Study on pathogenic genes of dwarfism disease by next-generation sequencing

Table 3 Concentration of insulin-like growth factor-1 and insulin-like growth binding protein 3 by growth hormone therapy after 6 mo

Number	IGF-1	After therapy	Fold change	IGFBP3	After therapy	Fold change
3	283	453	1.60	4.4	6.3	1.43
5	101	266	2.63	3.4	4.8	1.41
6	98.7	149	1.51	2.9	3	1.03
7	461	527	1.14	5.2	5.3	1.02
8	31.2	63.5	2.04	1.1	2.3	2.09
11	238	220	0.92	4.5	4.1	0.91
17	572	603	1.05	6.4	5.6	0.88
18	306	340	1.11	5.3	4.8	0.91
22	101	118	1.17	3.6	3.2	0.89
24	86	160	1.86	3.5	3.7	1.06
27	119	196	1.65	3.2	4.7	1.47
29	414	464	1.12	4.8	3.2	0.67
31	175	246	1.41	4.2	4.1	0.98
38	27.4	184	6.72	2	4.8	2.40

IGF-1: Insulin-like growth factor-1; IGFBP3: Insulin-like growth binding protein 3.