Unsaturation index and type 2 diabetes: Unknown, unloved

Table 2 Calculated unsaturation indices based on erythrocyte fatty-acid compositions reported by several studies

Disease	Participants (n)		Erythrocyte membrane	Unsaturation index1		Decrease (%)	Ref.
	Controls	Disease		Controls	Diabetic subjects
T2D/T1D	18	13/1	Total phospholipid	155.4	134.3	13.5	[5]
T2D/T1D + mild DR	18	11/1	Total phospholipid	155.4	125.9	19.0	[5]
T2D/T1D + moderate DR	18	11/1	Total phospholipid	155.4	119.5	23.1	[5]
T2D/T1D + severe DR	18	19/3	Total phospholipid	155.4	124.7	19.7	[5]
T2D/T1D + proliferative DR	18	17/7	Total phospholipid	155.4	136.9	11.9	[5]
Gestational diabetes	61	53	PC + PE	162.8	137.1	16.3	[6]

¹The unsaturation index was calculated as the mean number of double bonds per fatty acid residue multiplied by 100[4]. DR: Diabetic retinopathy; PC: Phosphatidylcholine; PE: Phosphatidylethanolamine.