Serum magnesium level as a predictor of acute kidney injury in patients with acute pancreatitis

Table 3 Univariate predictors and multivariate model for acute kidney injury occurrence

Univariate analysis	OR	95%CI	P value	Multivariate model	OR	95%CI	P value
Mg2+ < 0.755, mg/dL	6.070	(3.374, 10.921)	< 0.001	Mg2+ < 0.755, mg/dL	5.525	(2.074, 14.718)	< 0.001
Age	0.981	(0.963, 1.000)	0.052	Age	0.966	(0.926, 1.007)	0.104
Gender	1.158	(0.652, 2.054)	0.617
BMI	1.155	(1.073, 1.244)	< 0.001	BMI	1.081	(0.946, 1.236)	0.251
APACHE II	1.385	(1.256, 1.527)	< 0.001	APACHE II	1.130	(0.976, 1.310)	0.103
SOFA	1.589	(1.307, 1.931)	< 0.001	SOFA	0.896	(0.604, 1.330)	0.585
CTSI	1.479	(1.279, 1.711)	< 0.001	CTSI	1.107	(0.815, 1.505)	0.516
Severity classification (MAP as reference)				Severity classification (MAP as reference)
MSAP	4.870	(2.071, 11.450)	< 0.001	MSAP	1.126	(0.240, 5.289)	0.880
SAP	84.857	(23.269, 309.458)	< 0.001	SAP	15.260	(1.817, 128.189)	0.012
Diabetes	1.379	(0.718, 2.647)	0.334
Hypertension	1.086	(0.588, 2.007)	0.791
Hyperlipidemia	0.886	(0.480, 1.634)	0.698
WBC	1.026	(0.970, 1.086)	0.910
Ly	0.734	(0.938, 1.046)	0.734
IL-6	1.006	(1.004, 1.009)	< 0.001	IL-6	1.003	(0.999, 1.006)	0.113
PCT	1.350	(1.166, 1.562)	< 0.001	PCT	1.109	(0.959, 1.283)	0.163
Platelets	1.003	(0.999, 1.007)	0.139
BUN	1.368	(1.196, 1.565)	< 0.001	BUN	1.102	(0.826, 1.470)	0.508
Creatinine	1.051	(1.034, 1.069)	< 0.001	Creatinine	1.052	(1.014, 1.091)	0.006
HCO3-	0.843	(0.794, 0.896)	< 0.001	HCO3-	0.993	(0.894, 1.103)	0.892
Cl-	1.100	(1.032, 1.172)	0.003	Cl-	1.042	(0.936, 1.160)	0.453

Mg²⁺: Magnesium; BMI: Body mass index; AKI: Acute kidney injury; SOFA: Sequential organ failure assessment; CTSI: CT severity index; MAP: Mild acute pancreatitis; MSAP: Mild severe acute pancreatitis; SAP: Severe acute pancreatitis; WBC: White blood cells; IL-6: Interleukin-6; PCT: Procalcitonin; BUN: Blood urea nitrogen; OR: Odds ratio; CI: Confidence interval.