Higher dose of simethicone decreases colonic bubbles and increases prep tolerance and quality of bowel prep: Meta-analysis of randomized controlled trials

Table 2 Sensitivity analyses

	PEG purgatives	NaP purgatives	Simethicone dose above the mean (478 mg)	Simethicone dose below the mean(478 mg)
Inadequate bowel preparation	0.44 (0.26-0.73), P = 0.002, n = 6	0.82 (0.41-1.67), P = 0.59, n = 2	0.61 (0.38-0.98), P = 0.04, n = 4	0.29 (0.07-1.18), P = 0.08, n = 4
Significant bubbles	1.42 (1.2-1.7), P < 0.0001, n = 7	1.84 (1.1-2.9), P = 0.01, n = 2	1.79 (1.26-2.53), P = 0.001, n = 3	1.37 (1.17-1.59), P < 0.0001, n = 6
ADR	NA	NA	1.08 (1.03-1.15), P = 0.003, n = 2	1.0 (0.85-1.19), P = 0.98, n = 2

PEG: Polyethylene glycol; NaP: Sodium phosphate; N/A: Not available; n: Number of studies; ADR: Adenoma detection rate.