Comparison of functional outcomes after retropubic, laparoscopic and robot-assisted radical prostatectomy: A meta-analysis

Table 5 Comparative studies evaluating potency recovery after retropubic radical prostatectomy or robot-assisted radical prostatectomy

Quality	Case, n	Author, yr	Country	Age (y)	BMI (kg/m2)	Prostate vol-ume (mL, g)	Gleason sc-ore (biopsy)	PSA (ng/mL)	Study design	Potency definition	Data collection	Loss of follow-up (N/Y,%)	Potency recovery(UNS/BNS), %(n)		Potency recovery (unclear NS), %(n)
													6 mo	12 mo	6 mo	12 mo
3/2/3(H)	RRP, 100	Tewari et al[34], 2003	United States	63.1 (42.8-72)	27.6 (17-41)	48.4 (24.2-70)	-	7.3 (1.9-35)	Prospective	Presence of	Interview	-	Median: 440 d		Median:440 d
	RARP, 200			59.9 (40-72)	27.7 (19-38)	58.8 (18-140)		6.4 (0.6-41)		erection			Median: 180 da		Median:180 da
3/2/2(H)	RRP, 41	Ficarra et al[35], 2008	Italy	65 (61-69)	26 (24-28)	40 (30-47)	-	6 (5-10)	Prospective	IIEF-5 > 17	IIEF-5	N	-	49.0 (20/41)	-	-
	RARP, 64			61 (57-67)	26 (24-28)	37.5 (30-48)		6.4 (4.6-9)						81.0a (52/64)
3/2/3(H)	RRP, 81	Ham et al[36], 2008	South Korea	66.9 ± 6.0	23.6 ± 1.8	-	-	55.2 ± 23.7	Prospective	ESI	IIEF-5	N	-	40.7 (33/81)	-	-
	RARP, 164			67.3 ± 6.2	23.6 ± 2.3			22.3 ± 34.3						66.5 (109/164)
3/1/2(M)	RRP, 49	Di Pierro et al[37], 2010	Switzer- land	64.3 (59.1-68.0)	-	-	-	7.57 (5.1-10.4)	Prospective	ESI	Institutional	Y, > 20%	-	-	25.0 (12/49)	26.0 (12/47)
	RARP, 37			62.8 (58.4-67.0)				7.72 (5.6-12.1)			questionnaire				68.0 (25/37)	55.0 (12/22)
1/1/1(L)	RRP, 122	Kim et al[10], 2011	South Korea	66.5 ± 5.7	-	18.2 ± 23.4	-	14.6 ± 22.1	Prospective	ESI	Validated	N	-	-	6.7 (8/122)	28.1 (34/122)
	RARP, 373			64.2 ± 7.3		15.2 ± 20.2		10.4 ± 16.0			questionnaire				33.0 (123/373)	57.1 (213/373)
2/0/1(L)	RRP, 588	Krambeck et al[11], 2008	United States	61.0 (41.0-77.0)	-	-	-	5.0 (0.6-39.7)	Retrospective	ESI	Institutional	Y, > 20%	-	-	-	62.8 (262/417)
	RARP, 294			61.0 (38.0-76.0)				4.9 (0.5-33.5)			questionnaire					70.0 (142/203)
3/1/2(M)	RRP, 240	Rocco et al[40], 2009	Italy	63 (46-77)	-	-	6 (4-10)	6.7 (0.7-22.0)	Retrospective	ESI	Interview	Y, > 20%	-	-	31.0 (71/229)	41.0 (88/215)
	RARP, 120			63 (47-76)			6 (4-9)	6.9 (0.4-23.0)							43.0 (46/107)	61.0 (48/79)
3/1/3(H)	RRP, 2	Ou et al[41], 2009	United States	70.03 ± 6.10	24.09 ± 3.28	15.89 ± 14.15	6.22 ± 1.62		Retrospective	Presence of	Unspecified	N	-	50.0 (1/2)	-	-
	RARP, 16			67.27 ± 6.21	24.22 ± 3.16	16.45 ± 18.80	6.13 ± 0.9			erection				87.5.0 (14/16)
3/2/3(H)	RRP, 55	Choo et al[42], 2013	South Korea	67 ± 6.25	24 ± 2.73	42 ± 18.82		7.6 ± 19.33	Retrospective	ESI	IIEF-5	N	15.0 (8/55)	40.0 (22/55)	-	-
	RARP, 41			66 ± 7.75	24 ± 2.55	41 ± 15.77		7.2 ± 13.19					29.0 (12/41)	54.0 (22/41)

^aP < 0.05. RRP: Retropubic radical prostatectomy; RARP: Robot-assisted radical prostatectomy; ESI: Erection sufficient for intercourse; PSA: Prostate-specific antigen; IIEF-5: International index of erectile function; UNS: Unilateral nerve sparing; BNS: Bilateral nerve sparing.