Epstein-Barr virus-positive diffuse large B-cell lymphoma with human immunodeficiency virus mimicking complicated frontal sinusitis: A case report

Figure 2 Histopathologic features of the patient’s tumor. A: Tissue from the sinonasal cavity is mostly composed of necrotic abscess, except for the hypercellular tumorous area (arrows) surrounding the respiratory epithelium; B: On higher magnification, the large tumor cells show immunoblastic morphology with amphophilic cytoplasm and single prominent nucleoli (inset); C: Positive CD20 immunostaining highlights neoplastic large B cells, suggestive of diffuse large B-cell lymphoma; D: The tumor cells are diffusely positive for Epstein-Barr virus in situ hybridization.