Association of serum pepsinogen with degree of gastric mucosal atrophy in an asymptomatic population

Table 5 Serum pepsinogen levels in the OLGA groups after stratification according to the presence of Helicobacter pylori infection

	OLGA-0		I		II		III		IV
	Helicobacter pylori-(n = 1007)	Helicobacter pylori + (583)	Helicobacter pylori - (n = 99	Helicobacter pylori+ (n = 86)	Helicobacter pylori- (n = 37)	Helicobacter pylori+ (n = 51)	Helicobacter pylori- (n = 16	Helicobacter pylori+ (n = 27)	Helicobacter pylori-(n = 1)	Helicobacter pylori+ (n = 5)
PGI (ng/mL)	82.18 ± 78.64	101.70 ± 89.011	56.71 ± 66.102	73.05 ± 78.201,2	55.40 ± 54.182	92.12 ± 73.511	60.00 ± 47.55	60.8 ± 54.302	34.3	63.50 ± 43.882
PGII (ng/mL)	7.35 ± 6.61	10.80 ± 11.361	6.60 ± 6.31	10.05 ± 10.231	7.10 ± 4.88	13.00 ± 10.491	7.00 ± 6.13	13.5 ± 10.641	3.8	16.40 ± 8.70
PGR	10.68 ± 8.76	8.82 ± 9.891	8.77 ± 5.072	7.24 ± 6.281,2	7.94 ± 3.542	7.18 ± 5.512	8.32 ± 3.25	4.50 ± 3.451,2	9.026316	3.90 ± 2.652

¹P < 0.05, within the same pathological subgroup, compared with the Helicobacter pylori- group.

²P < 0.05, within the same Helicobacter pylori subgroup, compared with the OLGA-0 group.

OLGA: Operative Link for Gastritis Assessment; PG: Pepsinogen; PGR: Pepsinogen I/pepsinogen II ratio.