Diagnostic pitfall of sebaceous gland metaplasia of the esophagus

Table 1 The clinical profile, pre-biopsy diagnosis, biopsy diagnosis, and pathological review of the 6 cases of sebaceous gland metaplasia

Case	Sex	Age	1st visit	Source	Symptom	1st ESP	1st End. Dx	Biopsy	Review	2nd ESP	2nd End. Dx	Biopsy	Review
1	M	46	1998	Outpatient	Peptic	Senior 1	Xanthoma	SGM	+
2	M	71	1999	Health screen	Denied	Senior 1	SGM	SGM	+
3	M	60	2002	Outpatient	Peptic	Senior 1	SGM	SGM	+	Senior 2	Xanthoma	-	-
4	M	65	2002	Health screen	Denied	Senior 2	Papilloma	SGM	-	Senior 4	Papilloma	-	-
5	F	49	2008	Health screen	Denied	Junior 2	Candidiasis	SGM	-	Junior 1	Negative	-	-
6	F	55	2012	Health screen	Denied	Senior 3	Candidiasis	-	-	Senior 3	Xanthoma	SGM	+

ESP: Endoscopist; End. Dx: Endoscopic diagnosis; Review: Pathological review; SGM: Sebaceous gland metaplasia.

Table 2 Rates of identification of sebaceous gland metaplasia by the senior and junior endoscopists

ESP (n)	End. study	End. biopsy (%)	End. biopsy/ESP	No. of ESP identifying SGM (%)	Identification episodes
Senior (7)	110022	16012 (14.5)1	2287.4	4 (57.1)2	83
Junior (26)	105024	19290 (18.4)1	741.9	2 (7.7)2	24
Total (33)	215046	35302 (16.4)	1069.8	6 (18.2)	10

¹P = 0.0001 using the χ² test;

²P = 0.01 using Fisher’s exact test;

³senior 1 in 3, senior 2 in 2, senior 3 in 2, and senior 4 in 1 meet;

⁴junior 1 in 1 and junior 2 in 1 case of identified SG. SGM: Sebaceous gland metaplasia; ESP: Endoscopist; End: Endoscopic.