Viral hepatitis: A narrative review of hepatitis A–E

Figure 1 Lifecycle of hepatitis B virus (HBV). 1: Attachment of the virion to the sodium taurocholate cotransporting peptide (NTCP); 2: Endocytosis; 3: Capsid release; 4: relaxed circular DNA entry into the nucleus; 5: closed covalent circular DNA synthesis; 6: Transcription; 7: mRNA transfer to the cytoplasm and encapsidation; 9: DNA synthesis and budding of virions into the endoplasmic reticulum lumen; 10: Virus release through multivesicular body transfer to hepatocyte surface.