Diagnosis and treatment of acute graft-versus-host disease after liver transplantation: Report of six cases

Table 2 Main clinical characteristics of six liver transplantation patients with acute graft-versus-host disease

Patients	Initial symptom	Involved systems	From LT to GVHD (d)	Diagnostic tools	From LT to biopsy(d)	From GVHD to diagnosis(d)	Skin biopsy	GVHD related death	Ferritin level (ng/mL)	Survival day	Mortality cause
Case 1	Fever	Skin, GI, BM	15	Skin biopsy, bone marrow smear	24	9	Grade II	Yes	-	31	Cerebral hemorrhage
Case 2	Pancytopenia	Skin, BM	28	Skin biopsy, bone marrow smear	32	4	Grade II	No	-	180	Tuberculosis
Case 3	Fever	Skin, GI, BM	24	Skin biopsy, bone marrow smear	34	10	Grade II	Yes	-	51	Sepsis
Case 4	Fever	Skin, BM, CNS	17	Skin biopsy	19	2	Grade III	Yes	31527	21	Sepsis
Case 5	Fever	Skin, GI, BM	31	Skin biopsy, bone marrow smear	38	7	Grade II	No	-	Alive	-
Case 6	Fever	Skin, GI, BM	18	Skin biopsy	31	13	Grade III	Yes	-	45	Sepsis

LT: Liver transplantation; GVHD: Graft-versus-host disease; GI: Gastrointestinal; BM: Bone marrow.