Intracuff alkalinized lidocaine to prevent postoperative airway complications: A meta-analysis

doi:10.12998/wjcc.v9.i34.10626

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Meta-Analysis

World J Clin Cases. Dec 6, 2021; 9(34): 10626-10637
Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10626

Table 2 Sensitivity analyses: The effect of potential biases on primary and secondary outcomes

Potential bias or limitations excluded	IPC RR (95%CI), I²	IPH RR (95%CI), I²	IPOST within 24 h RR (95%CI), I²	VAS of POST at 1 h RR (95%CI), I²	VAS of POST at 24 h RR (95% CI), I²
Overall	0.38 (0.23, 0.63), 82%	0.38 (0.21, 0.69), 74%	0.19 (0.09, 0.41), 0%	-18.30 (-22.79, -13.82), 73%	-14.86 (-15.75, -13.98), 43%
Only females	0.33 (0.20, 0.52), 69%	NE	NE
Cuff prefilling	0.35 (0.19, 0.63), 85%	NE	NE	-17.59 (-18.69, -16.49), 77%	-14.81 (-17.22, -12.41), 54%
A high risk of bias	NE	NE	0.19 (0.08, 0.48), 0%	-18.45 (-25.61, -11.29), 77%	-14.37 (-18.31, -10.43), 56%

IPC: Incidence of post-extubation cough; IPH: Incidence of postoperative hoarseness; POST: Postoperative sore throat; IPOST: Incidence of postoperative sore throat; VAS: Visual analogue scale; CI: Confidence interval; NE: Not estimable; RR: Relative risk.

Citation: Chen ZX, Shi Z, Wang B, Zhang Y. Intracuff alkalinized lidocaine to prevent postoperative airway complications: A meta-analysis. World J Clin Cases 2021; 9(34): 10626-10637
URL: https://www.wjgnet.com/2307-8960/full/v9/i34/10626.htm
DOI: https://dx.doi.org/10.12998/wjcc.v9.i34.10626