Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer

Table 6 Occult liver and peritoneal metastasis according to each criteria, n (%)

Factor	n of patients	No. of patients with occult liver or peritoneal metastasis	Estimated reduction rate of exploratory laparotomy
CA19-9 > 255 U/mL	48 (20)	7	7/48 (14.6)
CEA > 7 ng/mL	26 (11)	6	6/26 (23.1)
NLR > 3	77 (33)	11	11/77 (14.3)
mGPS = B, C, D	101 (43)	5	5/101 (5.0)
Positive factors ≥ 2	73 (31)	11	11/73 (15.1)
Positive factors ≥ 3	26 (11)	7	7/26 (26.9)
Positive factors ≥ 4	6 (3)	2	2/6 (33.3)

CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; NLR: Neutrophil-lymphocyte ratio.