Botulinum toxin associated with fissurectomy and anoplasty for hypertonic chronic anal fissure: A case-control study

Figure 1 Duration of post-defecatory pain preoperatively and after fissurectomy and anoplasty with V-Y advancement flap alone (group I) and associated with botulinum toxin A injection in the internal anal sphincter (group II). Significant difference vs preoperative values: ^aP < 0.014; ^bP < 0.0001.