Sarcomatoid carcinoma of the prostate with bladder invasion shortly after androgen deprivation: Two case reports

Table 1 Laboratory test results before the first and second surgery

Test	Case 1		Case 2		Normal reference range
	First TURP	Second TURP	First TURP	Second TURP
Blood
TPSA	37.12	7.19	< 4	0.01	0-4 ng/mL
FPSA	7.7	1.17	< 1.3	0	0-1.3 ng/mL
CRP	8.3	3.4	8.88	ND	0-10 mg/L
hs-CRP	3.21	1.08	< 3	ND	0-3 mg/L
IgG	12.82	12.92		ND	8-16 g/L
Alexin C3	1.14	1.2		1.04	0.9-1.5 g/L
Alexin C4	0.3	0.3		0.29	0.2-0.4 g/L
Creatinine	76	76	< 123	83	53-123 μmol/L
Platelets	193.92	231		283	100-300 × 109/L
ALP	111	72		88	25-135 g/L
LDH	235	214		126	114-240 g/L
SF	257	299		622	20-300 μg/L
Albumin globulin ratio	0.68	1.26		1.09	1-2.5
White blood cell count	5.03	5.41	< 9.15	8.78	3.97-9.15 × 109/L
Percent neutrophils	66.40%	72.20%		59.90%	45-77%
Percent lymphocytes	21.50%	16.20%		29.90%	20%-40%
Hemoglobin	115	106		119	131-172 g/L
MCV	91.35	90		87.3	86-100 fl
MCH	29.31	28.9		28.1	26-31 pg
D-Dimer	11.74	1.83		0.5	0-1 mg/L
FSH	13.52	ND	ND	53.5	1.5-12.5 mIU/mL
LH	10.18	ND	ND	27	1.7-8.6 mIU/mL
Testosterone	7.2	ND	ND	0.23	2.8-8 ng/mL
Urine
RBC	> 250	150	174	120	0-5 μL
WBC	> 400	5 μL	33.6	30	0-5 μL
CEA			5.7	5.23	≤ 5 ng/mL
IgM				2.72	0.5-2.2 g/L
IgG	12.82	12.92		14.86	8-16 g/L
C1q				269.87	159-233 mg/L
Immunohistochemistry
Positive		Vimentin (+++), Ki-67 (+, > 90%)		Ki-67 80%, P53 20%
Negative		CKpan, EMA, CK7, P504s, PSA		CK, CK5/6, P63, Gata-3, CD34, DES, SMA, myogenin, S100, HMB45, MelanA

CRP: C-reactive protein; ALP: Alkaline phosphatase; LDH: Lactate dehydrogenase; SF: Ferritin; MCV: Mean corpuscular volume; MCH: Mean corpuscular hemoglobin; FSH: Follicle stimulating hormone; LH: Luteinizing hormone; CEA: Carcinoembryonic antigen; RBC: Red blood cell; WBC: White blood cell; EMA: Epithelial membrane antigen; PSA: Prostate-specific antigen; CK: Creatine kinase; DES: Desmin; SMA: Smooth muscle actin; FPSA: Free prostate-specific antigen; TPSA: Total prostate-specific antigen.