Copyright
©The Author(s) 2021.
World J Clin Cases. Feb 26, 2021; 9(6): 1386-1393
Published online Feb 26, 2021. doi: 10.12998/wjcc.v9.i6.1386
Published online Feb 26, 2021. doi: 10.12998/wjcc.v9.i6.1386
Table 2 Increase of transaminases during different chelator therapies
Therapy | Date of testing | ALT (U/L) | AST (U/L) | GGT (U/L) | Non-CP-bound copper (µg/dL) |
Trientine-2HCl | 02/16 | 38 | 24 | < 40 | < 15 |
03/16 | 47 | 28 | < 40 | < 15 | |
07/16 | 44 | 30 | < 40 | < 15 | |
09/16 | 42 | 30 | < 40 | < 15 | |
10/16 | 39 | 21 | < 40 | < 15 | |
11/17 | 34 | 24 | < 40 | < 15 | |
05/17 | 39 | 24 | < 40 | < 15 | |
10/17 | 56 | 30 | < 40 | < 15 | |
Trientine-2HCl + zinc | 01/18 | 69 | 36 | < 40 | < 15 |
04/18 | 24 | 23 | < 40 | < 15 | |
08/18 | 41 | 40 | < 40 | < 15 | |
10/18 | 66 | 30 | < 40 | < 15 | |
Trientine-2HCl | 05/19 | 174 | 61 | ND | < 15 |
Trientine-4HCl | 07/19 | 245 | 74 | 51 | < 10 |
08/19 | 285 | 80 | 76 | < 15 | |
09/19 | 297 | 90 | 67 | < 15 | |
10/19 | 367 | 81 | 87 | < 15 | |
11/19 | 417 | 107 | 76 | < 15 | |
D-penicillamine | 04/12/19 | 505 | 128 | 79 | < 15 |
10/12/19 | 571 | 147 | 77 | < 15 | |
17/12/19 | 409 | 109 | 78 | < 15 | |
D-penicillamine+Prednisolone | |||||
40 mg | 15/01/20 | 416 | 135 | 59 | < 15 |
40 mg | 30/01/20 | 268 | 79 | 56 | < 15 |
20 mg | 18/02/20 | 170 | 47 | 54 | < 15 |
5 mg | 15/03/20 | 84 | 37 | 33 | < 15 |
D-penicillamine alone1 | 25/03/20 | 168 | 60 | ND | < 15 |
20/4/20 | 117 | 48 | |||
29/5/20 | 127 | 46 |
- Citation: Stremmel W, Longerich T, Liere R, Vacata V, van Helden J, Weiskirchen R. Wilson disease — the impact of hyperimmunity on disease activity: A case report. World J Clin Cases 2021; 9(6): 1386-1393
- URL: https://www.wjgnet.com/2307-8960/full/v9/i6/1386.htm
- DOI: https://dx.doi.org/10.12998/wjcc.v9.i6.1386