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©The Author(s) 2022.
World J Meta-Anal. Aug 28, 2022; 10(4): 220-237
Published online Aug 28, 2022. doi: 10.13105/wjma.v10.i4.220
Published online Aug 28, 2022. doi: 10.13105/wjma.v10.i4.220
Ref. | Design | Country | Year | Arms | NP | Age/yr | % males | NL | Tumour size, mean or median (range or SD)/mm | CPC (A/B/C) | F/U Duration/mo |
Abdelaziz et al[72], 2014 | RCT | Egypt | 2009-2011 | MWA | 66 | 53.6 (48.6-58.6) | 72.7 | 76 | 29 (19.3-38.7) | 25/41/0 | NR |
RFA | 45 | 56.8 (49.5-64.1) | 68.9 | 52 | 29.5 (19.2-39.8) | 24/21/0 | |||||
Chong et al[34], 2020 | RCT | Hong Kong | 2011-2017 | MWA | 47 | 63 (50–80) | 63.8 | NR | 31 (20–45) | 39/7/1 | 38.3 (2.3–78.0) |
RFA | 46 | 64.5 (42–5) | 82.6 | 28 (20–55) | 40/6/0 | 33.9 (4.9–72.7) | |||||
Kamal et al[35], 2019 | RCT | Egypt | 2017 | MWA | 28 | 55 (42-80) | 75 | 34 | 32.5 (23.3-41.7) | 22/6/0 | 12 |
RFA | 28 | 55 (42-80) | 78.6 | 34 | 32.8 (23.7-41.9) | 22/6/0 | 12 | ||||
Qian et al[36], 2012 | RCT | China | 2009-2010 | MWA | 22 | 52 (43–75) | 90.9 | 22 | 21 (17-25) | 22/0/0 | 5.1 ± 1.3 (2.8-6.5) |
RFA | 20 | 56 (43–76) | 95 | 20 | 20 (15-25) | 20/0/0 | 5.1 ± 1.3 (2.8-6.5) | ||||
Shibata et al[23], 2002 | RCT | Japan | 1999-2000 | MWA | 36 | 62.5 (52–74) | 66.7 | 46 | 22 (9–34) | 19/17/0 | 18 (6-27) |
RFA | 36 | 63.6 (44–83) | 72.7 | 48 | 23 (10–37) | 21/15/0 | 18 (6-27) | ||||
Tian et al[37], 2014 | RCT | China | 2014 | MWA | 120 | NR | NR | 86 | 26 (13-39) | NR | NR |
RFA | 79 | 22 (13-31) | |||||||||
Vietti et al[38], 2018 | RCT | France & Switzerland | 2011-2015 | MWA | 76 | NR | NR | 98 | NR | NR | 26 (18-29) |
RFA | 76 | 104 | 25 (18-34) | ||||||||
Yu et al[22], 2017 | RCT | China | 2008-2015 | MWA | 203 | NR | NR | 265 | 27 (7– 50) | NR | 35.2 (2.0–81.9) |
RFA | 200 | 251 | 26 (9–50) | 35.2 (2.0–81.9) | |||||||
Abdel-Samiee et al[33], 2020 | Retro | Egypt | 2020 | MWA | 50 | NR | NR | NR | NR | NR | 36 |
RFA | 50 | 36 | |||||||||
Bouda et al[39], 2020 | Retro | France | 2008-2016 | MWA | 79 | 62.8 (52.4-73.2) | 81 | 99 | 21.3 (13-29.6) | 71/8/0 | 34 (3–65) |
RFA | 43 | 62.2 (50.3-74.1) | 76.7 | 52 | 23.0 (14.9-31.1) | 39/4/0 | 40 (5–126) | ||||
Chinnaratha et al[40], 2014 | Retro | Australia | 2006-2012 | MWA | 101 | 62.1 (51.7-72.5) | 98 | NR | 21.1 (10.9-31.3) | 92/23/2 | 36 |
RFA | 25 | 62.1 (51.7-72.5) | 98 | 21.1 (10.9-31.3) | 36 | ||||||
Cillo et al[41], 2014 | Pros/Retro | Italy | 2004-2010 | MWA | 42 | 64 (47–81) | 83 | 50 | NR | 24 | |
RFA | 100 | 63 (34–81) | 83 | NR | 24 | ||||||
Ciruolo et al[42], 2020 | Retro | Italy | 2013-2019 | MWA | NR | 64 | 71.7 | 78 | NR | NR | NR |
RFA | 172 | ||||||||||
