Copyright
©The Author(s) 2016.
World J Meta-Anal. Oct 26, 2016; 4(5): 105-117
Published online Oct 26, 2016. doi: 10.13105/wjma.v4.i5.105
Published online Oct 26, 2016. doi: 10.13105/wjma.v4.i5.105
Table 4 Isolated hepatic perfusion morbidity and mortality
| Ref. | Mortality | Toxicity grade 3/4 (%) | Complications grade 3/4 (%) | |||||||||
| Bilirubin | Transaminases | Alkaline phosphatase | Neutropenia | Platelets | Anemia | Hepatic artery obstruction | Hepatic failure | Bleeding | Hypotension | Wound infection | ||
| Olofsson et al[55] | None | NR | NR | NR | NR | NR | NR | 2.90% | NR | NR | NR | NR |
| Magge et al[56] | 3.30% | 20.50% | 50.00% | 3.40% | 2.30% | 18.20% | 50.00% | NR | 5.70% | NR | 0% | 3.40% |
| Fukumoto et al[57] | NR | NR | 77.90% | NR | 44.10% | NR | NR | NR | NR | 1.50% | NR | 8.80% |
| Alexander et al[58] | 4% | 46.70% | 55.80% | 4.20% | 0.80% | 10.00% | NR | NR | 3.30% | 0.80% | 5.80% | 2.50% |
| van Iersel et al[59] | 6% | 18.00% | 20.00% | 15.20% | 2.90% | NR | NR | 1.90% | NR | 8.60% | NR | NR |
| Rizell et al[60] | 22% | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR | NR |
| Pingpank et al[61] | None | 18.9% (hepatic toxicity) | 66.20% | 35.10% | 17.60% | NR | NR | NR | NR | NR | ||
| Alexander et al[62] | None | 65.5% (hepatic toxicity) | NR | NR | NR | NR | NR | NR | NR | NR | ||
| Pooled P 95%CI | 5.4% (2.5%-11.2%) | 10.3 (2%-39%) | 19.2 (8.7%-37.2%) | 31.9% (9.3%-68.1%) | 2.2% (0.7%-6.6%) | 4.5% (2.3%-8.4%) | 4.50% (1.8-11.1%) | 2.7% (0.3%-20.3%) | 5.7% (3.1%-10.2%) | |||
- Citation: Meng T, Li GQ, Dai MH. Isolated hepatic perfusion for unresectable hepatic malignancies: A systematic review and meta-analysis. World J Meta-Anal 2016; 4(5): 105-117
- URL: https://www.wjgnet.com/2308-3840/full/v4/i5/105.htm
- DOI: https://dx.doi.org/10.13105/wjma.v4.i5.105