Antireflux surgery vs medical treatment for gastroesophageal reflux disease: A meta-analysis

Table 2 Summary of inclusion criteria and relevant outcomes for the 7 studies included in meta-analysis

Ref.	Inclusion criteria	Relevant outcomes
Mahon et al[14]	Symptoms of GERD for at least 6 mo and pathologic reflux	PGWBI, GI well-being score, DeMeester score, pH testing
Mehta et al[15]	Symptoms of GERD for at least 6 mo and pathologic reflux pathologic reflux	DeMeester symptom score
Grant et al[16,17]	Symptoms of GERD requiring maintenance treatment with PPI (or other) for at least 12 mo, pathologic reflux	REFLUX quality-of life-score, EQ-5D, SF-36
Lundell et al[6,18]	Chronic GERD with concomitant esophagitis and response to omeprazole	PGWBI, GSRS
Anvari et al[19,20]	Chronic GERD, PPI for at least 1 yr, pathologic reflux, symptom control	GERSS, 24 h pH monitoring, EQ-5D
Spechler et al[21]	Complicated GERD(abnormal acid reflux at least 1 of the 4 disorders: Barrett esophagus, peptic esophageal ulcer, peptic esophageal stricture, or erosive esophagitis)	GRACI scores, 24 h pH monitoring, SF-36
Lundell et al[22] and Galmiche et al[23]	Chronic GERD, assessed through endoscopy, 24 h pH-metry and response to esomeprazole. Esophagitis no more than LA grade B, GERD symptoms no more than mild	GSRS

GERD: Gastroesophageal reflux disease; PPI: Proton pump inhibitor.