Remimazolam benzenesulfonate anesthesia effectiveness in cardiac surgery patients under general anesthesia

Table 4 Comparison of the serum levels of inflammatory factors between the two groups (mean ± SD)

Groups	Remimazolam group (n = 40)	Propofol group (n = 40)	t value	P value
TNF-α (pg/mL)
Before surgery	1.63 ± 0.46	1.80 ± 0.50	-1.583	0.118
12 h after surgery	3.74 ± 0.95	3.98 ± 1.03	-1.083	0.282
IL-6 (pg/mL)
Before surgery	54.83 ± 12.30	50.11 ± 10.86	1.819	0.073
12 h after surgery	87.55 ± 15.40	93.28 ± 14.81	-1.696	0.094
E (pg/μL)
Before surgery	1.58 ± 0.38	1.49 ± 0.40	1.032	0.305
12 h after surgery	2.52 ± 0.70	2.86 ± 0.76	-2.081	0.041
NE (pg/μL)
Before surgery	2.66 ± 0.48	2.48 ± 0.51	1.625	0.108
12 h after surgery	3.38 ± 0.75	3.73 ± 0.88	-1.914	0.059
COR (ng/mL)
Before surgery	22.73 ± 4.81	21.40 ± 4.36	1.296	0.199
12 h after surgery	34.20 ± 6.85	31.06 ± 5.72	2.225	0.029
GLU (mmol/L)
Before surgery	5.39 ± 0.51	5.50 ± 0.48	-0.993	0.324
12 h after surgery	6.18 ± 0.62	6.54 ± 0.75	-2.34	0.022

COR: Cortisol; E: Epinephrine; GLU: Glucose; IL-6: Interleukin-6; NE: Norepinephrine; TNF-α: Tumor necrosis factor alpha.