Systematic Reviews
Copyright ©The Author(s) 2023.
World J Meta-Anal. Dec 18, 2023; 11(7): 351-367
Published online Dec 18, 2023. doi: 10.13105/wjma.v11.i7.351
Table 3 Sodium polystyrene sulfonate characteristics – adapted from Rahman et al[13]
Indications
Mechanism of action
Administration
Dose (g)
Adverse effects (mild)
Adverse effects (serious)
Contraindications
Hyperkalemia Resin exchanges sodium with potassium ions from the intestinal cellsOrally or rectallyUsually, 15 to 60 dailyDiarrhea, nausea, vomiting, loss of appetite, bloatingIschemic colonic necrosis, constipation, seizures, confusion, abdominal pain, irregular heart beatHypokalemia, previous hypersensitivity to SPS, bowel obstruction, neonates with reduced gut motility