Antibiotics for eradicating meningococcal carriages: Network meta-analysis and investigation of evidence inconsistency

doi:10.13105/wjma.v4.i4.77

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World Journal of Meta-Analysis

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Meta-Analysis

World J Meta-Anal. Aug 26, 2016; 4(4): 77-87
Published online Aug 26, 2016. doi: 10.13105/wjma.v4.i4.77

Table 3 Results of network meta-analysis of antibiotics for preventing meningococcal infections (odds ratio of failure to eradicate)

	2 Rifampin	3 Ciprofloxacin	4 Cephalexin	5 Minocycline	6 Ampicillin	7 Penicillin	8 Ceftriaxone	9 Rifampin + minocycline	10 Azythromycin	11 Spectinomycin	12 Coumermycin A1	13 Sch29482	14 Sulphadiazine	15 Sulphadimidine
1 Placebo	0.038^a	0.020^a	0.274	0.058^a	0.267	0.611	0.009^a	0.004^a	0.071^a	5.971	5.524	0.498	0.487	23.17
2 Rifampin		0.53	7.201	1.536	7.028^a	16.20^a	0.247	0.098	1.89	156.2^a	146.2^a	13.15^a	12.88^a	601^a
3 Ciprofloxacin			13.7	2.911	13.29^a	30.67^a	0.467	0.184	3.54	301.0^a	278.0^a	24.87^a	24.4^a	1174^a
4 Cephalexin				0.214	0.980	2.26	0.035^a	0.013^a	0.262	22.42	20.6	1.826	1.825	91.1^a
5 Minocycline					4.577	10.52	0.161	0.064	1.212	102.3^a	95.57^a	8.53	8.42^a	396^a
6 Ampicillin						2.291	0.035^a	0.014^a	0.266	22.54	20.85^a	1.864	1.84	88.6^a
7 Penicillin							0.015^a	0.006^a	0.116	9.808	9.128	0.81	0.8	39.09
8 Ceftriaxone								0.385	7.566	620^a	597^a	53.17^a	52.94^a	2493^a
9 Rifampin + minocycline									20.15	1776^a	1584^a	140.2^a	134.3^a	7088^a
10 Azythromycin										83.64^a	78.9^a	7.03	7	334^a
11 Spectinomycin											0.924	0.082	0.084	4.032
12 Coumermycin A1												0.089	0.088	4.372
13 Sch29482													0.992	48.75
14 Sulphadiazine														47.14

^a95%CIs did not contain zero.

Citation: Abdelhamid AS, Loke YK, Abubakar I, Song F. Antibiotics for eradicating meningococcal carriages: Network meta-analysis and investigation of evidence inconsistency. World J Meta-Anal 2016; 4(4): 77-87
URL: https://www.wjgnet.com/2308-3840/full/v4/i4/77.htm
DOI: https://dx.doi.org/10.13105/wjma.v4.i4.77