Lamb’s tripe extract and vitamin B12 capsule plus celecoxib reverses intestinal metaplasia and atrophy: A retrospective cohort study

doi:10.12998/wjcc.v9.i34.10472

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World Journal of Clinical Cases

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Retrospective Cohort Study

World J Clin Cases. Dec 6, 2021; 9(34): 10472-10483
Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10472

Table 3 Factors associated with regression of intestinal metaplasia and atrophic gastritis (multivariate analysis)

Regression effect	Factor	LTEVB₁₂			Celecoxib
Regression effect	Factor	OR	95%CI	P value	OR	95%CI	P value
IM	Fresh vegetable intake (> 100 g/d)	0.497	0.224-1.105	0.087	-	-	-
	High salt diet	1.852	1.044-3.285	0.035	-	-	-
	Tea intake (> 100g/d)	-	-	-	2.295	0.736-7.158	0.152
	Education level (≥ senior high school)	-	-	-	1.672	0.495-5.643	0.408
	Income level (≥ 5000 yuan/mo)	-	-	-	3.097	0.902-10.638	0.073
AG	Education level (≥ senior high school)	0.480	0.255-0.903	0.023	-	-	-
	Tea intake (> 100g/d)	0.678	0.388-1.185	0.173	-	-	-
	Profession (ref: Farmer)			0.169			-
	Officer	0.784	0.313-1.965	0.603	-	-	-
	Medic	-	-	-	-	-	-
	Teacher	1.897	0.620-5.804	0.262	-	-	-
	Merchant	1.028	0.361-2.933	0.958	-	-	-
	Technical staff	3.305	1.275-8.565	0.014	-	-	-
	Retired	1.878	0.791-4.458	0.153	-	-	-
	Unemployed	1.570	0.612-4.027	0.348	-	-	-
	Blood type (ref: A)			-			0.123
	B	-	-	-	2.021	0.240-17.033	0.518
	O	-	-	-	0.322	0.064-1.617	0.169
	AB	-	-	-	0.118	0.010-1.460	0.096
	Unknown	-	-	-	0.389	0.128-1.182	0.096

AG: Atrophic gastritis; CI: Confidence interval; IM: Intestinal metaplasia; ITT: Intention-to-treat; LTEVB₁₂: Lamb Tripe Extract and Vitamin B₁₂Capsule; OR: Odds ratio; PP: Per-protocol.

Citation: Wu SR, Liu J, Zhang LF, Wang N, Zhang LY, Wu Q, Liu JY, Shi YQ. Lamb’s tripe extract and vitamin B₁₂capsule plus celecoxib reverses intestinal metaplasia and atrophy: A retrospective cohort study. World J Clin Cases 2021; 9(34): 10472-10483
URL: https://www.wjgnet.com/2307-8960/full/v9/i34/10472.htm
DOI: https://dx.doi.org/10.12998/wjcc.v9.i34.10472