Role of intestinal ultrasound in ulcerative colitis: A systematic review

Table 5 Summary of studies on contrast enhanced ultrasound in ulcerative colitis

Ref.	Study type	Number of patients	Parameters studied
Romanini et al[42]	Prospective	18 UC, 15 CD	High vascular density (CD34+; > 265 vessels per high power field, 40 ×) correlated with CEUS (higher and early peak, higher blood flow and volume)
Goertz et al[27]	Prospective	7 UC, 11 CD	Decrease in amplitude dependent CEUS parameters (peak enhancement and wash in rates). Time dependent parameters (e.g., time to peak) remained stable
Zhang et al[11]	Retrospective	13 IBD, 38 colon cancer	Disordered and heterogeneous enhancement in colon cancer (95% and 79%) compared to IBD (9% and 0%). Colon cancer: Later enhancement, slower washout with lower speed to peak intensity

CD: Crohn’s disease; IBD: Inflammatory bowel disease.