Role of circular RNAs in gastrointestinal tumors and drug resistance

doi:10.12998/wjcc.v9.i34.10400

Advanced Search

BPG is committed to discovery and dissemination of knowledge

Home / Archive / Volume 9, Issue 34

This Article

Academic Content and Language Evaluation of This Article

CrossCheck and Google Search of This Article

Academic Rules and Norms of This Article

Citation of this article

Corresponding Author of This Article

Research Domain of This Article

Article-Type of This Article

Open-Access Policy of This Article

Times Cited Counts in Google of This Article

Number of Hits and Downloads for This Article

Total Article Views (4633)

All Articles published online

The chart showing PDF series, WORD series, HTML series, Figures (1-3) series, Tables (1-5) series.

Item

Count

PDF

304

WORD

104

HTML

1974

Figures (1-3)

735

Tables (1-5)

328

Sum=3445

Publishing Process of This Article

The chart showing Browse series, Download series.

Item

Count

Browse

413

Download

775

Sum=1188

Dec 6, 2021 (publication date) through Dec 4, 2024

Times Cited of This Article

Times Cited (4)

Journal Information of This Article

Publication Name

World Journal of Clinical Cases

ISSN

2307-8960

Publisher of This Article

Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

Review

World J Clin Cases. Dec 6, 2021; 9(34): 10400-10417
Published online Dec 6, 2021. doi: 10.12998/wjcc.v9.i34.10400

Table 3 circRNAs involved in colon cancer gene transcription regulation and drug resistance

Cancer type	circRNA	Gene expression		Mechanism	Drug	Ref.
Cancer type	circRNA	Up	Down	Mechanism	Drug	Ref.
Colon cancer	circNSUN2	↑		Interact with YTHDC1, SRSF3 and NXF1	NR	[91]
Colon cancer	hsa-circ-101555	↑		Acts as miR-597-5p sponge	NR	[92]
Colon cancer	circHIPK3	↑		Acts as miR-7 sponge	NR	[93]
Colon cancer	circCCDC66	↑		DHX9 phosphorylation	Oxaliplatin	[94,95]
Colon cancer	circ-001680	↑		Adjust BMI1 via miR-340	Irinotecan	[98]
Colon cancer	hsa-circ-0005963	↑		Acts as miR-122 sponge	Oxaliplatin	[99]
Colon cancer	circ-0000338	↑ or ↓		Knock out circ-0000338 improves drug resistance	5-FU	[100]
Colon cancer	hsa-circ-32883	↑		uncertain	5-FU, oxaliplatin	[101]
Colon cancer	circ0007031, circ0000504, circ0007006	↑		Use hsa-miR485-5p pathway	5-FU	[102]
Colon cancer	hsa-circ-0079662	↑		Using the TNF-α pathway	oxaliplatin	[103]
Colon cancer	circDDX17	↑		Adjustable via miR-31-5p/KANK1 axis	5-FU	[104]

NR: Not reported; circRNA: Circular RNA.

Citation: Xi SJ, Cai WQ, Wang QQ, Peng XC. Role of circular RNAs in gastrointestinal tumors and drug resistance. World J Clin Cases 2021; 9(34): 10400-10417
URL: https://www.wjgnet.com/2307-8960/full/v9/i34/10400.htm
DOI: https://dx.doi.org/10.12998/wjcc.v9.i34.10400