Retrospective Cohort Study
Copyright ©The Author(s) 2021.
World J Clin Cases. Nov 6, 2021; 9(31): 9406-9416
Published online Nov 6, 2021. doi: 10.12998/wjcc.v9.i31.9406
Table 1 Comparison of demographic and clinical characteristics for deep venous thrombosis after artificial liver support system in Stage I
Parameters
DVT (n = 12)
No-DVT (n = 220)
Statistics
P value
Gender, n (%)
Man7 (58.3)165 (75)1.6490.306
Woman5 (41.7)55 (25)
Age (yrs), n (%)
< 402 (18.2)51 (28.7)7.170.027
< 60, ≥ 404 (36.4)101 (56.7)
≥ 605 (45.5)26 (14.6)
Mean arterial pressure (mmHg), mean ± SD83.45 ± 14.4784.11 ± 13.260.7680.707
Fasting plasma glucose (mmol/L), mean ± SD5.43 ± 1.515.41 ± 1.650.3320.542
Smoke, n (%)
No7 (58.3)142 (64.5)0.1970.759
Yes5 (41.7)78 (35.5)
Catheterization mode, n (%)
Jugular vein 0 (0)72 (30)5.090.022
Femoral vein 12 (100)168 (70)
Times of successful catheterization, n (%)
One3 (25)151 (71.9)16.6690
Two4 (33.3)41 (19.5)
Three and more5 (21.7)18 (8.6)
Heparin therapy, n (%)
No3 (25)56 (25.5)0.010.971
Yes9 (75)164 (74.5)
Procoagulant therapy, n (%)
No8 (67.7)164 (74.5)0.3680.513
Yes4 (33.3)56 (125.5)
Etiology, n (%)
Virus hepatitis9 (75)133 (60.5)1.0280.795
Drug injury1 (8.3)29 (13.2)
Autoimmune liver disease1 (8.3)24 (11.8)
Others1 (8.3)32 (14.5)
ALSS times, n (%)
< 33 (25)61 (27.7)7.3440.025
≥ 3, < 55 (21.7)139 (63.2)
≥ 54 (33.3)20 (9.1)
Activity status, n (%)
Free activities0 (0)23 (10.5)10.7730.013
Less than 4 h/d2 (16.7)89 (40.5)
Less than 1 h/d4 (33.3)74 (33.6)
Strict bed rest6 (50.0)32 (15.5)
Ascites status, n (%)
No3 (25)67 (28.1)0.9230.82
Mild4 (33.3)79 (37.6)
Moderate3 (25)56 (25.7)
Severe2 (16.7)19 (8.6)
Bleeding, n (%)
No8 (67.7)153 (69.5)0.4360.833
Yes4 (33.3)67 (30.5)
Hepatic encephalopathy, n (%)
No6 (54.5)148 (67.3)1.9330.385
I-II4 (33.3)55 (25.0)
III-IV2 (17.5)17 (7.7)
Infection, n (%)
No4 (33.3)144 (65.5)5.0830.031
Yes8 (67.7)76 (34.5)
Complicated by other serious diseases, n (%)
No8 (67.7)174 (79.1)1.0390.294
Yes4 (33.3)46 (20.9)
Body mass index (kg/m2), n (%)
< 232 (20.0)77 (35)2.2620.332
≥ 23, < 254(40.0)97 (44.1)
≥ 254 (40.0)46 (20.9)
Platelet count (109/L), n (%)
< 1003 (25)99 (45)2.2580.277
≥ 100, < 3008 (66.7)95 (43.2)
≥ 3001 (8.3)16 (11.8)
Total bilirubin (μmol/L), mean ± SD234.45 ± 155.12231.65 ± 132.861.4760.583
Alanine aminotransferase (U/L), mean ± SD256.82 ± 243.455294.65 ± 341.361.20·0.578
D-dimer (ng/mL), n (%)
< 2001 (8.3)88 (40)12.2320.002
≥ 200, < 5003 (25.9)82 (37.3)
≥ 5008 (66.7)50 (22.7)
Fibrinogen (g/L), mean ± SD1.25 ± 0.431.33 ± 1.122.5540.212
International normalized ratio, n (%)
< 1.50 (0)0 (0)0.2150.767
≥ 1.5, < 26 (54.5)125 (56.8)
≥ 26 (45.5)85 (43.2)