Association between SHBG (TAAAA)n and AR (CAG)n polymorphisms and PCOS risk: A meta-analysis

Table 2 Characteristics of studies on (CAG)n androgen receptor polymorphism and polycystic ovarian syndrome

Ref.	Year	Country	Race	PCOS			Controls			PCOS diagnostic
				Size	Mean	Std dev	Size	Mean	Std dev	criteria
Mifsud et al[23]	2000	Singapore	Asian	91	22.97	0.24	112	23.09	0.23	A
Hickey et al[37]	2002	Australia	Caucasian	122	23	2.025	83	22.34	2.094	B
Jääskeläinen et al[43]	2005	Finland	Caucasian	106	21.5	2.2	112	21.5	2.1	C
Kim et al[39]	2008	South Korea	Asian	114	23.3	1.8	205	23.1	2	D
Ferk et al[38]	2008	Slovene	Caucasian	102	22.4	3.5	110	21.9	3.5	E
Liu et al[27]	2008	China	Asian	148	22.88	1.76	104	22.85	1.6	D
Shah et al[36]	2008 (1)	America	Caucasian	270	21.8	3.1	165	22.3	3.11	B
Shah et al[36]	2008 (2)	America	Black	37	20.1	3.44	84	20.2	3.08	B
Van Nieuwerburgh et al[40]	2008	Belgium	Caucasian	97	21.93	2.122	31	21.823	3.112	NC
Dasgupta et al[41]	2010	India	Asian	250	18.74	0.13	299	18.73	0.12	D
Laisk et al[34]	2010	Estonia	Caucasian	32	21.5	1.6	79	21.6	1.8	D
Robeva et al[44]	2010	Bulgaria	Caucasian	52	21.6	2.62	41	21.3	3.71	D
Skrgatic et al[42]	2011	Croatia	Caucasian	214	22.1	3.4	209	21.9	3.2	D
Schüring et al[35]	2011	Germany	Caucasian	72	21.43	1.87	179	21.99	2.07	D
Rajender et al[47]	2013	India	Asian	169	17.39	2.29	175	17.43	2.43	D

A: (1) Proven fertility; (2) No history of subfertility treatment; and (3) Normal menstrual cycles (25-32 d); B: National Institutes of Health criteria; C: (1) Non-hirsute; (2) Proven fertility; (3) Regular menstrual cycles; and (4) Normal ovaries; D: The criteria of Rotterdam Revised 2003 (two of three); E: (1) Oligo-/amenorrhea; (2) Polycystic ovaries; and (3) Hyper-androgenism. PCOS: Polycystic ovarian syndrome; NC: Unclear.