De novo mutation loci and clinical analysis in a child with sodium taurocholate cotransport polypeptide deficiency: A case report

Table 1 Dynamic changes of liver function in the patient

Age (mo)	Day 5	2 mo 20 d	5 mo 20 d	9 mo	9 mo 16 d	10 mo 17 d	11 mo 2 d	11 mo 17 d	12 mo	13 mo 15 d	17 mo	20 mo
Total protein (65-85 g/L)	49	56.6	60.1	61.4	64.4	74.2	66.1	68.5	69	72	65.5	67
Glutamic pyruvic transaminase(7-40 μ/L)	43.2	45.4	40.2	38.4	42.6	61.8	21.9	8.7	11.2	32.2	18	21
Glutamic oxaloacetic transaminase (13-35 μ/L)	32.0	40.9	31.0	23.3	35.1	86.6	37.4	30.8	32.0	35.8	39.0	35.0
Albumin (40-55 g/L)	30.5	41.4	42.7	40.7	42.5	43.9	40.1	44.2	43.0	47.0	40.6	42.0
Alkaline phosphatase (< 28 IU/L)	400.0	573.6	572.0	479.2	384.2	327.0	336.0	461.7	432.0	342.9	472.0	435.0
Total bilirubin (3.4-17.1 μmol/L)	131.5	7.0	3.9	3.1	5.4	3.8	2.9	3.6	3.0	4.5	5.7	5.2
Indirect bilirubin (≤ 3.4 μmol/L)	126.3	3.3	2.3	2.6	3.0	1.3	2.4	3.1	2.5	3.2	2.4	2.8
Direct bilirubin (1.7-10.2 μmol/L)	5.2	3.6	1.6	0.5	2.4	2.5	0.5	0.5	0.5	1.3	3.3	2.4
Total bile acid (≤ 10 μmol/L)	231.9	193.0	239.6	235.1	210.7	543.3	576.1	533.0	220.0	180.2	145.4	137.0