Association between neutrophil-to-lymphocyte ratio and major postoperative complications after carotid endarterectomy: A retrospective cohort study

Table 3 Risk factors associated with major postoperative complications

	Statistical value	Post-CEA major complications	P
Age (yr)	62.0 ± 7.2	1.04 (0.99, 1.09)	0.151
Sex			0.616
Male	175 (84.95%)	1.0
Female	31 (15.05%)	0.77 (0.28, 2.15)
BMI (kg/m2)	25.33 ± 2.89	1.05 (0.93, 1.17)	0.459
ASA grade			0.522
Grade II	167 (81.07%)	1.0
Grade III	39 (18.93%)	1.32 (0.57, 3.05)
Anesthesia methods			0.312
TIVA	163 (79.13%)	1.0
Combined intravenous–inhalation anesthesia	43 (20.87%)	0.62 (0.24, 1.58)
Degree of carotid artery stenosis on the surgical side
Mild/moderate stenosis	3 (1.46%)	1.0
Severe stenosis	201 (97.57%)	0.47 (0.04, 5.28)	0.538
Occlusion	2 (0.97%)	2.00 (0.05, 78.25)	0.711
Degree of carotid artery stenosis on the contralateral side
Mild/moderate stenosis	169 (85.35%)	1.0
Severe stenosis	21 (10.61%)	0.38 (0.08, 1.69)	0.201
Occlusion	8 (4.04%)	0 (0, Inf)	0.986
Operating time (min)	141.33 ± 40.96	1.01 (1.0, 1.02)	0.038a
Intraoperative intake and output volume (mL)	897.57 ± 333.40	1.00 (1.0, 1.00)	0.221
Duration of carotid artery occlusion	22.0 (18.0–44.0)	1.01 (0.99, 1.03)	0.327
CVSBP	0.16 ± 0.04	16.36 (0.00, 150500.70)	0.548
CVDBP	0.15 ± 0.04	40.21 (0.01, 132798.95)	0.372
Preoperative NLR	2.08 ± 0.94	1.21 (0.87, 1.69)	0.264
NLR within 24 h after CEA	5.68 (3.93–8.91)	1.09 (1.01, 1.17)	0.026a

^aP < 0.05.

ASA: American society of anesthesiologists; BMI: Body mass index; CEA: Carotid endarterectomy; CV_DBP: Coefficient of variation in diastolic blood pressure; CV_SBP: Coefficient of variation in systolic blood pressure; NLR: Neutrophil to lymphocyte ratio; TIVA: Total intravenous anesthesia.