Ding et al[43], 2013 | Retro | China | 2006-2010 | MWA | 113 | 59.06 (30–86) | 75.2 | 131 | 25.5 (8–50) | 75/38/0 | 18.3 (3–51.4) |
RFA | 85 | 58.64 (40–77) | 80 | 98 | 23.8 (10–48) | 49/36/0 | 27.7 (4–60) | ||||
Du et al[44], 2020 | Retro | China | 2014-2016 | MWA | 218 | 56.3 (46.3-66.3) | 80 | 136 | 24 (13-35) | 107/8/0 | 28 (15-51) |
RFA | 234 | 57.5 (48-67) | 76.5 | 137 | 26 (15-37) | 105/10/0 | |||||
Gaia et al[45], 2021 | Retro | Italy | 2013-2019 | MWA | 81 | 67 (57–73) | 76.5 | 77 | 29 (20–35) | 71/10/0 | 20.4 (10.8-38.4) |
RFA | 170 | 63 (56–72) | 69.4 | 169 | 20 (15–25) | 148/22/0 | 34.8 (19.2–51.6) | ||||
Ghweil et al[46], 2019 | Pros | Egypt | 2019 | MWA | 25 | NR | NR | NR | NR | NR | NR |
RFA | 30 | ||||||||||
Iida et al[47], 2013 | Retro | Japan | 2001-2012 | MWA | 40 | 70.1 (63.5-76.7) | NR | NR | 20 (11-29) | NR | NR |
RFA | 18 | 73.5 (69.5-77.5) | 21 (16-26) | ||||||||
Ding et al[48], 2013 | Retro | China | 2002-2011 | MWA | 556 | 58.4 (48.1-68.7) | 74.8 | 1090 | 23 (12-34) | 466/167/22 | (6-75) |
RFA | 323 | 58 (47.8-68.3) | 79.8 | 562 | 22.8 (11.7-33.9) | 248/106/22 | (6-75) | ||||
Kuang et al[49], 2011 | Pros | China | 1997-2008 | MWA | 19 | 55 (27-74) | 94 | NR | NR | 77/4 /0 | 45 (24-155) |
RFA | 31 | ||||||||||
Kumbar et al[50], 2018 | Retro | India | 2018 | MWA | 25 | (40-85) | 92 | 33 | NR | 13/8/4 | 15 |
RFA | 25 | 88 | 35 | 17/8/0 | |||||||
Lee et al[51], 2017 | Retro | Hong Kong | 2003-2011 | MWA | 26 | 62.5 (49-79) | 73.1 | 28 | 37.5 (20-60) | 23/3/0 | 47.5 (11.3-62.5) |
RFA | 47 | 58 (43-77) | 85.1 | 52 | 31 (20-60) | 42/5/0 | 52.9 (3.6-121.8) | ||||
Liu et al[52], 2018 | Retro | China | 2002-2017 | MWA | 126 | 54 (45, 60) | 90.5 | 162 | 22.5 (17, 29) | NR | 36.8 (1-115) |
RFA | 436 | 56 (46, 65) | 89.7 | 482 | 23.0 (18, 30) | 34.1 (1-171) | |||||
Loriaud et al[53], 2018 | Retro | France & Switzerland | 2007-2015 | MWA | NR | 69 (61–75) | 92.5 | 40 | 22.5 (10–47) | 40/0/0 | 28 (10-46) |
RFA | 67 (58-74) | 85.8 | 120 | 21.3 (10-46) | 111/9/0 | ||||||
Lu et al[54], 2005 | Retro | China | 1997-2002 | MWA | 49 | 50.1 (24–74) | 89.8 | 98 | 25 (9–72) | 22/27/0 | 25.1 (2.0–50.6) |
RFA | 53 | 54.5 (20–74) | 81.1 | 72 | 26 (10–61) | 47/6/0 | 24.8 (2.0–51.0) | ||||
Mocan et al[55], 2017 | Retro | Romania | 2010-2016 | MWA | NR | NR | NR | 22 | NR | NR | 12 (5.6-18.4) |
RFA | 79 | 22.8 (7.8-37.4) | |||||||||
Nocerino et al[56], 2016 | Retro | Italy | 2016 | MWA | 106 | NR | NR | 134 | 20.4 (11-37) | NR | 12 (5.6-18.4) |
RFA | 27 | 35 | 20.1 (7-34) | 22.8 (7.8-37.4) | |||||||
Ohmoto et al[57], 2008 | Retro | Japan | 2002-2006 | MWA | 49 | 64 (38–75) | 83.7 | 56 | 17 (8–20) | 31/14/4 | 33.5 (9.8-57.2) |
RFA | 34 | 67 (44–78) | 73.5 | 37 | 16 (7–20) | 20/11/3 | 25.9 (14.6-37.2) | ||||
