Severe digital ischemia coexists with thrombocytopenia in malignancy-associated antiphospholipid syndrome: A case report and review of literature

Table 1 Main laboratory values in the present case

Item	Laboratory value	Reference value
RBC (1012/L)	3.68	3.8-5.1
WBC (109/L)	6.81	3.5-9.5
Platelet count (109/L)	41	150-450
D-dimer (mg/L)	0.82	< 0.55
Prothrombin time (s)	11.1	9.6-12.8
Activated partial thromboplastin time (s)	28.2	24.8-33.8
Fibrinogen (g/L)	2.82	2.0-4.0
International normalized ratio	0.98	0.88-1.15
Serum C-reactive protein (mg/L)	4.77	< 5
ESR (mm/h)	36	< 38
HIV	Negative	Negative
HBV	Positive	Negative
Syphilis	Negative	Negative
Serum complement C3 (g/L)	0.899	0.785-1.520
Serum complement C4 (g/L)	0.209	0.145-0.360
IgG (g/L)	10.6	8.0-15.5
IgA (mg/L)	950	836-2900
IgM (mg/L)	1240	700-2200
IgG anticardiolipin antibodies (GPLU/mL)	> 120	< 10
IgA anticardiolipin antibodies (APLU/mL)	57	< 10
IgM anticardiolipin antibodies (MPLU/mL)	4.24	< 10
IgG anti-β2 -glycoprotein-I (AU/mL)	> 200	< 20
IgA anti-β2 -glycoprotein-I (AU/mL)	90.1	< 20
IgM anti-β2 -glycoprotein-I (AU/mL)	2	< 20
Antinuclear antibody	+1:100	Negative
Lupus anticoagulant	Negative	Negative
Coombs’ test	Negative	Negative
Carcinoembryonic antigen (ng/mL)	1.87	< 5
α-fetoprotein	> 1210	< 7

RBC: Red blood cell; WBC: White blood cell; ESR: Erythrocyte sedimentation rate; HIV: Human immunodeficiency virus; HBV: Hepatitis B virus.