Overview and a meta-analysis of pancreatic melanoma based on case reports

Table 1 Case reports of pancreatic malignant melanoma

Ref.	Age (yr)	Gender	Symptoms	History	Imaging	Treatment	Prognosis (mo)
Lei et al[5]	64	M	Abdominal pain, fatigue, weight loss	-	CT and MR showed a lesion located in the body and tail of the pancreas.	Surgical resection	-
Wu et al[6]	57	M	Abdominal pain, weight loss	-	CT showed a mass in the head of the pancreas	TP	6 +
Bergmann et al[7]	46	M	-	-	CT and MRI showed a lesion in the head of the pancreas	Whipple operation	4
Yang et al[8]	58	M	Abdominal pain, fatigue, weight loss	-	Ultrasound and CT showed atumor in the pancreas	TP	-
Solomons et al[9]	60	F	Nausea, abdominal pain, obstructive jaundice	-	Ultrasound and CT and MRI revealed a mass in the region of the pancreatic head	Bile duct stenting	8
Nikfarjam et al[10]	45	F	Abdominal discomfort	Ocular melanoma 12 yr ago	CT, PET-CT and MRI showed a mass in the head of pancreas	Pylorus-preserving pancreato-duodenectomy and segmental liver resection	6 +
	55	M	Abdominal pain	Ocular melanoma 13 yr ago	CT and PET-CT showed a mass in the head of the pancreas	TP	7 +
Kitamura et al[11]	74	M	-	-	Ultrasound and ERCP disclosed a cyst in the pancreas, communicating with a crater in the stomach.	Local resection	-
Stauch et al[12]	68	M	Obstructive jaundice	Melanoma in right ear 13 yr ago	Ultrasound. ERCP and CT revealed a mass in the head of the pancreas	Whipple operation	-
DeWitt et al[13]	33	M	Abdominal discomfort, obstructive jaundice		Ultrasound and CT demonstrated a mass in the head of the pancreas	Laparotomy	6
	83	F	Abdominal pain, hematochezia		CT and EUS found multiple lesions in the body and the tail of the pancreas	Supportive treatment	10
Dumitrascu et al[14]	43	F	-	Melanoma in the right eye 4 yr ago	Ultrasound found three metastases: (one in the body of pancreas and two in the right inferior pulmonary lobe)	Central pancreatectomy, right inferior pulmonary lobectomy	12 +
Minoguchi et al[15]	35	F	_	Melanoma in the vagina 2 yr ago, and metastasis to the lung 1 yr ago	CT and MRI found a mass in the head of the pancreas	Chemotherapy	4
Belagyi et al[16]	22	F	-	Melanoma in the back 9 yr ago, and metastasis to the right ovary 4 yr ago	CT showed the metastases tothe right ovary, the body of the pancreas, bowel and distal stomach, respectively	Resection of all metastases	4
Camp et al[17]	56	F	Right upper abdominal pain	Uveal melanoma of the left eye 6 yr ago	CT and PET-CT revealed a hepatic metastasis and a metastasis in the midbody of the pancreas	DP, mesohepatectomy and biochemotherapy with dacarbazine and interferon alpha	20 +

TP: Total pancreatectomy; DP: Distal pancreatectomy. M: Month; ST: Survival time; TP: Total Pancreatectomy; CT: Computed tomography; MRI: Magnetic resonance imaging; ERCP: Endoscopic retrograde cholangiopancreatography; PET: Positron emission tomography; EUS: Endoscopic ultrasonography.