Potretzke et al[58], 2016 | Retro | US | 2001-2013 | MWA | 99 | 61 (44–82) | 81.8 | 136 | 22 (20–23) | NR | 24 |
RFA | 55 | 62 (23–88) | 72.7 | 69 | 24 (22–26) | 31 | |||||
Sakaguchi et al[59], 2009 | Pros | Japan | 2009 | MWA | 142 | NR | NR | NR | NR | NR | NR |
RFA | 249 | ||||||||||
Santambrogio et al[60], 2017 | Retro | Italy | 2009-2015 | MWA | 60 | 70 (61.7-78.3) | 72 | NR | 21.5 (16.2-26.8) | 60/0/0 | 31 (15–46) |
RFA | 94 | 69 (60-78) | 73 | 19.2 (14.2-24.2) | 94/0/0 | ||||||
Sever et al[61], 2018 | Retro | Turkey | 2012-2015 | MWA | 20 | 63.6 (57.3-69.9) | 65 | 37 | 28 (18-38) | 14/4/2 | 12 (1-40) |
RFA | 20 | 64.3 (55.3-73.3) | 70 | 34 | 24 (13-35) | 11/4/5 | |||||
Shum et al[62], 2016 | Retro | Hong Kong | 2014-2015 | MWA | 22 | NR | NR | NR | NR | NR | 19 |
RFA | 44 | 18 | |||||||||
Simo et al[63], 2011 | Retro | US | 2006-2008 | MWA | 13 | 59.6 (49–72) | 54 | 15 | 23.1 (14–39) | 12/7/3 | 7 (2.5–10.5) |
RFA | 22 | 58 (45–79) | 86 | 27 | 25.3 (12–44) | 7/6/0 | 19 (1.5–31) | ||||
Suwa et al[64], 2021 | Retro | Japan | 2014-2020 | MWA | 72 | 74.9 (66.5-83.3) | 65.3 | NR | 17.7 (10.9-24.5) | 58/14/0 | 12 |
RFA | 72 | 74.4 (65.2-83.6) | 68.1 | NR | 17.6 (11.3-23.9) | 61/11/0 | 37.8 | ||||
Suwa et al[65], 2020 | Retro | Japan | 2016-2019 | MWA | 44 | 73.4 (65.7-81.1) | 68 | 52 | 17.2 (12.3-22.1) | 12/3/29 | NR |
RFA | 55 | 73.4 (65.7-81.1) | 80 | 70 | 17.7 (11.3-24.1) | 16/8/31 | |||||
Vogl et al[66], 2015 | Retro | Egypt | 2008-2010 | MWA | 28 | 60 (45-68) | 82.1 | 32 | 36 (9-50) | NR | NR |
RFA | 25 | 57 (40-64) | 76 | 36 | 32 (8-45) | ||||||
Xu et al[67], 2004 | Retro | China | 1997-2001 | MWA | 54 | 53.4 (24–74) | 86.6 | 112 | 25 (15-36) | 53/33/11 | 27.4 (2–53) |
RFA | 43 | 78 | 26 (12-40) | ||||||||
Xu et al[68], 2017 | Retro | China | 2007-2012 | MWA | 301 | 54.2 (43.2-65.2) | 78.1 | NR | 17 (14-20) | 278/23/0 | 53 (8–98) |
RFA | 159 | 54.0 (43-65) | 83 | 17 (14-20) | 140/19/0 | 62 (6–102) | |||||
Yin et al[69], 2009 | Retro | China | 1997-2007 | MWA | 49 | 53 (41-65) | 87.2 | NR | 39 (31-47) | NR | 22 (2.2-93.5) |
RFA | 59 | ||||||||||
Zhang et al[70], 2013 | Retro | China | 2006 | MWA | 77 | 54 (26–76) | 70.2 | 105 | NR | 77/0/0 | 24.5 (6–64) |
RFA | 78 | 54 (30–80) | 82.1 | 93 | 78/0/0 | 26.3 (7–65.6) | |||||
Zhang et al[71], 2014 | Pros | China | 2014 | MWA | 45 | NR | NR | 60 | NR | NR | NR |
RFA | 56 | 68 |
- Citation: Tang MJ, Eslick GD, Lubel JS, Majeed A, Majumdar A, Kemp W, Roberts SK. Outcomes of microwave versus radiofrequency ablation for hepatocellular carcinoma: A systematic review and meta-analysis. World J Meta-Anal 2022; 10(4): 220-237
- URL: https://www.wjgnet.com/2308-3840/full/v10/i4/220.htm
- DOI: https://dx.doi.org/10.13105/wjma.v10.i4.220