Comprehensive analysis of sodium polystyrene sulfonate-induced colitis: A systematic review

doi:10.13105/wjma.v11.i7.351

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Dec 18, 2023 (publication date) through Jul 20, 2024

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World Journal of Meta-Analysis

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2308-3840

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Meta-Anal. Dec 18, 2023; 11(7): 351-367
Published online Dec 18, 2023. doi: 10.13105/wjma.v11.i7.351

Table 3 Sodium polystyrene sulfonate characteristics – adapted from Rahman et al[13]

Indications	Mechanism of action	Administration	Dose (g)	Adverse effects (mild)	Adverse effects (serious)	Contraindications
Hyperkalemia	Resin exchanges sodium with potassium ions from the intestinal cells	Orally or rectally	Usually, 15 to 60 daily	Diarrhea, nausea, vomiting, loss of appetite, bloating	Ischemic colonic necrosis, constipation, seizures, confusion, abdominal pain, irregular heart beat	Hypokalemia, previous hypersensitivity to SPS, bowel obstruction, neonates with reduced gut motility

SPS: Sodium polystyrene sulfonate.

Citation: Aver GP, Ribeiro GF, Ballotin VR, Santos FSD, Bigarella LG, Riva F, Brambilla E, Soldera J. Comprehensive analysis of sodium polystyrene sulfonate-induced colitis: A systematic review. World J Meta-Anal 2023; 11(7): 351-367
URL: https://www.wjgnet.com/2308-3840/full/v11/i7/351.htm
DOI: https://dx.doi.org/10.13105/wjma.v11.i7.351