Observational Study
Copyright ©The Author(s) 2022.
World J Clin Cases. Jul 16, 2022; 10(20): 6855-6864
Published online Jul 16, 2022. doi: 10.12998/wjcc.v10.i20.6855
Table 1 Comparison of patient clinico-pathological characteristics according to transection methods
Characteristics
CUSA (n = 40)
Water jet (n = 24)
P value
Pre-operative
Age (yr)72 (36-87)73 (54-83)0.588
Sex (male/female)28/1215/90.589
BMI (kg/m2)22.5 (16.0-28.0)22.5 (16.1-44.9)0.782
ASA-PS (1/2/3/4)2/29/9/00/15/8/10.290
Medical history of DM (yes/no)11/299/150.419
Chemical examination of blood
Creatine (mg/dL)0.72 (0.19-1.32)0.78 (0.48-8.10)0.244
Albumin (g/dL)4.15 (3.10-4.80)4.15 (3.50-4.90)0.895
Total bilirubin (mg/dL)0.75 (0.20-2.30)0.70 (0.20-1.20)0.198
Aspartate transaminase (IU/L)25 (14-134)24 (9-52)0.546
Alanine transaminase (IU/L)22 (10-125)21 (9-50)0.593
Platelet (× 105/μL)19 (8.8-84)23 (10.9-93)0.204
Prothrombin time (%)95.6 (49.1-127.5)99.7 (64.9-112.3)0.375
ICG-R15 (%)12 (3-27)12.5 (2-29)0.722
ICG (K)0.15 (0.06-0.24)0.15 (0.10-0.25)0.543
Child-Pugh grade (5/6/7 or more)34/6/022/2/00.699
Liver damage (A/B/C)39/1/023/1/00.999
Intra-operative
Operative procedure
Approach (open/laparoscopic)24/1624/0< 0.001
Hr (0 + S, 1, 2)23/7/108/8/80.151
Extrahepatic bile duct resection (yes/no)6/341/230.241
Operation time (min)235 (76-980)298 (187-543)0.061
Blood loss (mL)227.5 (0-1820)432 (95-1165)0.047
Post-operative
Clavien Dindo classification (0 or I/II/III/IV)32/4/4/014/3/7/00.118
Biliary fistula grade (none or A/B/C)38/2/022/2/00.627
Blood transfusion (include intraoperative)
Red blood cell (yes/no)1/392/220.551
Fresh frozen plasma (yes/no)5/357/170.113
Highest value of blood examination
Aspartate transaminase (IU/L)368 (40-1653)188 (37-1084)0.315
Alanine transaminase (IU/L)279.5 (37-2026)147 (33-1236)0.241
In hospital mortality00NA
Post-operative hospital stay (d)8 (5-57)8.5 (6-190)0.949
Histological diagnosis0.028
Hepatocellular carcinoma (%)18 (45)12 (50)
Intrahepatic cholangiocarcinoma (%)1 (2.5)6 (25)
Combined hepatocellular and cholangiocarcinoma (%)1 (2.5)1 (4.2)
Bile duct cancer (%)7 (30)0 (0)
Metastatic cancer (%)12 (2.5)4 (16.7)
Other (benign lesion) (%)1 (17.5)1 (4.2)
F (0, 1 or 2/3 or 4)28/1218/60.778
Table 2 Comparison of computed tomography values according to transection methods
Post-operative CT values
CUSA (n = 40)
Water jet (n = 24)
P value
Sum of dissection length (mm)95.3 (21.5-233.9)106 (50.6-236.1)0.081
Sum of denaturation area (mm2)522 (109.5-1242)324 (93.6-1529)0.059
Denaturation index (denaturation thickness, mm)5.8 (0.7-11.1)3.3 (1.7-10.4)< 0.001