Is endoscopic retrograde appendicitis therapy a better modality for acute uncomplicated appendicitis? A systematic review and meta-analysis

Table 3 Pooled results of inflammatory factors and complications

Outcomes	Categories	Number of records	OR/WMD and 95%CI	P	Heterogeneity with groups (I2)	Phet value
Inflammatory factors
	C-reactive protein (pre)	3	-0.28, [-1.14, 0.58]	0.53	72%	0.03
	C-reactive protein (post)	3	-10.06, [-17.39, -2.73]	0.007	98.0%	< 0.001
	Tumor necrosis factor-α (pre)	2	-0.21, [-1.32, 0.90]	0.71	0.0%	0.68
	Tumor necrosis factor-α (post)	2	7.70, [-8.47, -6.93]	< 0.001	99.0%	< 0.001
	Interleukin 6 (pre)	3	-0.11, [-1.04, 0.82]	0.81	6.0%	0.34
	Interleukin 6 (post)	3	-9.78, [-10.69, -8.88]	< 0.001	99.0%	< 0.001
Complications
	Intestinal obstruction	4	0.19, [0.05, 0.79]	0.020	0.0%	0.95
	Abdominal infection	2	0.10, [0.01, 0.83]	0.030	0.0%	0.44
	Urinary tract infection	3	0.27, [0.04, 1.65]	0.160	0.0%	0.97