Effects of anti-diabetic drugs on sarcopenia: Best treatment options for elderly patients with type 2 diabetes mellitus and sarcopenia

doi:10.12998/wjcc.v9.i33.10064

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Nov 26, 2021 (publication date) through Dec 4, 2024

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World Journal of Clinical Cases

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2307-8960

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Baishideng Publishing Group Inc, 7041 Koll Center Parkway, Suite 160, Pleasanton, CA 94566, USA

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World J Clin Cases. Nov 26, 2021; 9(33): 10064-10074
Published online Nov 26, 2021. doi: 10.12998/wjcc.v9.i33.10064

Table 1 Effects of anti-diabetic drugs on patients with geriatric type 2 diabetes mellitus and sarcopenia

Anti-diabetic drugs	Effect on sarcopenia	Good option or poor option
Biguanides	Positive[31,33-36,38-40]/negative[41-44]	Unclear
Insulin secretagogues	Negative[46-48]	Poor
-Glucosidase inhibitors	No data	No data
Thiazolidinediones	Positive[35,53-56]	Careful use
Dipeptidyl peptidase IV inhibitors	Positive[57-60]/neutral[62]	Good
Glucagon-like peptide-1 receptor agonists	Positive[63,70,71]/negative[62]	Unclear
Sodium-glucose cotransporter-2 inhibitor	Positive[72,73]/unclear[6,74]	Unclear
Insulin	Positive/unclear[75]	Unclear

Citation: Ma XY, Chen FQ. Effects of anti-diabetic drugs on sarcopenia: Best treatment options for elderly patients with type 2 diabetes mellitus and sarcopenia. World J Clin Cases 2021; 9(33): 10064-10074
URL: https://www.wjgnet.com/2307-8960/full/v9/i33/10064.htm
DOI: https://dx.doi.org/10.12998/wjcc.v9.i33.10064