Lamb’s tripe extract and vitamin B12 capsule plus celecoxib reverses intestinal metaplasia and atrophy: A retrospective cohort study

Table 2 Intestinal metaplasia and atrophic gastritis regression rates of different operative link on gastritis assessment and operative link on gastric intestinal metaplasia assessment stages for each therapy group

Group	IM regression (%)					AG regression (%)
	Ⅰ stage	Ⅱ stage	Ⅲ stage	Ⅳ stage	P value	Ⅰ stage	Ⅱ stage	Ⅲ stage	Ⅳ stage	P value
LTEVB12	17.19	57.27a	70.97a	89.47a,b	< 0.001	33.33	40.63	66.67	100.00c,d	< 0.05
Celecoxib	57.14	31.37	71.60e	71.43e	< 0.001	-	30.00	50.00	76.20f	< 0.05

^aP < 0.05 vs control (IM regression of stage I in LTEVB₁₂ group).

^bP < 0.05 vs control (IM regression of stage II in LTEVB₁₂ group).

^cP < 0.05 vs control (AG regression of stage I in LTEVB₁₂ group).

^dP < 0.05 vs control (AG regression of stage II in LTEVB₁₂ group).

^eP < 0.05 vs control (IM regression of stage II in celecoxib group).

^fP < 0.05 vs control (IM regression of stage II in celecoxib group).

AG: Atrophic gastritis; IM: Intestinal metaplasia; ITT: Intention-to-treat; LTEVB₁₂: Lamb’s tripe extract and vitamin B₁₂ capsule; OLGA: Operative link on gastritis assessment; OLGIM: Operative link on the gastric intestinal metaplasia assessment.