)	True pT4b (%)
Cukier et al[24]	36	36	0	3-yr OS: 85.9%; 3-yr DFS: 73.7%	0	67
Hallet et al[20]	54	33.3	0	90%; 5-yr DFS: 63.5%	0	50
Kumamoto et al[15]	32	17.8	0.8	87%	12	45
Leijssen et al[2]	48.5	25	0	5-yr OS (pT3): 63%; 5-yr OS (pT4): 70%	0	24
López-Cano et al[49]	74.9	47.8	7.1	48%; 5-yr DFS: 46.3 mo	20	65
Rosander et al[7]	28	37% (≥ Grade III)	5	60.8% for the infiltration group; 86.9% for the inflammation group	0	63
Takahashi et al[12]	48.4	LAP: 7 OPEN: 36	0	3-ys OS (open): 79.8%; (lap): 92.8%	25	50
Tei et al[23]	34	37.9	0	3-yr OS Stage II-III (S-MVR/M-MVR): 81.8%/80.0% 3-yr DFS Stage II-III (S-MVR/M-MVR: 58.3%/70.0%	28	34
Chen et al[6]	NR	11.5	NR	59% (Colon/inflammation) 39% (Colon/invasion) 63% (Rectum/inflammation); 42% (Rectum/invasion)	54	55
Eveno et al[58]	48	12	1.3	77%; 3-yr OS (without stage IV disease): 89%; 5-yr DFS: 58%	13	65
Fujisawa et al[29]	42 (mean)	NR	NR	3-yr OS (colon/bladder sparing): 90%; (colon/nonsparing): 67%; 3 yr OS (rectal/bladder sparing): 50%; (rectal/nonsparing): 67%	NR	NR
Hoffmann et al[21]	NR	34.6	7.7	55% (if curative)	49	63
Gezen et al[18]	25 (mean)	24.4	4.4	69.4%	12	34
Kim et al[17]	35/40 (mean)	LAP: 21 OPEN: 44	0	LAP: 60.5%; OPEN 48%	33	44
Laurence et al[56]	NR	NR	NR	52.7%	3	NR
Lehnert et al[8]	71	33	7.5	51%	5	50
Li et al[16]	64.3	61	5.6	50%; 59%: if curative	21	47
Park et al[53]	NR	35.2	3.1	58%	0	44
Rizzuto et al[57]	NR	55	0	3-yr OS (non-occlusive): 58.4%; (occlusive): 33.3%	0	77
Winter et al[1]	84	18	1.5	57%; 61% (R0); 17% (R1) 77% (R0, N0); 28% (R0, N+)	NR	54
Banmura et al[56]	32	50	0	Local recurrence rate: 30%	33	63
Crawshaw et al[25]	27.8	57.4	0	49.2%; 5-yr DFS: 45.3%	0	39
Derici et al[48]	40.4 (mean)	38.6	3.5	49%; 3-yr OS: 81.6%	0	58
Dinaux et al[50]	38.2	72.4	0	OS: 45 mo	0	24
Dosokey et al[30]	32 (mean)	39	0	67%; 5-yr DFS: 79%	0	NR
Gannon et al[28]	40	43	0	48%; Primary: 65% Recurrent: 22%; 5-yr DFS. 38%; Primary: 52% Recurrent: 13%	NR	NR
Harris et al[19]	30	50	0	5-yr OS (R0): 48%; R1/R2: 33%	14	52
Ishiguro et al[54]	40	39.8	2.2	52%; 5-yr DFS: 46%	NR	49
Mañas et al[13]	28.8	76.6	10	36.7%	20	67
Nielsen et al[9]	12	51	2.2	5-yr OS (primary): 46%; (recurrent):17%	0	NR
Pellino et al[14]	NR	54.9	2.4	67%	NR	70
Rottoli et al[10]	32.5/56.6	33 Primary: 32% Recurrent: 33%	4	5-yr DFS (primary): 46% (recurrent): 24%	NR	NR
Sanfilippo et al[51]	NR	25	NR	4-yr OS: 69%	0	44
Shin et al[22]	30	41.7	0	80%	27	23
Smith et al[47]	NR	47.6	0.8	53.3%; M0: 59%	20	44
Vermaas et al[11]	28 (mean)	69; Primary: 61; Recurrent: 83	3	52% (primary); 3-yr OS (recurrent): 32%	NR	43

¹if not specified 5-yr OS is reported. S-MVR: Single-port laparoscopic multivisceral resection; M-MVR: Multi-port laparoscopic multivisceral resection; NR: Not reported.