Hepatic gastrointestinal stromal tumor: Systematic review of an exceptional location

Table 4 Pathological, immunohistochemical and molecular findings, and risk of malignancy according to Fletcher et al[2]

Ref.	Yr	Age / Sex	Cell type	Molecular analysis	Mitotic count (nº / 50 HPF)	IH	Risk of malignancy
Hu et al[20]	2018	79/F	Spindle cells	NA	NA	CD117+, CD34+	NA
Joyon et al[21]	2018	56/M	Spindle cells	NA	8	CD117+, CD 34+	High risk
	2018	59/F	Mixed (spindle and epithelioid)	6 bp deletion in KIT exon 11	42	CD117+	High risk
Carrillo et al[22]	2017	41/M	Spindle cells	9 deletion in KIT	5	CD 117+, CD 34-	High risk
Lok et al[23]	2017	50/F	Spindle cells	NA	70	CD117+, CD 34+	High risk
Cheng et al[24]	2016	63/M	Spindle cells	NA	>5	CD 117 +, CD 34-	High risk
Nagai et al[25]	2016	70/F	Spindle cells	NA	40	CD117+, CD 34+	High risk
Liu et al[26]	2016	NA	NA	NA	NA	NA	NA
Wang et al[27]	2016	61/M	Spindle cells	NA	NA	CD117+/CD34+	High risk
Liu et al[28]	2016	56/F	Spindle cells	NA	2	CD117+	Low risk
Su et al[29]	2015	65/M	Spindle cells	NA	5	CD117+, CD 34-	High risk
Bhoy et al[3]	2014	41/F	NA	NA	NA	CD 117+	High risk
Lin et al[30]	2015	67/F	Mixed (spindle and epithelioid)	Mutation in exon 11	8	CD117+, CD 34+	High risk
Mao et al[31]	2015	60/F	Spindle cells	Mutation in exon 11	>10	CD 117+, CD 34 -	High risk
Kim et al[32]	2014	71/M	Spindle cells	NA	30-32	CD117+	High risk
Louis et al[33]	2014	55/F	Spindle cells	NA	10	CD117+	High risk
Zhou et al[34]	2014	56/M	Spindle cells	NA	<5	CD117+/CD34+	Intermediate
Li et al[35]	2012	53/M	Spindle cells	NA	NA	CD117+, CD34+	High risk
Yamamoto et al[36]	2010	70/M	Epithelioid cells	mutation PDGFRA exon 12	1	CD 117-/CD34+	High risk
Luo et al[37]	2009	17/M	Spindle cells	NA	0	CD117+, CD 34+	Low risk
Ochiai et al[38]	2009	30/M	Mixed (spindle and epithelioid)	No mutation at exon 11	75	CD117+, CD 34+	High risk
De Chiara et al[1]	2006	37/M	Spindle cells	NA	20	CD117+, CD 34+	High risk
Hu et al[6]	2003	79/F	Spindle cells	NA	20	CD117+, CD 34+	Low risk

M: male; F: female; NA: not available; PDGFRA: Platelet derived Growth Factor Receptor Alpha; HPF: High Power Fields.