Colorectal cancer patients in a tertiary hospital in Indonesia: Prevalence of the younger population and associated factors

Table 5 Clinical manifestations of early- and late-onset colorectal cancer patients in 2008-2019

Variables	< 50-years-old, n (%)	≥ 50-years-old, n (%)	Total, n (%)	P
Smoking	69 (33.7)	114 (39.3)	183 (37)	0.199
Parental history of CRC	8 (3.9)	4 (1.4)	12 (2.4)	0.072
Other family history of CRC	6 (2.9)	8 (2.8)	14 (2.8)	0.911
Suspicion of FAP	4 (2.0)	6 (2.1)	10 (2.0)	0.927
Suspicion of HNPCCa	19 (9.3)	12 (4.1)	31 (6.3)	< 0.05
BMI
Underweightc	71 (34.6)	58 (20.0)	129 (26.1)	< 0.001
Normoweight	71 (34.6)	101 (34.8)	172 (34.7)	0.521
Overweight and obeseb	63 (30.7)	131 (45.2)	194 (39.2)	< 0.005
Comorbidities
Diabetes mellitusc	8 (3.9)	53 (18.3)	61 (12.3)	< 0.001
Hypertensionc	7 (3.4)	73 (25.2)	80 (16.2)	< 0.001

^aChi-square test, P < 0.05.

^bFisher’s exact test, P < 0.005.

^cFisher’s exact test, P < 0.001.

BMI: Body mass index; CRC: Colorectal cancer; FAP: Familial adenomatous polyposis; HNPCC: Hereditary nonpolyposis colorectal cancer.