Copyright
©The Author(s) 2020.
World J Clin Cases. Aug 26, 2020; 8(16): 3405-3410
Published online Aug 26, 2020. doi: 10.12998/wjcc.v8.i16.3405
Published online Aug 26, 2020. doi: 10.12998/wjcc.v8.i16.3405
Table 1 Mechanisms of injury
| Angiotensin-converting enzyme 2 receptor | Expression on cholangiocytes (predominantly), hepatocytes |
| Immune mediated | Activation of system inflammatory response syndrome. Generation of a cytokine storm and pro-inflammatory state with multi-organ dysfunction. Stimulation of innate and cellular immunity. Activation of T killer lymphocytes |
| Medications | Acetaminophen. Antivirals (Remdesivir, lopinavir/Ritonavir, Oseltamavir). Antibiotics (macrolides). Janus kinase inhibitors. Methotrexate. Tocilizumab |
| Hypoxia-reperfusion injury | Hypotension and hypoxemia leading to hepatic ischemia |
- Citation: Chela HK, Pasha SB, Basar O, Daglilar E, Tahan V. Liver in the limelight in the corona (COVID-19) time. World J Clin Cases 2020; 8(16): 3405-3410
- URL: https://www.wjgnet.com/2307-8960/full/v8/i16/3405.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v8.i16.3405