Is the traditional Chinese medicine helpful for patients with hematologic malignant diseases? A meta-analysis of randomized controlled trials

Table 25 Characteristics of included studies

Studies	Age	Sex (male:female)	Race	Disease	No. of participants	Intervention		Published
					(TCM:control)	TCM	Control	language
Dian Rong 2009[15,21,25,31,33]	TCM 39.52 ± 18.87	TCM 50:21	Chinese	Acute leukemia	71:66	Compound Zhe Bei granule +	Placebo + standard	English
	Control 37.94 ± 18.55	Control 39:27				standard chemotherapy	chemotherapy
Mao Sheng 2007[26,27]	TCM 35.63 ± 6.46	TCM 33:27	Chinese	Acute myeloid leukemia	60:60	Yi Qi Jie Du Huo Xue decoction	Standard western	Chinese
	Control 36.57 ± 7.38	Control 31:29				+ standard western mechicine	mechicine
sHai Yan 2007[22]	TCM 18-65	TCM 5:3	Chinese	Chronic myelogenous leukemia	8:10	Qu Du Hua Yu decoction	Hydroxyurea	Chinese
	Control 19-63	Control 7:3				+ hydroxyurea
sWei Hong 2013[23]	TCM 25-60	TCM 22:14	Chinese	Chronic myelogenous leukemia	22:17	TCM + interferon-α	Interferon-α	Chinese
	Control 25-65	Control 17:7
Chuan Xin 2013[32]	TCM 4.30 ± 1.81	TCM 12:8	Chinese	Pediatric acute myeloid leukemia	20:20	TCM + standard chemotherapy	Standard chemotherapy	Chinese
	Control 4.95 ± 2.04	Control 10:10
Ji Hong 2011[34]	TCM 60-71	TCM 16:16	Chinese	Elderly acute myeloid leukemia	32:28	TCM + HAG chemotherapy	HAG chemotherapy	Chinese
	Control 61-72	Control 15:13
Rui Rong 2004[29]	TCM 12-78	TCM 40:28	Chinese	Acute myeloid leukemia	68:46	TCM + standard chemotherapy	Standard chemotherapy	Chinese
	Control 11-76	Control 27:19
Su Juan 2005[24]	TCM 32.5 ± 12.45	TCM 16:14	Chinese	Acute leukemia	30:30	Qing Re Jie Du kang Bai decoction	Standard chemotherapy	Chinese
	Control 31.53 ± 12.41	Control 17:13				+ standard chemotherapy
Wen Jiang 2010[30]	TCM 47-78	TCM 17:12	Chinese	Acute myeloid leukemia	29:28	Shen Qi Qing Re Ke Li	HAG chemotherapy	Chinese
	Control 46-79	Control 15:13				+ HAG chemotherapy
Xiu Mei 1997[35]	TCM 6-73	TCM 72:40	Chinese	Non-Hodgkin lymphoma	112:55	TCM + standard chemotherapy	Standard chemotherapy	Chinese
	Control 6-71	Control 36:19
Ying Fei 2005[28]	TCM 13-72	TCM 22:10	Chinese	Acute leukemia	32:33	Shen Qi Fu Zheng	Standard chemotherapy	Chinese
	Control 15-71	Control 25:8				injection + standard chemotherapy

TCM: Traditional Chinese medicine; HAG: Homoharringtonine + cytoarabine + granulocye colony stimulating factor.