Risk factors for occult metastasis detected by inflammation-based prognostic scores and tumor markers in biliary tract cancer

Table 5 Sensitivity, Specificity and PPV for each biliary cancer

Variables (cut-off value)	Sensitivity	Specificity	PPV
Intrahepatic bile duct cancer
CA19-9 (255 IU/mL)	0.833	0.667	0.313
CEA (7 ng/mL)	0.500	0.849	0.333
NLR (3)	0.500	0.636	0.200
Extrahepatic bile duct cancer
CA19-9 (255 IU/mL)	0.273	0.787	0.125
CEA (7 ng/mL)	0.273	0.939	0.333
NLR (3)	0.455	0.727	0.152
Gallbladder cancer
CA19-9 (255 IU/mL)	0.444	0.878	0.444
CEA (7 ng/mL)	0.444	0.878	0.444
NLR (3)	0.889	0.659	0.364

PPV: Positive predictive value; CA19-9: Carbohydrate antigen 19-9; CEA: Carcinoembryonic antigen; NLR: Neutrophil-lymphocyte ratio.