Difference in incidence of developing hepatocellular carcinoma between hepatitis B virus-and hepatitis C virus-infected patients

Table 3 Hazard ratio for developing hepatocellular carcinoma for each item in various reports of patients with chronic hepatitis B virus infection

Ref.	Sex	Age	HBV-DNA	ALT	AFP	Presence of cirrhosis	HBV genotype	Alcohol use	Tabaco	DM
Kim et al[5]	2.782	1.080	0.986	2.641		2.955		2.105		2.00
Du et al[6]	2.94	3.30		2.55		2.45
Choi et al[7]	1.67	1.05	1.02	1.54	1.21	1.54
Wen et al[10]	1.93	5.34		1.93
Hann et al[11]				1.21						2.60
Chen et al[12]			3.12	5.75		7.961	2.05 (Type C)
Kumada et al[13]	6.011		5.125	3.939	6.779	18.033
Chen et al[14]	1.2	2.0	1.6	1.7				2.3	1.9
Ishiguro et al[15]				10.5	2.183
Ando et al[16]	2.200	3.395	1.442	1.914	1.967
Yamada et al[17]	1.44	5.867				5.59
Average	2.52	3.15	2.212	3.37		6.42

ALT: Alanine aminotransferase; AFP: α-fetoprotein; DM: Diabetes mellitus; HBV: Hepatitis B virus.